Peach Slices Redness Relief Calming Cream for mature skin

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Questions and answers

What the research says

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers.

  Molecules, 2024

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.

  Arzneimittel-Forschung, 2000

• Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.

  Auris, Nasus, Larynx, 2020

• Spinacia oleracea extract loaded ultra-high pressure homogenized emulsion significantly decreased skin melanin, spot count, and spot percentage area while improving skin hydration in 13 healthy female volunteers over 12 weeks.

  Journal of Cosmetic Dermatology, 2022

• Spinach thylakoid extracts protected human THP-1 cells against reactive oxygen species without cytotoxicity, provided synergetic UV protection when combined with sunscreen, and repaired UV damages on engineered human skin when mixed with a neutral cream.

  Journal of Cosmetic Dermatology, 2019

• Topical and oral administration of natural antioxidant from spinach significantly reduces skin papilloma multiplicity in female hemizygous Tg.AC mice treated with 12-O-tetradecanoylphorbol-13-acetate (TPA) compared to the TPA-only control group.

  Toxicology Letters, 2001

• Supplementation of a broad-spectrum sunscreen with Spirulina and dimethylmethoxy chromanol significantly improved skin pigmentation, reduced collagen degradation, and enhanced net elasticity in 44 healthy subjects after 84 days compared to sunscreen alone.

  European Journal of Pharmaceutical Sciences, 2017

• Spirulina and its bioactive compounds provide antioxidant, anti-aging, and photoprotective benefits in cosmetic formulations by promoting skin hydration, reducing wrinkles, enhancing collagen production, and protecting skin cells from UV-induced apoptosis.

  Biotech), 2025

• Topical application of a gel formulated with spray dried Spirulina protein and muscadine grape pomace polyphenol particles mitigated oxidative protein damage, inflammation, and skin barrier disruption in ex vivo human biopsies exposed to diesel engine exhaust.

  Antioxidants, 2023

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties.

  Skin Pharmacology and Physiology, 2023

• Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models.

  Drug Discovery Today, 2017

• A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation.

  Saudi Pharmaceutical Journal, 2024

Why other moisturizers fit mature skin better

• Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.

  International Journal of Medical Sciences, 2021

• Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement.

  Nanomaterials, 2024

• Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.

  Journal of Cosmetic Dermatology, 2026

Ingredients

Water, Propanediol, Caprylic Capric Triglyceride, Glycerin, Butylene Glycol Dicaprylate Dicaprate, 1,2-Hexanediol, Hydrogenated Polydecene, Helianthus Annuus Seed Oil Sunflower Seed Oil, Polyglyceryl-3 Methylglucose Distearate, Panthenol, Jojoba Seed Oil, Spirulina Platensis Extract, Rhodomyrtus Tomentosa Fruit Extract, Artemisia Vulgaris Extract, Centella Asiatica Extract, Brassica Oleracea Italica Extract, Curcuma Longa Root Extract, Sodium Polyacryloyldimethyl Taurate, Sorbitan Olivate, Arginine, Melia Azadirachta Leaf Extract, Spinach Leaf Extract, Glyceryl Stearate, Sorbitan Sesquioleate, Butylene Glycol, Dextrin, Allantoin, Carthamus Tinctorius Flower Extract, Gardenia Florida Fruit Extract, Melia Azadirachta Flower Extract, Cetearyl Olivate, Carbomer, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Caprylyl Glycol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.