Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Tocopherol · Journal of Cosmetic Dermatology, 2020Psychophysical study of the effects of topical application of menthol in healthy volunteers
Menthol · Pain, 2006Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells
Sanguisorba officinalis root extract · Phytomedicine, 2015Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo
Sodium lauryl sulfate · The Journal of Investigative Dermatology, 2008Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling
Panax ginseng root extract · Journal of Ethnopharmacology, 2007Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Squalane · Scientific Reports, 2020Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
Camellia sinensis leaf extract · Experimental Dermatology, 2009A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia
Menthol · European Journal of Pain, 2014Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies
Lauric acid · Drug Development and Industrial Pharmacy, 2019Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris
Azelaic acid · Pharmaceutics, 2021The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract
Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
Caffeine · Frontiers in Physiology, 2019High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel leaf extract · Phytochemistry, 2001Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy
Sodium lauryl sulfate · Pharmaceutics, 2021Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris
Azelaic acid · Dermatology and Therapy, 2024A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate
Sodium lauryl sulfate · Inflammation Research, 2010Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)
Sodium laureth sulfate · Food and Chemical Toxicology, 2001Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract
Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study
Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023In vivo and in vitro evaluation of octyl methoxycinnamate liposomes
Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris
Lauric acid · Dermatologic Therapy, 2020Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast
Squalane · Molecules, 2025Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration
Betaine · Molecules, 2024Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry
Myristic acid · Journal of Food Protection, 2005Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders
2-o-ethyl ascorbic acid · Polymers, 2023Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation
Lauric acid · International Journal of Pharmaceutics, 2023Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application
Cyclodextrin · International Journal of Cosmetic Science, 2021Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid
Betaine · Pharmaceutics, 2024Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate · Arzneimittel-Forschung, 1998Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial
Sodium lauryl sulfate · The British Journal of Dermatology, 2019A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants
Dimethicone · Ostomy/wound Management, 2005The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively
Betaine · Skin Research and Technology, 2003Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling
Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Diglycerin · Journal of Oleo Science, 2016Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation
Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study
Theanine · Journal of Clinical Medicine, 2022Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes
2-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025Functional properties and skin care effects of sodium trehalose sulfate
Trehalose · Skin Research and Technology, 2024Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate · Scientific Reports, 2025Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin
Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum
Caprylic capric triglyceride · Life, 2023Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes
Artemisia princeps leaf extract · Molecular Medicine Reports, 2017Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability
2-o-ethyl ascorbic acid · Journal of Liposome Research, 2025Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients
2-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes
Potassium methoxysalicylate · Journal of Cosmetic Dermatology, 2025New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging
Angelica keiskei leaf extract · Pharmaceutics, 2024Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin
Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025Facial disbiosis and UV filters
Ethylhexyl methoxycinnamate, Octocrylene · Archives of Dermatological Research, 2024Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking
Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial
Uji green tea extract · Journal of Cosmetic Dermatology, 2023Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study
Sodium laureth sulfate · International Journal of Pharmaceutics, 2026Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Homosalate · Journal of Drugs in Dermatology, 2025
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