Theramid Copper Peptide for sensitive skin
Copper Tripeptide-1
Acetyl Tetrapeptide-2
Sodium Hyaluronate
Bifida Lysate Ferment
Acetyl Glutamine
High
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
A great choice for sensitive skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your normal skin, this product utilizes copper tripeptide-1 and bifida lysate ferment to stimulate collagen and repair your skin barrier, while also offering excellent skin repair and anti-aging benefits through copper tripeptide-1 and acetyl hexapeptide-1 to improve elasticity and reduce fine lines.
- Glycerin and sodium hyaluronate provide essential hydration to support your redness and irritation.
- The formulation is safe for your sensitive skin, containing no harsh or prohibited ingredients that could cause irritation.
How to apply
- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
People Say
★4.4Overall rating based on 100+ reviewsA lightweight, fast-absorbing texture is frequently praised, and a moderate number of users report a boost in skin radiance. Some users find the high silicone content problematic for layering and note that copper peptides require careful routine planning to avoid conflicts with other active ingredients.
Highlights
Improves firmness Often Mentioned
- “my skin feels incredibly fed and plump”
- “improving skin elasticity and firmness”
- “it felt bouncier and more lifted”
- “helps to improve signs of aging... firm, smooth, radiant, and younger-looking skin”
Lightweight, fast-absorbing Often Mentioned
- “the texture is a sophisticated, lightweight gel that absorbs almost instantly without leaving a sticky residue”
- “absorbs quickly, and doesn't leave any stickiness, which is a huge plus for those of us who prefer to layer products”
- “it feels better on my skin... soaks in much better”
- “light, gel-like consistency absorbs quickly without leaving a tacky residue”
Boosts radiance Sometimes Noted
- “instantly gives the skin a radiant glow and freshness”
- “my skin has gotten a lot brighter and a lot better”
- “helps my complexion look lively”
- “promote a more youthful glow”
Gentle, non-irritating Sometimes Noted
- “incredibly gentle... I experienced zero redness or irritation”
- “I experienced no redness or dryness, which is often a concern when introducing strong active ingredients”
- “perfect for beginners, sensitive skin”
Hard to combine Sometimes Noted
- “copper peptides are high maintenance... you really don't want to use it in with anything that has a low pH”
- “I wouldn't recommend using it together with Niactilen”
- “Do not use with other acids and retinol products”
High silicone content Rarely Noted
- “I don't like the fact that is has so much silicone in it”
- “makes it very difficult to rub on the skin, because it 'sticks' to first place you put it and doesn't blend well”
- “This broke me out on my face”
No visible results Rarely Noted
- “Nearly 2 months in, no result”
- “No Effect”
- “I have it, I can't say how effective it is”
Sources: lovi.care, peptides133.com, peptides136.com, peptides138.com, youtube.com, lyko.com, and more
Questions and answers
What makes Theramid Copper Peptide Serum a great fit for sensitive skin?
Theramid Copper Peptide Serum is a great fit because it uses copper tripeptide-1 and bifida lysate ferment to repair your skin barrier, while glycerin and sodium hyaluronate provide essential hydration to calm redness and irritation. The formulation is also very safe for your skin, containing no harsh ingredients that could trigger discomfort.
Skin Research and Technology, 2026Clinical, Cosmetic and Investigational Dermatology, 2017
Which ingredients make this serum a good fit for sensitive skin?
Copper tripeptide-1 and bifida lysate ferment make this serum a great fit because they repair your skin barrier and calm irritation, while glycerin and sodium hyaluronate provide essential hydration.
Skin Research and Technology, 2026Clinical, Cosmetic and Investigational Dermatology, 2017
What does Copper Tripeptide-1 do for sensitive skin?
Copper Tripeptide-1 helps calm sensitive skin by reducing inflammation and supports tissue repair for a healthier barrier. It may also improve firmness and reduce signs of aging while being gentle enough for daily use.
Skin Research and Technology, 2026Journal of Biomaterials Science. Polymer Edition, 2008
What does Acetyl Tetrapeptide-2 do for sensitive skin?
Acetyl Tetrapeptide-2 helps firm and protect sensitive skin by supporting natural defenses against daily stress and aging. This ingredient is generally well tolerated, though sensitive skin types may benefit from formulas that also include soothing hydrators to keep the skin calm and smooth.
Where does this serum go in a skincare routine for sensitive skin?
This serum goes in your evening routine, applied after your soothing toner and before your moisturizer. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure, while helping your skin barrier stay calm.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying your retinol first at night, letting it absorb, and then following with this treatment serum to help repair your skin barrier. This formulation is safe and gentle for sensitive skin, though using strong actives together may occasionally cause mild dryness.
How often should I use this serum?
This treatment is applied in the evening as part of your routine. It is safe for sensitive skin and helps keep your skin calm while smoothing fine lines.
Can this serum clog pores, cause breakouts or purging for sensitive skin?
This serum is unlikely to clog pores or cause breakouts for sensitive skin because its formulation contains no harsh or prohibited ingredients that could trigger irritation. Glycerin and sodium hyaluronate provide gentle hydration, while copper tripeptide-1 and bifida lysate ferment help repair the skin barrier safely.
Skin Research and Technology, 2026Clinical, Cosmetic and Investigational Dermatology, 2017
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls.
Skin Research and Technology, 2026A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality.
Archives of Facial Plastic Surgery, 2006A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days.
Cureus, 2024Copper applied transdermally as a tripeptide on human skin ex vivo permeated the tissue and was retained in amounts potentially effective for treating inflammatory diseases.
Inflammation Research, 2010Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls.
International Journal of Peptide Research and Therapeutics, 2018Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023
Ingredients
Water, Propanediol, Cyclopentasiloxane, Dimethicone, Betaine, Copper Tripeptide-1, Bifida Lysate Ferment, Cyclohexasiloxane, Glycerin, Sodium Chloride, Polyglyceryl-4 Isostearate, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-1, Bacillus Folic Acid Extract Ferment Filtrate, Cetyl Peg Ppg-10 1 Dimethicone, Hexyl Laurate, Peg Ppg-18 18 Dimethicone, Lecithin, Acetyl Glutamine, Caprylyl Glycol, Butylene Glycol, Dextran, Disodium Edta, Acetic Acid, Lactic Acid, 1,2-Hexanediol, Sodium Benzoate, Phenoxyethanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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