Benzoyl peroxide and acetyl hexapeptide-3
Keep them apart
Use them at different times of day, applying the peptide cream in the morning and benzoyl peroxide at night, because they clash and cancel each other out. Benzoyl peroxide breaks down the delicate peptide molecules, making the anti-aging cream useless. You can switch to a gentler spot treatment or wait a few hours between applying them.
All about benzoyl peroxide
All about acetyl hexapeptide-3Benzoyl peroxide products
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Proactiv
Renewing Cleanser
S$34.99
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Clean & Clear
Persa-Gel 10
S$25.46
- Differin Daily Deep Cleanser
- Neutrogena Clear Pore Cleanser/Mask
- Proactiv Repairing Treatment
- Paula's Choice Clear Daily Skin Clearing Treatment
- Galderma Epiduo Gel
- Galderma Benzac AC 5
- CeraVe Acne Foaming Cream Cleanser
- Galderma Benzac AC Mild Strength 2.5% Acne Gel
- PanOxyl Acne Foaming Wash
- PanOxyl Acne Creamy Wash
Acetyl hexapeptide-3 products
- The Ordinary Multi-Peptide + Copper Peptides 1% Serum
- The Ordinary Multi-Peptide + HA Serum
- Medik8 Liquid Peptides
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La Mer
The Treatment Lotion
S$238.16
- Rhode Peptide Glazing Fluid
- The Ordinary Argireline Solution 10%
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Good Molecules
Super Peptide Serum
S$38.42
- Clinique Smart Clinical Repair Wrinkle Correcting Serum
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La Mer
The Renewal Oil
S$466.85
- Est茅e Lauder Micro Essence Treatment Lotion
- The INKEY List Collagen Peptide Serum
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La Mer
The Eye Concentrate
S$337.38
Questions and answers
Can you use benzoyl peroxide and acetyl hexapeptide-3 together?
No, you should keep benzoyl peroxide and acetyl hexapeptide-3 apart in your routine because benzoyl peroxide can oxidize and break down peptides. Acetyl hexapeptide-3 helps smooth wrinkles when used twice daily.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013
Which goes first, benzoyl peroxide or acetyl hexapeptide-3?
Keep benzoyl peroxide and acetyl hexapeptide-3 apart because combining them can denature the peptides and accelerate oxidation. Acetyl hexapeptide-3 may help reduce wrinkles when applied twice daily.
American Journal of Clinical Dermatology, 2013Journal of Cosmetic and Laser Therapy, 2013
Are benzoyl peroxide and acetyl hexapeptide-3 good for sensitive skin?
Benzoyl peroxide and acetyl hexapeptide-3 should be kept apart in your routine because benzoyl peroxide may cause adverse effects and sensitive skin types need to avoid combining reactive oxidative agents with delicate peptides. Acetyl hexapeptide-3 helps reduce wrinkles when applied twice daily.
The Cochrane Database of Systematic Reviews, 2020American Journal of Clinical Dermatology, 2013
Research on benzoyl peroxide and acetyl hexapeptide-3
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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