Mediheal Baobab Soothing Moisture Toner for mature skin

How to apply

Questions and answers

What the research says

• Topical application of an emulsion containing a complete mixture of ceramides III, IIIB, VI, phytosphingosine, cholesterol, and linoleic acid significantly accelerated barrier recovery after SLS damage and improved skin hydration after acetone treatment in human volunteers compared to an emulsion containing only two types of ceramides.

  Journal of the European Academy of Dermatology and Venereology, 2002

• Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.

  American Journal of Clinical Dermatology, 2013

• Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.

  Annals of Dermatology, 2019

• Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.

  Journal of Cosmetic and Laser Therapy, 2013

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• An aqueous extract of baobab seedcake enriched in small RNAs demonstrated more efficient anti-aging and senescence-related marker activity in skin fibroblasts and ex vivo skin compared to a small RNAs-free extract.

  Journal of Cosmetic Science, 2019

• Baobab fruit 30% and 70% ethanol extracts reduced TNF-α/IFN-γ-stimulated secretion of IL-6, IL-8, and MCP-1 in HaCaT keratinocytes in a dose-dependent manner, with the 70% extract showing greater inhibition.

  Pharmaceuticals, 2026

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.

  Journal of Cosmetic Dermatology, 2022

• Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.

  International Journal of Molecular Sciences, 2022

• Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.

  Marine Drugs, 2023

• Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

• A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.

  Aesthetic Plastic Surgery, 2018

Ingredients

Water, Butylene Glycol, Pentylene Glycol, Propanediol, Glycerin, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Xylitylglucoside, Xylitol, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Polymnia Sonchifolia Root Juice, Chitosan, Hydrolyzed Collagen, 1,2-Hexanediol, Ceramide Np, Ceramide Ns, Cholesterol, Ceramide Ap, Ceramide, Betaine, Ceramide Eop, Allantoin, Panthenol, Caprylyl Glycol, Ethylhexylglycerin, Triethylhexanoin, Hydrogenated Lecithin, Sodium Phytate, Phytic Acid, Tromethamine, Diphenyl Dimethicone, Anhydroxylitol, Tocopherol, Dipropylene Glycol, Gluconolactone, Phytosphingosine, Palmitoyl Tripeptide-5, Alpha-Glucan Oligosaccharide, Maltodextrin, Lactobacillus, Phytosterols, Choleth-24, Copper Tripeptide-1, Acetyl Hexapeptide-8, Stearic Acid, Carbomer, Xanthan Gum, Cetearyl Alcohol, Saccharum Officinarum Extract, Chondrus Crispus Extract, Malachite Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.