NATURIUM Multi-Peptide Moisturizer for combination skin
Multi-Peptide Blend
3-O-Ethyl Ascorbic Acid Ethylated Vitamin C
Panthenol Vitamin B5
Squalane
Niacinamide
High
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
A great choice for combination skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your combination skin, the presence of niacinamide and sodium hyaluronate supports barrier repair and hydration, while glycerin and squalane offer excellent moisturizing benefits to enhance barrier resilience.
- The formula provides general skincare benefits like hydration and soothing, which can be supportive for managing oily shine on combination skin.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of prohibited or harsh ingredients.
How to apply
- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
People Say
★4.5Overall rating based on 600+ reviewsThis moisturizer is highly praised for its lightweight and absorbent texture, making it suitable for oily and combination skin types. It effectively plumps fine lines and improves skin texture, providing a smooth base for makeup. However, users with very dry skin may find it insufficient for their hydration needs and might require additional layering. A small number of reviews mention issues with the pump packaging or experiencing breakouts.
Highlights
Lightweight & Absorbent Mostly Mentioned
- “glides on”
- “sinks effortlessly”
- “non-greasy”
- “drinks it up”
Makeup Compatibility Often Mentioned
- “perfect under makeup”
- “acts like a primer”
- “no pilling”
- “smooth canvas”
Sanitary Packaging Sometimes Noted
- “love the pump”
- “hygienic”
- “airless pump”
- “easy to dispense”
Skin Texture & Plumping Sometimes Noted
- “plumps fine lines”
- “smoother skin”
- “glowy finish”
- “bouncy feel”
Value for Money Sometimes Noted
- “affordable”
- “great ingredients for price”
- “beats high-end”
- “budget friendly”
Not hydrating enough Sometimes Noted
- “too light for dry skin”
- “need more moisture”
- “felt tight later”
- “better for summer”
Breakouts/Irritation Rarely Noted
- “caused cystic acne”
- “tiny red bumps”
- “reaction to niacinamide”
- “broke me out”
Packaging malfunctions Rarely Noted
- “pump arrived broken”
- “stopped pumping”
- “had to cut open”
- “mechanism failed”
Pilling issues Rarely Noted
- “pills with toner”
- “rolled off skin”
- “clumped with serum”
- “didn't layer well”
Small quantity Rarely Noted
- “runs out fast”
- “tube is small”
- “wish it was bigger”
- “finished in weeks”
Sources: lovi.care, naturium.com, target.com, influenster.com, spacenk.com, skinsort.com, and more
Questions and answers
What makes Naturium Multi-Peptide Moisturizer a great fit for combination skin?
This moisturizer is a great fit because ingredients like niacinamide and sodium hyaluronate help keep skin hydrated and repair the skin barrier. Glycerin and squalane provide great moisturizing benefits that make the skin soft, while the formula helps manage oily shine and has an excellent safety profile without harsh ingredients.
Which ingredients make this cream a good fit for combination skin?
This cream is a great fit for combination skin because it contains niacinamide and sodium hyaluronate to support moisture and barrier repair, alongside glycerin and squalane to keep the skin soft. These ingredients provide balanced hydration while helping to manage oily shine safely without irritation.
What do Peptides do for combination skin?
Peptides help combination skin by supporting firmness, smoothing out wrinkles, and improving hydration without feeling heavy. They work by encouraging collagen production, which may help keep the skin looking smooth and bouncy.
International Journal of Molecular Sciences, 2025International Journal of Molecular Medicine, 2017
What does 3-O-Ethyl Ascorbic Acid do for combination skin?
3-O-Ethyl Ascorbic Acid helps brighten combination skin and may reduce dark spots and uneven tone. Laser pretreatment can further boost how well this vitamin C derivative sinks into the skin.
Where does this cream go in a skincare routine for combination skin?
This cream goes as the third step in your morning routine after your cleanser and hydrating toner, and as the last step in your evening routine after your cleanser, toner, and treatment. It is a great fit for your skin because ingredients like niacinamide, sodium hyaluronate, glycerin, and squalane support hydration and barrier repair while helping manage oily shine.
Clinical, Cosmetic and Investigational Dermatology, 2017Scientific Reports, 2024
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying the moisturizer either before or after your retinol treatment to help keep your skin comfortable and hydrated. Using a barrier-enhancing moisturizer alongside retinoids is unlikely to cause irritation and may support your skin during treatment.
How often should I use this cream?
You can use this cream twice daily as part of your morning and evening routine to keep your skin hydrated and supported. Regular application helps maintain moisture and is unlikely to cause irritation.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for combination skin?
This cream is unlikely to cause breakouts or irritation for combination skin, as it has a very safe profile and lacks harsh ingredients. It also helps manage oily shine while keeping your skin hydrated.
Clinical, Cosmetic and Investigational Dermatology, 2017Scientific Reports, 2024
Can I use this cream around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, as its gentle ingredients are suitable for thinner skin areas. The formula provides good hydration and has an excellent safety profile, making it unlikely to cause irritation.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and stearyl alcohol are fatty alcohols, which soften the skin.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.
Scientific Reports, 2024Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.
Journal of Pharmacy & Pharmaceutical Sciences, 2015A topical serum with a peptide blend showed superior or comparable skin recovery to a moisturizer following fractional CO2 laser and radiofrequency microneedling in Asian subjects.
Dermatology and Therapy, 2026Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005
Ingredients
Water, Glycerin, Dimethicone, Jojoba Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Octenylsuccinate Starch, Hydroxyacetophenone, Stearic Acid, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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