BIOEFFECT EGF Power Serum for dry sensitive skin
Rh-Oligopeptide-1
Sodium Hyaluronate
Acetyl Glucosamine
Hordeum Vulgare Seed Extract
Glycerin
High
- HighDry Skin Fit
- HighEffectiveness
- HighSafety
A great choice for dry sensitive skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your dry and sensitive skin, this serum offers excellent skin regeneration with Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1 and Kgf Barley Sh-Polypeptide-3 to improve elasticity and reduce fine lines.
- Moderate hydration is provided by Glycerin and Sodium Hyaluronate, while Hordeum Vulgare Seed Extract aids in barrier repair, addressing your dry or flaky skin concerns.
- The safety profile is excellent, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
People Say
★4.7Overall rating based on 100+ reviewsThis serum is highly effective for mature, dry, and aging skin, with users frequently reporting improvements in texture, firmness, and radiance. Based on limited data, the product is praised for visibly reducing fine lines and hyperpigmentation, leaving the complexion plumper and more even-toned. Some users note a tacky feel after application and that results require patience, while the high price point is a common concern.
Highlights
Improves skin texture Mostly Mentioned
- “Skin feels smoother”
- “texture has improved”
- “skin is plumper”
High price point Mostly Mentioned
- “Very pricey”
- “could not have afforded”
- “worth every penny but expensive”
Boosts skin radiance Often Mentioned
- “Skin looks glowing”
- “complexion more radiant”
- “beaming skin”
Reduces fine lines Often Mentioned
- “Laugh lines less obvious”
- “wrinkles less visible”
- “targets fine lines”
Deeply hydrating Sometimes Noted
- “Instant hydration boost”
- “sealing in moisture”
- “great for dehydrated skin”
Gentle formula Sometimes Noted
- “Great on sensitive skin”
- “no breakouts”
- “non-irritating”
Requires patience Sometimes Noted
- “Takes weeks to notice”
- “not instant results”
- “cumulative improvements”
Tacky skin feel Sometimes Noted
- “Sticky for 30 mins”
- “tacky feel after application”
Limited care feeling Rarely Noted
- “Doesn't feel 'creamed'”
- “need extra moisturizer”
- “not enough for some”
Sources: lovi.care, bioeffect.com, dermstore.com, whowhatwear.com, joannaczech.com, katiesnooks.com, and more
Questions and answers
What makes BIOEFFECT EGF Power Serum a great fit for dry sensitive skin?
This serum is a great fit because it offers wonderful skin regeneration with growth factors to improve elasticity, while glycerin and sodium hyaluronate provide moderate hydration and barley extract helps repair your skin barrier. It has a very safe profile and is very unlikely to cause irritation since it lacks harsh ingredients.
Which ingredients make this serum a good fit for dry sensitive skin?
This serum is a great fit because Glycerin and Sodium Hyaluronate provide moderate hydration while Hordeum Vulgare Seed Extract helps repair the skin barrier. Additionally, Rh-Oligopeptide-1 and Kgf Barley Sh-Polypeptide-3 offer excellent skin regeneration to improve elasticity and reduce fine lines without causing irritation.
What does EGF do for dry sensitive skin?
EGF helps calm dry sensitive skin by supporting skin repair and renewal, though it may need to be paired with rich moisturizers and soothing ingredients to properly comfort very dry or reactive areas.
What does Hyaluronic Acid do for dry sensitive skin?
Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Journal of Drugs in Dermatology, 2011Dermatology and Therapy, 2021
Where does this serum go in a skincare routine for dry sensitive skin?
This serum goes in your evening routine after your toner and before your moisturizer. Treatments are placed in the evening for simplicity and extra safety around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first in your evening routine, as its gentle ingredients and excellent safety profile mean it is unlikely to cause irritation. Following it with a moisturizer helps keep dry sensitive skin comfortable.
How often should I use this serum?
This treatment serum works best in your evening routine for simplicity and extra safety around sun exposure. It is a great fit for your dry and sensitive skin, and you can safely use it every evening to help improve elasticity and reduce fine lines without irritation.
Can this serum clog pores, cause breakouts or purging for dry sensitive skin?
This serum is unlikely to clog pores or cause breakouts for dry sensitive skin because it is free of heavy, harsh ingredients that typically trigger irritation or congestion. Glycerin and sodium hyaluronate help keep skin hydrated without leaving a heavy layer.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Fibrin-bound keratinocyte growth factor released via cell-mediated degradation significantly enhanced wound closure in a hybrid model of full-thickness wound healing in athymic mice compared to topical KGF.
The American Journal of Pathology, 2005A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide.
Journal of Cosmetic Dermatology, 2007N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers.
Advanced Pharmaceutical Bulletin, 2016Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants.
Journal of Cosmetic and Laser Therapy, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012
Ingredients
Glycerin, Water, Sodium Citrate, Acetyl Glucosamine Nag, Isopentyldiol, Phenoxyethanol, Sodium Chloride, Sodium Hyaluronate, Citric Acid, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1, Kgf Barley Sh-Polypeptide-3
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.