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Sesderma vs Sebamed

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

Sesderma and Sebamed are well-regarded European skincare lines offering specialized solutions for various complexions. The Spanish brand relies on botanical extracts and active compounds within advanced serums to suit sensitive, hyperpigmented, and aging skin. Meanwhile, the German brand focuses on barrier health through thoughtful moisturizers and gentle cleansers that suit sensitive, reactive, and problematic skin. Ultimately, the two differ in their core formulations, as the former utilizes meticulously engineered formulas while the latter maintains a skin-neutral pH.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG.

sebamed.aesebamed.comen.wikipedia.orgde.wikipedia.org

This page compares some of the most popular Sesderma and Sebamed products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Sesderma vs Sebamed products

Questions and answers

Sesderma or Sebamed: which is better?

Both brands offer solid options, but Sebamed is better for fragrance-sensitive shoppers because the products on this page list no fragrance. Sesderma's Azelac RU Serum holds a High fit for acne-prone skin and skin with dark spots, though it contains fragrance.

Pharmaceutics, 2021

What is the difference between Sesderma and Sebamed?

Sebamed offers fragrance-free formulas with products on this page reaching a High Lovi fit for oily and acne-prone skin, whereas Sesderma includes fragrance in its Azelac RU Serum which achieves a High fit for acne-prone, dark spots, and combination skin.

Which is more affordable, Sesderma or Sebamed?

I am sorry, but the provided page facts and studies do not contain information about the pricing or affordability of Sesderma and Sebamed products.

Which causes fewer breakouts, Sesderma or Sebamed?

Sebamed's products on this page have a High Lovi fit for oily acne-prone skin, whereas Sesderma's Azelac RU Serum has an Average fit for that skin type. Sebamed also has no fragrance across its products on this page, which helps prevent irritation.

Which brand is older and where was each founded?

Sebamed is older, having been founded in Germany in 1967, whereas Sesderma was founded in Spain in 1989.

Do Sesderma and Sebamed products contain fragrance?

Sebamed products on this page list no fragrance in their ingredients, whereas the Sesderma product contains fragrance. Azelac RU Serum by Sesderma includes fragrance.

Which skin types are best suited for the Azelac RU Serum by Sesderma?

For acne-prone skin, skin with dark spots, and combination skin, the Azelac RU Serum by Sesderma achieves a High fit level on Lovi. For oily skin, oily acne-prone skin, sensitive skin, and mature skin, it earns an Average fit level.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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