Sesderma and MAC are distinct beauty houses, with the former being a Spanish skincare brand founded in 1989 and the latter being a Canadian skincare brand founded in 1984. Sesderma is beloved for its advanced serums and meticulously engineered formulas, while the second brand is known for offering reliable moisturizers and makeup removers crafted from carefully balanced formulas. The first brand suits sensitive, hyperpigmented, and aging skin types best through botanical extracts and active compounds, whereas MAC suits balanced skin best, supported by gentle and effective ingredients. They differ because the Spanish label relies on synergistic active ingredients to refine skin texture and promote a radiant complexion, while the Canadian label provides a calm and measured foundation for daily maintenance.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
This page compares some of the most popular Sesderma and MAC products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
MAC is a better fit for dry sensitive skin because the products on this page achieve a High fit level for that type, whereas Sesderma achieves only a Low fit level there. Reviewers mention that MAC offers popular lightweight moisturizers, but the brand's products on this page all contain fragrance.
What is the difference between Sesderma and MAC?
Sesderma offers a serum with a High Lovi fit for acne-prone skin and dark spots, whereas MAC provides moisturizers and cleansers that achieve High Lovi fits for dry sensitive skin. Reviewers note that MAC products often have a strong fragrance, and Sesderma's serum on this page also contains fragrance.
MAC is noted for having a high price point, while Sesderma is not described as such on this page. Lovi does not provide a price comparison between the two brands.
Which causes fewer breakouts, Sesderma or MAC?
For acne-prone skin, Lovi rates Azelac RU Serum by Sesderma as High, while the moisturizers and cleansers on this page by MAC are rated Average. MAC products on this page may cause irritation due to strong fragrance, which is a common concern among reviewers.
Which brand offers products with a High Lovi fit for dry skin, Sesderma or MAC?
MAC offers products with a High Lovi fit for dry skin, specifically through the Mineralize Timecheck Lotion and Hyper Real Fresh Canvas Cleansing Oil on this page. In contrast, Sesderma has a Low fit for dry skin with its Azelac RU Serum.
How does the founding date and country of origin compare between Sesderma and MAC?
Sesderma was founded in Spain in 1989, whereas MAC was founded in Canada in 1984.
Do both Sesderma and MAC products contain fragrance according to the page?
Yes, both brands include fragrance in all of the products listed on this page, as every single item from both Sesderma and MAC contains fragrance.
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Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
