Epionce Renewal Facial Lotion for oily acne-prone skin

How to apply

Questions and answers

What the research says

• A supramolecular system of malic acid-derived ionic liquid and acetyl hexapeptide-8 enhanced transdermal permeation by 3.10 times, increased collagen production, inhibited acetylcholine release, and reduced wrinkle number, length, and area compared to peptide monotherapy in human subjects.

  Journal of Materials Chemistry. B, 2025

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Safflower oil body-human epidermal growth factor microgel emulsions mixed with xanthan gum enhance transdermal absorption, regulate inflammation, accelerate angiogenesis, and promote re-epithelialization and remodeling in full-layer skin wounds in rats.

  International Journal of Biological Macromolecules, 2022

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• Topical cream containing saffron extract and avocado oil improved wrinkle grading, reduced nasolabial fold area and volume, and increased skin elasticity in twenty healthy volunteers over 12 weeks without allergic reactions.

  Journal of Cosmetic Dermatology, 2020

• Topical treatment with SSFAO 50% or avocado oil increased wound contraction, reepithelialization, collagen density, and tensile strength while showing anti-inflammatory activity compared to petroleum jelly in rats.

  Evidence-based Complementary and Alternative Medicine, 2013

Why other moisturizers fit oily acne-prone skin better

• A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

  Journal of Cosmetic Dermatology, 2024

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

Ingredients

Water, Butylene Glycol, Petrolatum, Cyclopentasiloxane, Carthamus Tinctorius Seed Oil, Glycerin, Ppg-2 Myristyl Ether Propionate, Polyacrylamide, C10-30 Cholesterol Lanosterol Esters, Limnanthes Alba Seed Oil, Laureth-7, C13-14 Isoparaffin, Cyclohexasiloxane, Beeswax, C12-15 Alkyl Benzoate, Caprylyl Glycol, Cetyl Alcohol, Citrus Aurantium Dulcis Peel Oil, Lemon Peel Oil, Cyclotetrasiloxane, Cymbopogon Flexuosus Oil Lemongrass Oil, Dimethiconol, Ethylhexylglycerin, Glyceryl Stearate, Hexylene Glycol, Lavandula Hybrida Oil, Linum Usitatissimum Seed Oil, Litsea Cubeba Oil, Malic Acid, Olea Europaea Oil Olive Oil, Peg-100 Stearate, Persea Gratissima Oil Avocado Oil, Phenoxyethanol, Phoenix Dactylifera Fruit Extract, Phytosphingosine, Phytosterols, Pyrus Malus Fruit Extract, Quercetin, Rosa Canina Seed Oil, Sodium Hyaluronate, Sodium Hydroxide

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.