Medicube PDRN Pink Collagen Gel Mask for dry skin
Sodium Dna
Niacinamide
Hydrolyzed CollagenAverage
- SuperiorDry Skin Fit
- HighEffectiveness
- HighSafety
Works for dry skin; other nourishing masks fit it better.
- International Journal of Molecular Sciences, 2025
- International Journal of Biological Macromolecules, 2025
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your dry or flaky skin as sodium DNA and hydrolyzed collagen provide hydration and improve skin elasticity. Niacinamide further supports skin barrier function and offers mild anti-inflammatory benefits.
- The formulation is well-suited for dry skin, providing deep nourishment and humectant actions.
- The product is safe for your dry skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your sheet mask PM or AM whenever your skin feels dry. Start 3 times a week and increase if your skin likes it.
- Place the sheet mask on your face after cleansing and toner, and before moisturizer.
- Unfold the sheet mask and smooth it gently over your face without rubbing. Relax for ten minutes and let the essence soak in.
- Put the sheet mask on clean and slightly damp skin for the best hydration boost. Pat the remaining liquid softly into your skin.
- Avoid getting the essence too close to your eyes. Do a quick patch test before your very first use.
People Say
★4.4Overall rating based on 4.6k+ reviewsBased on a very large amount of data, users with dry, dull, or aging skin frequently praise this mask for delivering a "glass skin" glow and deep hydration that plumps fine lines and revitalizes the complexion. The cooling effect and post-facial radiance are highly rated by many users. Some users find the application messy, the price point high, and the required wear time inconvenient.
Highlights
Hydration and glow Mostly Mentioned
- “glass skin”
- “juicy”
- “plump”
- “radiant”
Soothing and cooling Often Mentioned
- “refreshing sensation”
- “melts away stress”
- “reduces redness”
- “wonderfully cooling”
Expensive product Often Mentioned
- “price is steep”
- “wallet is crying”
- “only buy during a sale”
Messy application Often Mentioned
- “messy”
- “slippery”
- “gooey”
- “sliding down”
Good adherence Sometimes Noted
- “stays put”
- “doesn't slide around”
- “doesn't stick to hair”
Plumping effect Sometimes Noted
- “fine lines vanished”
- “snatched and tight”
- “bouncy”
- “firm”
Poor fit Sometimes Noted
- “lifted around the nose/eyes”
- “gaps”
- “trim with scissors”
Skin irritation Rarely Noted
- “stinging”
- “burning sensation”
- “redness”
Sources: lovi.care, amazon.com, oliveyoung.com, stylekorean.com, iherb.com, elle.com, and more
Questions and answers
How well does the medicube PDRN Pink Collagen Gel Mask work for dry skin?
This mask works moderately well for dry skin, as sodium DNA and hydrolyzed collagen help provide hydration while niacinamide supports the skin barrier. A dry skin type needs a product rich in hyaluronic acid, glycerin, and other soothing, moisturizing ingredients that deliver deep hydration and relief without any risk of irritation.
Which ingredients make this mask a good fit for dry skin?
Sodium DNA, niacinamide, and hydrolyzed collagen make this mask a good fit because they help hydrate, improve elasticity, and support your skin barrier. A nourishing mask for dry skin needs effective hydrating ingredients like hyaluronic acid and glycerin, alongside soothing components that provide deep moisture and relief without irritation.
What does Sodium DNA do for dry skin?
Sodium DNA helps improve hydration and supports barrier recovery in dry skin. It helps repair the skin barrier and keeps the skin feeling smooth and comfortable.
Journal of Cosmetic Dermatology, 2026Skin Research and Technology, 2024
What does Niacinamide do for dry skin?
Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Journal of Cosmetic Dermatology, 2004Journal of Cosmetic Dermatology, 2026
Where does it go in a skincare routine for dry skin?
This nourishing mask goes in your weekly routine after your cleanser and before your treatment and moisturizer. A product of this type for dry skin needs ingredients that provide deep hydration, improve elasticity, and support the skin barrier, such as sodium DNA, hydrolyzed collagen, and niacinamide.
Can I use this mask with retinol, and in what order?
You can use this mask with retinol, applying the mask on your weekly self-care night after cleansing and before your retinol treatment and moisturizer. This product helps provide deep nourishment and keeps skin safe from irritation, though dry skin often benefits even more from a dedicated barrier-repair cream with ceramides and heavy oils.
How often should I use it?
Use this nourishing mask once a week as part of your weekly routine. Regular application helps provide deep hydration and nourishment for dry skin.
Can this mask clog pores, cause breakouts or purging for dry skin?
This nourishing mask is unlikely to clog pores or cause breakouts on dry skin, as its formula contains no harsh or heavy ingredients that typically trigger irritation. It helps keep your skin calm and comfortable while delivering deep hydration and barrier support.
What the research says
Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects.
International Journal of Molecular Sciences, 2025Polydeoxyribonucleotide-spermidine nanoparticles improved skin anti-aging efficacy, enhanced cell migration by 25.63 %, increased in vitro percutaneous permeability by 202.3 %, and boosted in vivo permeability by 143.4 %.
International Journal of Biological Macromolecules, 2025Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes.
Molecular Medicine Reports, 2023A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model.
Molecules, 2022Polydeoxyribonucleotide treatment induces mitochondrial biogenesis while reducing melanin biosynthesis, tyrosinase activity, MITF expression, elastase activity, and MMP-1 gene expression in cultured skin cells.
Applied Biochemistry and Biotechnology, 2020Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023
Ingredients
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.