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Vitamin A and acetyl hexapeptide-3

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Vitamin A and acetyl hexapeptide-3: keep them apart

Keep them apart

Use them at different times of day, applying the peptide product in the morning and the vitamin A at night, to avoid extra skin irritation. Vitamin A and acetyl hexapeptide-3 both push your skin to work hard on renewal, which can cause redness and stinging when mixed together. You can fix this by using a gentler vitamin A strength or by switching to alternate nights.

Vitamin A products

Acetyl hexapeptide-3 products

Questions and answers

Can you use vitamin A and acetyl hexapeptide-3 together?

Keep vitamin A and acetyl hexapeptide-3 apart because combined stimulation may increase irritation, so try alternating their usage with a retinoid in the evening and peptides in the morning.

Which goes first, vitamin A or acetyl hexapeptide-3?

Keep vitamin A and acetyl hexapeptide-3 apart in your routine because combined stimulation may increase irritation. Alternate your usage by applying the retinoid in the evening and peptides in the morning.

Are vitamin A and acetyl hexapeptide-3 good for sensitive skin?

Keep vitamin A and acetyl hexapeptide-3 apart in your routine because combining them may increase irritation, so you can alternate usage by applying your retinoid in the evening and peptides in the morning.

Research on vitamin A and acetyl hexapeptide-3

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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