Perricone MD Rebalancing Elixir for oily skin

Cannabidiol
Mushroom Complex
Cherimoya Fruit Extract
Capryloyl Glycine
Sodium Pca
Average
- AverageOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for oily skin, as triethyl citrate and capryloyl glycine help regulate sebum production to manage oiliness. Annona cherimola fruit extract and sodium bicarbonate provide some mattifying effects, though stronger oil-controlling ingredients would enhance results for your oily shine.
- Cannabidiol and mushroom extracts offer general skincare benefits like hydration and soothing, which are supportive but not primary for addressing your specific concerns of oily shine.
- The product is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
People Say
★4.5Overall rating based on 800+ reviewsMost users find it provides lightweight hydration that absorbs quickly without feeling heavy, leading to improved skin balance and texture. A moderate number of users feel the product is too expensive for the results, and a low number dislike the natural scent or do not see dramatic anti-aging effects.
Highlights
Soothes sensitive skin Mostly Mentioned
- “soothed irritation instantly”
- “no stinging on application”
- “relief was real”
Lightweight hydration Often Mentioned
- “absorbs super quickly”
- “skin feels hydrated not oily”
- “lightweight moisture boost”
- “perfect for oily/combo skin”
Good for layering Sometimes Noted
- “makeup went right over it”
- “great base for serums”
- “didn't pill under moisturizer”
- “compatible with hyaluronic acid”
Improves skin texture Sometimes Noted
- “softening effect overall”
- “skin shines bright”
- “balanced my pH”
- “smooths texture perfectly”
Expensive for results Sometimes Noted
- “doesn't justify the price”
- “very expensive for a toner”
- “expected more for the cost”
- “pricey investment”
Not a miracle worker Rarely Noted
- “didn't do miracles”
- “just okay hydration”
- “didn't see major changes”
- “good but not amazing”
Product availability issues Rarely Noted
- “hard to find stock”
- “range has been discontinued”
- “replaced by new line”
- “out of stock everywhere”
Unpleasant natural scent Rarely Noted
- “organic almost gamey scent”
- “smells like mushrooms”
- “scent lingers slightly”
- “weird natural smell”
Sources: lovi.care, perriconemd.com, macys.com, influenster.com, lookfantastic.com, menstylefashion.com, and more
Questions and answers
How well does Perricone MD Rebalancing Elixir work for oily skin?
Perricone MD Rebalancing Elixir works moderately well for oily skin by helping control sebum production and reducing oily shine. A treatment of this type needs stronger oil-controlling ingredients, along with salicylic acid or willow bark extract and tea tree extract, to better manage oily shine and purify the skin.
The British Journal of Dermatology, 2007Journal of Cosmetic Dermatology, 2023
Which ingredients make this toner a good fit for oily skin?
Triethyl citrate, capryloyl glycine, annona cherimola fruit extract, and sodium bicarbonate help manage oily shine by regulating oil production and mattifying the skin. Cannabidiol and mushroom extracts provide helpful hydration and soothing benefits. An oily skin type needs strong oil-controlling ingredients, purifying extracts like tea tree, and blemish-clearing components such as salicylic acid and willow bark extract to achieve the best results.
The British Journal of Dermatology, 2007The Journal of Reproductive Medicine, 1991
What does Cannabidiol do for oily skin?
Cannabidiol helps balance oily skin by calming irritation and regulating oil production in the skin's glands. It may also help keep pores clear and reduce redness associated with breakouts.
The Journal of Clinical Investigation, 2014Experimental Dermatology, 2016
What does Mushroom Complex do for oily skin?
Mushroom Complex helps balance oily skin by keeping it calm and hydrated without feeling heavy. It is unlikely to clog pores and helps keep the skin looking fresh throughout the day.
Where does it go in a skincare routine for oily skin?
This treatment goes in the evening routine, as treatments with actives are placed in the pm for simplicity and extra safety around sun exposure. It works for oily skin, though this skin type needs stronger oil-controlling ingredients like salicylic acid or niacinamide to better manage shine.
