Medicube Zero Foam Cleanser for acne-prone skin

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Questions and answers

What the research says

• All three treatments—benzoyl peroxide, benzoyl peroxide plus erythromycin, and the combination of niacinamide, gallic acid, and lauric acid—were effective in reducing acne vulgaris severity in ninety patients over eight weeks.

  Dermatologic Therapy, 2020

• Camellia japonica flower extract protects against urban air pollutant-induced skin damage by scavenging radicals, inhibiting ROS generation, reducing MMP-1 and lipid peroxidation, and increasing collagen synthesis in in vitro and ex vivo models.

  BMC Complementary and Alternative Medicine, 2019

• Camellia japonica oil activated the human COL1A2 promoter, induced type I procollagen synthesis, inhibited matrix metalloproteinase-1 activity, and reduced trans-epidermal water loss without inducing adverse reactions in human skin.

  Journal of Ethnopharmacology, 2007

• Portulaca oleracea extract ameliorated skin barrier damage and inflammation induced by combined exposure to glycolic acid and UVB in HaCaT cells.

  Cutaneous and Ocular Toxicology, 2022

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Topical purslane at 5% and 10% concentrations achieved alleviation of symptoms and lesion remission comparable to topical 0.1% triamcinolone acetonide in 34 subjects with oral lichen planus over 90 days.

  BMC Oral Health, 2023

• Facial masks containing low-temperature extracted Portulaca oleracea protect sensitive skin from photothermal stimulation and improve skin barrier function during photorejuvenation.

  Cutaneous and Ocular Toxicology, 2025

• Topical application of a crude extract of Portulaca oleracea accelerates wound healing by decreasing wound surface area and increasing tensile strength in Mus musculus JVI-1, with the greatest contraction achieved at a single dose of 50mg compared to other dosages.

  Journal of Ethnopharmacology, 2003

• Camellia oleifera Abel shell 1,3-butanediol extract decreased facial melanin levels by 59% from baseline at 6 weeks compared to a placebo group showing no effect in 30 female subjects.

  Journal of Cosmetic Dermatology, 2019

• Camellia japonica placenta extract treatment upregulated hair growth marker genes in human follicle dermal papilla cells in vitro and improved scalp moisture, sebum, keratin, and erythema in 42 adult female participants in vivo.

  FEBS Open Bio, 2021

• Camellia oleifera oil demonstrated excellent moisture retention, anti-inflammatory effects, and free radical scavenging, and its inclusion in an emulsion significantly improved antioxidant and moisturizing properties compared to an emulsion without CO oil.

  Molecules, 2024

• Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness.

  Journal of Cosmetic Science, 2007

Ingredients

Water, Glycerin, Myristic Acid, Sorbitol, Palmitic Acid, Potassium Hydroxide, Stearic Acid, Lauric Acid, Cetearyl Olivate, Potassium Cocoyl Glycinate, Sodium Cocoyl Isethionate, Sorbitan Olivate, Potassium Cocoate, Coconut Acid, Butylene Glycol, Sodium Isethionate, Sodium Polyacrylate, Portulaca Oleracea Extract, Gaultheria Procumbens Leaf Extract, Disodium Edta, Camellia Japonica Flower Extract, Propanediol, Diisopropyl Adipate, Lecithin, 1,2-Hexanediol, Saponaria Officinalis Leaf Extract, Acrylic Acid Acrylamidomethyl Propane Sulfonic Acid Copolymer, Dimethylmethoxy Chromanol, Glyceryl Caprylate, Citric Acid, Potassium Sorbate, Sodium Benzoate, Xanthan Gum, Chaenomeles Sinensis Fruit Extract, Citrus Aurantium Dulcis Flower Extract, Melissa Officinalis Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.