Eucerin Q10 Anti-Wrinkle + Pro-Retinol Night Cream for dry sensitive skin
Ubiquinone
Pro-Retinol
Retinyl Palmitate
Shea Butter
Macadamia Ternifolia Seed Oil
Average
- HighDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry sensitive skin; other moisturizers fit it better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- Colloids and Surfaces. B, Biointerfaces, 2011
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing and anti-aging benefits for your dry and sensitive skin, as glycerin and shea butter provide essential hydration and emollient properties, while retinyl palmitate works to minimize fine lines.
- While the formula is generally supportive for dry or flaky skin, it lacks specialized ingredients to directly target and resolve significant dryness or flakiness.
- The product is safe for your skin, with no reported risks of irritation due to the absence of harsh or prohibited ingredients.
How to apply
- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
People Say
★4.4Overall rating based on 10.0k+ reviewsBased on a very large amount of data, this night cream is highly recommended for sensitive and dry skin, offering significant hydration and a gentle approach to reducing fine lines. While most users appreciate its moisturizing properties and improvement in skin texture, some find the scent unpleasant and the formula too rich for oily skin or prefer more potent anti-aging effects.
Highlights
Gentle on sensitive skin Mostly Mentioned
- “No irritation or redness even on my reactive skin”
- “Perfect for sensitive skin that can't handle strong retinol”
- “Does not sting or burn like other anti-aging creams”
Deeply moisturizing Often Mentioned
- “Wake up with incredibly soft and plump skin”
- “Rich texture that hydrates dry patches overnight”
- “Leaves my face feeling nourished but not greasy”
Good absorption Sometimes Noted
- “Absorbs quickly despite being a thick cream”
- “Sinks in well, doesn't sit on top of skin”
- “Non-greasy finish that doesn't stain pillowcases”
Great value Sometimes Noted
- “Beats expensive luxury creams for a fraction of the price”
- “Affordable enough to use generously on neck and chest”
- “High quality ingredients for a drugstore price”
Improves skin texture Sometimes Noted
- “Skin feels smoother and firmer in the morning”
- “Helps with crepey texture on my neck”
- “Softens fine lines around the eyes and mouth”
Unpleasant scent Sometimes Noted
- “Has a weird, sour chemical smell”
- “Smells like old ingredients or 'science'”
- “Unscented but has a funky natural odor”
Mild/slow results Rarely Noted
- “Didn't see dramatic changes in deep wrinkles”
- “Good moisturizer but weak anti-aging effects”
- “Takes months to see a visible difference”
Too thick/rich Rarely Noted
- “Feels a bit heavy and waxy on the skin”
- “Caused some congestion on my oily T-zone”
- “Too thick for summer or humid weather”
Yellow discoloration Rarely Noted
- “The cream has a yellow tint that can look odd”
- “Stained my white pillowcase slightly”
- “Color looks off, like it oxidized”
Sources: lovi.care, iherb.com, amazon.com, walmart.com, cvs.com, kroger.com, and more
Questions and answers
How well does Eucerin Q10 Anti-Wrinkle + Pro-Retinol Night Cream work for dry sensitive skin?
This cream works moderately well for dry sensitive skin by providing basic hydration and anti-aging benefits, though it is unlikely to resolve significant dryness on its own. To care for dry skin, a product of this type needs deep-acting moisturizing ingredients and soothing agents that offer intense hydration and support the skin barrier.
Which ingredients make this cream a good fit for dry sensitive skin?
Glycerin and shea butter make this cream a good fit by providing essential moisture and keeping your skin soft, while retinyl palmitate helps smooth fine lines without causing irritation. To truly thrive, dry and sensitive skin needs a product of this type to include soothing ingredients that deeply nourish, support the skin barrier, and deliver intense hydration without any risk of irritation.
What does Coenzyme Q10 do for dry sensitive skin?
Coenzyme Q10 helps dry sensitive skin by providing antioxidant effects and boosting cellular energy to protect against daily stress and reduce signs of aging. It replenishes surface and deeper hydration levels while maintaining a safe and gentle profile for easily irritated skin.
BioFactors, 2015The Journal of Clinical and Aesthetic Dermatology, 2024
What does Pro-Retinol do for dry sensitive skin?
Pro-retinol helps smooth out lines and even out skin tone while being gentle enough for dry, sensitive skin. It works gradually to improve the look of aging skin and is unlikely to cause heavy irritation or peeling.
International Journal of Cosmetic Science, 2024The British Journal of Dermatology, 2010
Where does it go in a skincare routine for dry sensitive skin?
This treatment goes in the evening routine after your toner and before your moisturizer. A product of this type needs rich hydrators and soothing barrier ingredients to properly care for dry skin.
Can I use this cream with vitamin C, and in what order?
How often should I use it?
This cream is safe for your dry sensitive skin and can be used in your evening routine as a treatment, though a product of this type needs specialized hydrating ingredients to directly target and resolve significant dryness or flakiness.
Journal of Cosmetic Dermatology, 2020Journal of Drugs in Dermatology, 2015
Can this cream clog pores, cause breakouts or purging for dry sensitive skin?
This cream is unlikely to clog pores or cause breakouts for your dry sensitive skin, as it has a safe formula without harsh ingredients that cause irritation. However, because it lacks specialized ingredients to directly target significant dryness, a product of this type needs richer hydrators and barrier-repairing ingredients to fully comfort very dry skin.
Can I use it around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, but it is best suited for facial use since skin thickness varies greatly across the body and the eyelid is the thinnest area. While it is safe and unlikely to cause irritation, a product for very thin or large areas may need specialized hydrating ingredients to fully resolve significant dryness or flakiness.
Surgical and Radiologic Anatomy, 2002Colloids and Surfaces. B, Biointerfaces, 2011
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and stearyl alcohol are fatty alcohols, which soften the skin.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Retinyl palmitate-loaded non-ionic lamellar liquid crystalline systems provided a significant reduction of orbicular wrinkles in human volunteers compared to systems without retinyl palmitate.
Colloids and Surfaces. B, Biointerfaces, 2011Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism.
BioFactors, 2008Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects.
Colloids and Surfaces. B, Biointerfaces, 2023Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects.
Antioxidants, 2021Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question.
The Journal of Clinical and Aesthetic Dermatology, 2021A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women.
The British Journal of Dermatology, 2010A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation.
International Journal of Cosmetic Science, 2024A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.
International Journal of Cosmetic Science, 2025
Why other moisturizers fit dry sensitive skin better
Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021
Ingredients
Water, Glycerin, Ethylhexyl Cocoate, Cetyl Alcohol, Hydrogenated Coco-Glycerides, Stearyl Alcohol, Butylene Glycol, Caprylic Capric Triglyceride, Butyrospermum Parkii Butter Shea Butter, Glyceryl Stearate Citrate, Macadamia Ternifolia Seed Oil, Octyldodecanol, Ubiquinone, Retinyl Palmitate, Tocopherol, 1,2-Hexanediol, Dehydroacetic Acid, Carbomer, Sodium Hydroxide, Trisodium Edta
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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