Simple and Natura Bissé are distinct skincare options from British and Spanish origins respectively. Simple is known for gentle moisturizers, makeup removers, cleansers, and toners crafted with niacinamide and glycerin , which suit acne-prone skin and skin with dark spots best. Conversely, the brand from Spain is loved for luxurious moisturizers and advanced formulas that suit mature, dry, and sensitive skin best. While both offer nourishing care, they differ through their specific formulations and ideal skin types.
Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.
en.wikipedia.org sec.gov prnewswire.com simple.co.uk
Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..
naturabisse.com tracxn.com
This page compares some of the most popular Simple and Natura Bissé products; for every product of both brands, with a fit score for your own skin, use the Lovi app .
Popular Simple vs Natura Bissé products
Questions and answers
Simple or Natura Bissé: which is better?
What is the difference between Simple and Natura Bissé?
Simple offers a range of fragrance-free products best suited for acne-prone skin, oily skin, and skin with dark spots, with Lovi fit levels ranging from Low to Superior. In contrast, Natura Bissé features the Diamond Extreme moisturizer, which includes fragrance and achieves a Superior Lovi fit for mature skin.
Simple or Natura Bissé: which moisturizer is better?
Simple offers lightweight and value-friendly moisturizers with average Lovi fit levels for dry skin, while Natura Bissé Diamond Extreme achieves a High fit level for dry skin and a Superior fit level for mature skin. Glycerin helps provide hydration in the products on this page.
Clinical, Cosmetic and Investigational Dermatology, 2017
Which is more affordable, Simple or Natura Bissé?
Simple offers value-friendly moisturizers, while Natura Bissé is a luxury brand.
Which causes fewer breakouts, Simple or Natura Bissé?
Simple features fragrance-free options that reviewers say can sometimes cause breakouts, while Natura Bissé has too few reviews on this page to compare. Glycerin helps maintain skin hydration across Simple products on this page.
Clinical, Cosmetic and Investigational Dermatology, 2017
Which brand was founded earlier and in which country?
Simple was founded earlier in 1960 in the United Kingdom, whereas Natura Bissé was founded in 1979 in Spain.
Do both Simple and Natura Bissé products contain fragrance?
Simple products on this page list no fragrance, whereas Natura Bissé includes fragrance in its Diamond Extreme moisturizer.
Which Simple product has a Superior fit level for mature skin?
Simple Kind to Skin Soothing Facial Toner has a Superior fit level for mature skin.
3 more questions
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Niacinamide · The British Journal of Dermatology, 2002 Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation
Niacinamide · Antioxidants, 2021 Topical use of dexpanthenol in skin disorders
Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002 Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016 The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
28 more studies
Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021 Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling
Leontopodium alpinum leaf extract flower · Genes, 2020 Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells
Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012 A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017 Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024 Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation
Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019 Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020 High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel leaf water · Phytochemistry, 2001 Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function
Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022 Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment
Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009 Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015 Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial
Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020 Whitening effect of alpha-bisabolol in Asian women subjects
Bisabolol · International Journal of Cosmetic Science, 2010 Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers
Sodium ascorbyl phosphate · Drug Research, 2017 Understanding Solar Skin Elastosis-Cause and Treatment
Witch hazel leaf water · Journal of Cosmetic Science, 2018 Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis
Borago officinalis seed oil · Lipids, 2020 Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998 Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025 Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects
Sodium ascorbyl phosphate · Experimental Dermatology, 2012 Formulation and evaluation of exotic fat based cosmeceuticals for skin repair
Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008 Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate · Scientific Reports, 2025 Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum
Caprylic capric triglyceride · Life, 2023 Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial
Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021 Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study
Sodium laureth sulfate · International Journal of Pharmaceutics, 2026 A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study
Saccharide isomerate · The Journal of Dermatological Treatment, 2025 Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial
Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025 Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Saccharide isomerate · Journal of Cosmetic Dermatology, 2023 Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
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Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
Nadia Kapleva, MS
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
Alexey Shagraev, PhD
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
Aishani Shah, MD
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
Asya Zubkova, MS
Medical Board
Cosmetic chemist, SCS, IFSCC member
Hanna Kurets, MD
Medical Board, Medical Advisor
Dermatology MD
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist