A+ vs Sesderma
A+ and Sesderma are established skincare brands founded in 1990 and 1989, respectively. A+ is beloved for its gentle moisturizers and thoughtfully calibrated formulas that suit sensitive skin best and reliably support daily moisture balance, with the 345 Relief Cream standing out for acne-prone skin. Meanwhile, the Spanish brand is known for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds that refine skin texture and promote a radiant complexion. While both serve sensitive skin, the latter additionally suits hyperpigmented and aging skin types best, offering targeted solutions such as the Azelac RU Serum for acne-prone skin.
A+ is an Indian skincare brand founded in 1990.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular A+ and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
A+ or Sesderma: which is better?
Sesderma offers a High Lovi fit for acne-prone skin and skin with dark spots with its Azelac RU Serum, while A+ products on this page show Average or Low fits across skin types. Azelaic acid helps in the treatment of acne vulgaris.
What is the difference between A+ and Sesderma?
Sesderma achieves a High Lovi fit for skin with dark spots with its Azelac RU Serum, whereas A+ products on this page get an Average fit for those concerns. Additionally, the products on this page from A+ list no fragrance, while Sesderma includes fragrance in its serum.
Which is more affordable, A+ or Sesderma?
This page does not provide pricing or affordability information for either A+ or Sesderma.
Which causes fewer breakouts, A+ or Sesderma?
For acne-prone skin, Sesderma has a High Lovi fit with Azelac RU Serum, whereas A+ products on this page have an Average fit. Azelaic acid helps manage acne vulgaris.
Where were A+ and Sesderma founded?
A+ was founded in India, and Sesderma was founded in Spain.
Which brand offers products with no fragrance listed in their ingredients?
A+ offers products with no fragrance listed in their ingredients, as every product on this page from the brand is formulated without fragrance.
How does the Lovi fit level for combination skin compare between A+ and Sesderma's featured products?
For combination skin, Sesderma's Azelac RU Serum achieves a High Lovi fit level, whereas A+'s 345 Relief Cream reaches only a Low fit level. Sesderma's product also contains fragrance, while A+'s product lists no fragrance.
Research behind their key ingredients
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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