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Perricone MD Rejuvenating Moisturizer for acne-prone skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Perricone MD Rejuvenating Moisturizer

Average

  • AverageCombination Skin Fit
  • AverageEffectiveness
  • Low RiskSafety

Works for acne-prone skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for your combination skin, as glycerin and tetrahexyldecyl ascorbate provide hydration and antioxidant benefits, though they do not directly target your acne, blemishes, and breakouts.
  • The formula provides excellent moisturization with glycerin and dimethicone, smoothing skin texture and supporting overall skin health.
  • The product is generally safe for your combination skin, with a low risk of irritation from lactic acid and parfum.

How to apply

  • Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
  • Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
  • Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
  • Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
  • Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.

People Say

★4.6Overall rating based on 1.0k+ reviews

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

Highlights

  • Deeply hydrating Often Mentioned
    • “Keeps my skin moist without the acne.”
    • “Very rich and nourishing.”
    • “Replenishes fragile skin.”
  • Improves texture Often Mentioned
    • “Skin looks smoother, with no discoloration.”
    • “Visibly plumper, firmer, and smoother.”
    • “Skin feels better, smoother and brighter.”
  • Non-greasy formula Sometimes Noted
    • “It's non greasy, absorbs right in.”
    • “Absorbs quickly without any residual grease.”
    • “Not greasy or sticky.”
  • Reduces lines Sometimes Noted
    • “Plumps my skin to reduce the look of fine lines.”
    • “Targets deep wrinkles and creases.”
    • “Saw a reduction in the appearance of fine lines.”
  • Product pilling Sometimes Noted
    • “When I try to apply my liquid makeup over it it rolls up.”
    • “It all pealed away. It looked like a snow storm.”
    • “I do not really experience pilling unless I use too much.”
  • Fragrance sensitivity Rarely Noted
    • “A few reviewers found the fragrance too strong.”
    • “Unfortunately had an allergic reaction.”
    • “Experienced minor irritation.”
  • White cast Rarely Noted
    • “Leaves this white flaky texture on my face.”
    • “Had to really blend so it didn't appear to leave a white cast.”
    • “Doesn't leave a whitecast (after 7 days).”

Sources: lovi.care, perriconemd.com, lovelyskin.com, walmart.com, ipsy.com, nordstrom.com, and more

Questions and answers

How well does Perricone MD Rejuvenating Moisturizer work for acne-prone skin?

This moisturizer works moderately well for acne-prone skin, providing hydration and smoothing texture, though it does not directly target breakouts. An ideal product for this skin needs ingredients that address blemishes and calm the skin while offering balanced moisture without irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for acne-prone skin?

Glycerin and tetrahexyldecyl ascorbate help make this cream a moderate fit for your acne-prone skin by providing hydration and antioxidant benefits. However, because these ingredients do not directly target blemishes, an acne-prone skin type needs a product with ingredients that actively clear breakouts, calm irritation, and support overall skin balance.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Acyl-Glutathione do for acne-prone skin?

Acyl-Glutathione helps support antioxidant defense and calm skin, but acne-prone skin typically needs ingredients that clear pores and reduce breakouts.

The Journal of Clinical and Aesthetic Dermatology, 2025

What does Vitamin C do for acne-prone skin?

Vitamin C helps brighten dark spots left behind by breakouts and calms redness in acne-prone skin. Daily use may also help improve overall skin clarity and support an even skin tone.

Journal of Cosmetic Dermatology, 2024Journal of Cosmetic Dermatology, 2019

Where does it go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in the morning routine after a hydrating toner and before sunscreen, and in the evening routine as the final step after your treatment. This type of product needs ingredients that soothe breakouts and lightweight hydrators to keep acne-prone skin clear and balanced.

Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first and following with the moisturizer. This routine helps smooth skin and keeps your skin barrier comfortable while you use active treatments.

Cutis, 2006

How often should I use it?

You can use this moisturizing treatment twice daily as part of your morning and evening routine. Regular daily application helps improve overall skin hydration and smooth skin texture. Acne-prone skin needs a product that includes targeted blemish-fighting ingredients and oil-control components to properly manage breakouts.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream works for acne-prone skin, though other products fit it better because its ingredients provide hydration and smoothing rather than directly targeting blemishes and breakouts. To properly care for acne-prone skin, a product of this type needs acne-fighting ingredients like salicylic acid or benzoyl peroxide to help clear pores and prevent breakouts.

Can I use it around the eyes or on my body?

This moisturizer is generally safe to use on the delicate skin around your eyes and on your body, though it is formulated primarily for facial use. Its nourishing oils and vitamins help smooth and hydrate these areas without causing irritation, much like it does on the face.

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

Why other moisturizers fit acne-prone skin better

Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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