SkinMedica HA5® for mature skin
Hyaluronic Acid
Hydrolyzed CollagenAverage
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for mature skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your normal skin due to the presence of hyaluronic acid and hydrolyzed collagen, which hydrate and plump the skin. Glycerin further supports this humectant action, making it highly suitable for your skin type.
- While it provides general hydration benefits, the concentrations of these ingredients are not specialized for targeting wrinkles and fine lines, which is your main goal.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.7Overall rating based on 2.0k+ reviewsBased on a very large amount of data, this product is highly effective for dry, dehydrated, and aging skin, providing deep and lasting moisture. Users frequently observe a plumper complexion and smoother skin texture, with many noting a reduction in fine lines. A common concern is the high price point, and some users find the need for damp application to be a minor inconvenience.
Highlights
Deeply hydrates skin Mostly Mentioned
- “My skin felt hydrated throughout the day and night!”
- “Delivers a surge of moisture that leaves my skin refreshed.”
- “Super hydration throughout the day, skin feels great.”
- “Keeps that extra moisture in that is definitely needed.”
Plumps and smooths Often Mentioned
- “Plumps and smoothes my skin.”
- “My skin is so soft and flawless in the morning.”
- “Left my skin plump which in return reduced fine lines.”
- “Noticed that my skin became instantly soft and smooth.”
High price point Often Mentioned
- “Efficient serum but expensive.”
- “The product is expensive.”
- “It is expensive! But it's worth it.”
- “Falls under the upper price category.”
Lightweight, non-greasy feel Sometimes Noted
- “Absorbed nicely into the skin with no oily feeling.”
- “Non-greasy and doesn't leave a film.”
- “This is not heavy at all.”
- “Blends in well and isn't greasy.”
Reduces fine lines Sometimes Noted
- “Helps decrease the appearance of fine lines and wrinkles.”
- “Reduced the appearance of wrinkles, and enhanced skin texture.”
- “Smooths out the appearance of fine lines and wrinkles.”
- “Visibly smooth the appearance of fine lines.”
Requires damp application Sometimes Noted
- “Works better for me with wet fingers when applying.”
- “Be sure to wet your fingers before applying as the instructions state.”
- “HA5 is water-loving, so wet your fingertips prior to applying.”
- “Apply to clean, slightly damp skin.”
Formula consistency changes Rarely Noted
- “Did they change the formula in the last 2-3 years?”
- “Now it feels a little thicker.”
- “I don't feel like it's as amazing as it was.”
- “Reformulation costs meaningfully more than the original.”
Sources: lovi.care, lovelyskin.com, dermstore.com, walmart.com, dermapproved.com, thebusymommylife.com, and more
Questions and answers
How well does SkinMedica HA5 work for mature skin?
SkinMedica HA5 provides moderate hydration for mature skin with ingredients like hyaluronic acid and hydrolyzed collagen, but it is not specialized for targeting wrinkles and fine lines. A product of this type needs effective anti-aging ingredients like peptides and skin-repairing components to properly address mature skin concerns.
Clinical, Cosmetic and Investigational Dermatology, 2017Dermatologic Therapy, 2022
Which ingredients make this treatment a good fit for mature skin?
Hyaluronic acid and hydrolyzed collagen make this treatment a good fit by hydrating and plumping your mature skin, while glycerin further supports this moisture. However, because mature skin needs specialized care for wrinkles and fine lines, a product of this type needs effective anti-aging ingredients, peptides, and skin-repairing components to provide optimal benefits.
Clinical, Cosmetic and Investigational Dermatology, 2017Dermatologic Therapy, 2022
What does Water do for mature skin?
Water helps keep mature skin hydrated, which significantly lowers the severity of wrinkles and maintains elasticity. Because aging skin often loses moisture and firmness, it needs hydrating ingredients like glycerin and hyaluronic acid to stay plump and smooth.
What does Hyaluronic Acid do for mature skin?
Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024
Where does this treatment go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing and toning, followed by a moisturizer. Mature skin needs a treatment with specialized ingredients targeting wrinkles and fine lines, such as potent anti-aging peptides or antioxidants.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol, applying it after your retinol has fully absorbed into the skin. This product is unlikely to cause irritation because it contains gentle, hydrating ingredients.
How often should I use this treatment?
This treatment is used in the evening routine, applied once a day. Using it daily helps keep the skin hydrated and smooth, though mature skin also needs specialized anti-wrinkle ingredients.
Health Science Reports, 2021Journal of Drugs in Dermatology, 2015
Can this treatment clog pores, cause breakouts or purging for mature skin?
This treatment is unlikely to clog pores or cause breakouts for mature skin because it lacks harsh ingredients and has a very safe formula. A product for this skin needs nourishing ingredients and targeted treatments that smooth fine lines while keeping the skin soft and hydrated.
Can I use this treatment around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, as its safe formula is unlikely to cause irritation. Because the skin around the eyes is exceptionally thin, gentle and hydrating products of this type work well to keep it soft and smooth.
Surgical and Radiologic Anatomy, 2002Clinical, Cosmetic and Investigational Dermatology, 2017
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023
Why other moisturizers fit mature skin better
An oil/water emulsion containing 10% Argireline reduced wrinkle depth up to 30% and inhibited neurotransmitter release in healthy women volunteers compared to baseline.
International Journal of Cosmetic Science, 2002Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013
Ingredients
Water, Hyaluronic Acid, Hydrolyzed Collagen, Glycerin, Dimethicone, Caprylyl Glycol, Phenoxyethanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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