Can I use it with retinol, and in what order?
You can use this treatment alongside retinol by applying it during your evening routine after cleansing and before your moisturizer. It is unlikely to cause irritation, but an oily skin type needs stronger oil-controlling ingredients and mattifying agents like niacinamide or salicylic acid to better manage shine.
How often should I use it?
You can use this treatment in the evening as part of your routine. Oily skin needs stronger oil-controlling and mattifying ingredients to better manage oily shine.
Can it clog pores, cause breakouts or purging for oily skin?
Perricone MD Rebalancing Elixir is unlikely to clog pores or cause breakouts for oily skin, as it is free of harsh ingredients and uses components that help regulate oil production. However, because it offers only moderate oil control, oily skin often needs stronger mattifying and oil-balancing ingredients to fully manage shine and prevent breakouts.
The British Journal of Dermatology, 2007The Journal of Reproductive Medicine, 1991
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A lotion containing triethyl citrate and ethyl linoleate reduced Leeds grading, total, inflammatory, and noninflammatory lesion counts, and sebum production compared with a placebo in patients with mild to moderate acne.
The British Journal of Dermatology, 2007Topical application of an anti-aging gel containing EPA and CBD reduced inflammatory agents, decreased crow's feet and fine line wrinkle volume, reduced the subepidermal low-echogenic band by 8.8%, and increased skin hydration by 31.2% and elasticity by 25.6% in 33 participants over 56 days compared to baseline.
Journal of Cosmetic Dermatology, 2023Topical nano-cannabidiol cream reduced UV-A-induced epidermal hyperplasia, nuclear DNA base lesions, and mitochondrial DNA deletions compared with vehicle in nineteen participants.
Journal of the American Academy of Dermatology, 2024Menstrual pads containing sodium bicarbonate caused no clinical signs or subclinical vulvar skin irritant reactions in 50 healthy women after 24 hours of patch testing.
The Journal of Reproductive Medicine, 1991Daily application of a novel retinol and cannabidiol combination topical improved global skin quality across 13 domains, including visible pores, dehydration, surface roughness, and static and dynamic wrinkles, in 10 patients with facial skin imperfections.
Aesthetic Surgery Journal. Open Forum, 2022Topical application of carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol reduced inflammation and increased collagen production in radiation-combined wound skin injury in mice.
Phytomedicine, 2025Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.
Journal of Cosmetic Dermatology, 2021Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.
Dermatology and Therapy, 2023Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.
The Journal of Dermatology, 2022Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days.
Journal of Cosmetic Dermatology, 2021A novel natural carrier-free assembled gel composed of sodium pyrrolidone carboxylate and baicalin alleviates UVB-induced skin photodamage by scavenging reactive oxygen species, protecting mitochondria, restoring oxidative homeostasis, inhibiting inflammatory responses, and regulating collagen-related proteins.
Biomaterials Advances, 2026
Why other serums fit oily skin better
An O/W cosmetic formula containing 2% Orthosiphon stamineus leaf extract reduced the oily appearance of skin, pore size, and improved complexion evenness and radiance in Caucasian and Asian volunteers compared to a formula with 1% zinc gluconate.
International Journal of Cosmetic Science, 2011
Ingredients
Water, 1,2-Hexanediol, Sodium Pca, Triethyl Citrate, Propanediol, Capryloyl Glycine, Glycerin, Annona Cherimola Fruit Extract, Cannabidiol, Ganoderma Lucidum Stem Extract Mushroom Stem Extract, Grifola Frondosa Fruiting Body Extract, Sodium Bicarbonate, Caprylhydroxamic Acid, Sodium Hydroxide, Citric Acid, Cannabis Sativa Glycereth-8 Esters Seed Oil, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Citrate, Lentinus Edodes Mycelium Extract, Sodium Dehydroacetate, Phenylpropanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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