Vitamin A and palmitoyl tripeptide-1
Keep them apart
Use them at different times of day by applying vitamin A at night and palmitoyl tripeptide-1 in the morning to prevent extra skin irritation. Both active ingredients push your skin to renew itself quickly, which can easily lead to redness and sensitivity when used together. You can fix this by using a gentler vitamin A product or simply keeping them in separate daily routines.
Vitamin A products
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Bio-Oil
Skincare Oil
€14.65
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ZO Skin Health
Exfoliating Polish
€155.00
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Peter Thomas Roth
Instant FIRMx Eye Temporary Eye Tightener
€11.90
- Peter Thomas Roth Instant FirmX Temporary Face Tightener
-
Augustinus Bader
The Cream
€229.99
-
U Beauty
Resurfacing Compound
€226.80
- Philosophy Hope In A Jar
- SkinMedica TNS Eye Repair
- Dermalogica Multivitamin Power Recovery Masque
- BYOMA Sensitive Retinol Oil
- NatureWell Extra Virgin Coconut Oil Moisturizing Cream
- Murad Essential-C Cleanser
Palmitoyl tripeptide-1 products
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The Ordinary
Multi-Peptide + Copper Peptides 1% Serum
€30.99
-
The Ordinary
Multi-Peptide + HA Serum
€17.89
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Medik8
Liquid Peptides
€109.17
-
Shiseido
Benefiance Wrinkle Smoothing Eye Cream
€59.95
-
Clinique
Smart Clinical Repair Wrinkle Correcting Serum
€88.99
- Alastin Skincare Regenerating Skin Nectar
-
The Ordinary
Matrixyl 10% + HA
€11.96
-
ZO Skin Health
Daily Power Defense
€230.00
- The INKEY List Collagen Peptide Serum
- Alastin Ultra Nourishing Moisturizer
-
DRMTLGY
Needle-less Serum
€59.31
-
Valmont
Prime Renewing Pack
€330.00
Questions and answers
Can you use vitamin A and palmitoyl tripeptide-1 together?
No, you should keep vitamin A and palmitoyl tripeptide-1 apart in your routine because combined stimulation may increase irritation, though you can use the retinoid at night and peptides in the morning. Mary Kay Timewise Night Solution contains both ingredients.
Which goes first, vitamin A or palmitoyl tripeptide-1?
Keep vitamin A and palmitoyl tripeptide-1 apart by using them at different times of day, such as your retinoid at night and peptides in the morning. Combining them in the same routine may increase your risk of skin irritation.
Are vitamin A and palmitoyl tripeptide-1 good for sensitive skin?
Vitamin A and palmitoyl tripeptide-1 should be kept apart to avoid increased irritation on sensitive skin, so use them at different times like PM retinoid and AM peptides. You may find them together in finished products like Mary Kay Timewise Night Solution.
Research on vitamin A and palmitoyl tripeptide-1
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Encapsulation and controlled release of retinol from silicone particles for topical delivery
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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