Perricone MD Rebalancing Elixir for oily acne-prone skin
Cannabidiol
Mushroom Complex
Cherimoya Fruit Extract
Capryloyl Glycine
Sodium Pca
High
- HighOily Skin Fit
- HighEffectiveness
- HighSafety
A great choice for oily acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent treatment for your oily skin, as capryloyl glycine and sodium bicarbonate effectively mattify and control oil production, while triethyl citrate aids in seboregulation.
- Cannabidiol and Annona Cherimola Fruit Extract provide soothing benefits and help regulate sebum, offering moderate improvements for your acne, blemishes, and breakouts.
- The formula is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.5Overall rating based on 800+ reviewsMost users find it provides lightweight hydration that absorbs quickly without feeling heavy, leading to improved skin balance and texture. A moderate number of users feel the product is too expensive for the results, and a low number dislike the natural scent or do not see dramatic anti-aging effects.
Highlights
Soothes sensitive skin Mostly Mentioned
- “soothed irritation instantly”
- “no stinging on application”
- “relief was real”
Lightweight hydration Often Mentioned
- “absorbs super quickly”
- “skin feels hydrated not oily”
- “lightweight moisture boost”
- “perfect for oily/combo skin”
Good for layering Sometimes Noted
- “makeup went right over it”
- “great base for serums”
- “didn't pill under moisturizer”
- “compatible with hyaluronic acid”
Improves skin texture Sometimes Noted
- “softening effect overall”
- “skin shines bright”
- “balanced my pH”
- “smooths texture perfectly”
Expensive for results Sometimes Noted
- “doesn't justify the price”
- “very expensive for a toner”
- “expected more for the cost”
- “pricey investment”
Not a miracle worker Rarely Noted
- “didn't do miracles”
- “just okay hydration”
- “didn't see major changes”
- “good but not amazing”
Product availability issues Rarely Noted
- “hard to find stock”
- “range has been discontinued”
- “replaced by new line”
- “out of stock everywhere”
Unpleasant natural scent Rarely Noted
- “organic almost gamey scent”
- “smells like mushrooms”
- “scent lingers slightly”
- “weird natural smell”
Sources: lovi.care, perriconemd.com, macys.com, influenster.com, lookfantastic.com, menstylefashion.com, and more
Questions and answers
What makes Perricone MD Rebalancing Elixir a great fit for oily acne-prone skin?
Perricone MD Rebalancing Elixir is a great fit because capryloyl glycine and sodium bicarbonate effectively mattify and control oil production, while triethyl citrate helps regulate sebum. Cannabidiol and cherimoya fruit extract provide soothing benefits and help improve blemishes and breakouts safely without irritation.
The British Journal of Dermatology, 2007Dermatologic Surgery, 2013
Which ingredients make this elixir a good fit for oily acne-prone skin?
Capryloyl glycine, sodium bicarbonate, and triethyl citrate make this elixir a great fit by controlling oil and keeping skin shine-free. Cannabidiol and cherimoya fruit extract also help calm the skin and improve blemishes without any harshness.
What does Cannabidiol do for oily acne-prone skin?
Cannabidiol helps balance oily, acne-prone skin by calming redness and reducing excess oil production. It works by regulating the skin's oil-producing glands to keep pores clear and the complexion calm.
What does Mushroom Complex do for oily acne-prone skin?
Mushroom Complex helps hydrate and protect oily acne-prone skin while supporting the skin barrier without clogging pores. Because this product is a weaker fit for your skin, an ideal product of this type needs lightweight hydrators and soothing ingredients to calm breakouts and control excess oil.
Where does it go in a skincare routine for oily acne-prone skin?
This treatment goes in your evening routine, applied after cleansing and before your moisturizer. Putting it in the evening keeps things simple and adds extra safety around sun exposure, though some treatments can also be used in the morning or twice a day.
Can I use this elixir with retinol, and in what order?
Yes, you can use this elixir in your routine with retinol, but apply your retinol first and follow with this treatment to keep your oily skin calm and clear. This product is very safe for your skin type and is unlikely to cause irritation.
How often should I use it?
Use this treatment in the evening as part of your routine. It is safe for daily use on oily skin and helps control excess oil and breakouts without irritation.
Can this elixir clog pores, cause breakouts or purging for oily acne-prone skin?
This elixir is unlikely to clog pores or cause breakouts for oily acne-prone skin, as it is safe with no harsh ingredients. Its cannabidiol and mushroom complex help calm your skin.
Journal of the American Academy of Dermatology, 2024Journal of Cosmetic Dermatology, 2023
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A lotion containing triethyl citrate and ethyl linoleate reduced Leeds grading, total, inflammatory, and noninflammatory lesion counts, and sebum production compared with a placebo in patients with mild to moderate acne.
The British Journal of Dermatology, 2007A combined chemo-exfoliation and home therapy regimen reduced the average GAGS score by 49% in 53 patients with moderate facial acne.
Dermatologic Surgery, 2013Topical nano-cannabidiol cream reduced UV-A-induced epidermal hyperplasia, nuclear DNA base lesions, and mitochondrial DNA deletions compared with vehicle in nineteen participants.
Journal of the American Academy of Dermatology, 2024Topical application of an anti-aging gel containing EPA and CBD reduced inflammatory agents, decreased crow's feet and fine line wrinkle volume, reduced the subepidermal low-echogenic band by 8.8%, and increased skin hydration by 31.2% and elasticity by 25.6% in 33 participants over 56 days compared to baseline.
Journal of Cosmetic Dermatology, 2023Daily application of a novel retinol and cannabidiol combination topical improved global skin quality across 13 domains, including visible pores, dehydration, surface roughness, and static and dynamic wrinkles, in 10 patients with facial skin imperfections.
Aesthetic Surgery Journal. Open Forum, 2022Topical application of carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol reduced inflammation and increased collagen production in radiation-combined wound skin injury in mice.
Phytomedicine, 2025Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.
Journal of Cosmetic Dermatology, 2021Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.
Dermatology and Therapy, 2023Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.
The Journal of Dermatology, 2022Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days.
Journal of Cosmetic Dermatology, 2021A novel natural carrier-free assembled gel composed of sodium pyrrolidone carboxylate and baicalin alleviates UVB-induced skin photodamage by scavenging reactive oxygen species, protecting mitochondria, restoring oxidative homeostasis, inhibiting inflammatory responses, and regulating collagen-related proteins.
Biomaterials Advances, 2026
Ingredients
Water, 1,2-Hexanediol, Sodium Pca, Triethyl Citrate, Propanediol, Capryloyl Glycine, Glycerin, Annona Cherimola Fruit Extract, Cannabidiol, Ganoderma Lucidum Stem Extract Mushroom Stem Extract, Grifola Frondosa Fruiting Body Extract, Sodium Bicarbonate, Caprylhydroxamic Acid, Sodium Hydroxide, Citric Acid, Cannabis Sativa Glycereth-8 Esters Seed Oil, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Citrate, Lentinus Edodes Mycelium Extract, Sodium Dehydroacetate, Phenylpropanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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