Eucerin Hyaluron-Filler Epigenetic Serum for combination skin
Glycerin
Hyaluronic AcidAverage
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for combination skin; other moisturizers fit it better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- The Journal of Dermatological Treatment, 2017
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your combination skin, as glycerin and hyaluronic acid provide hydration without exacerbating oiliness. Panthenol further supports skin barrier function and hydration.
- This serum offers general skincare benefits, addressing oily shine by providing essential hydration.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients.
How to apply
- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
People Say
★4.5Overall rating based on 1.6k+ reviewsBased on a very large amount of data, users consistently report that the serum provides an immediate boost of hydration, leaving skin feeling significantly smoother, softer, and more radiant. While many observed a reduction in fine lines and a "plumped" effect within a few weeks, a small minority experienced skin irritation or felt the anti-aging results were not visible enough to justify the price.
Highlights
Lightweight, fast absorption Mostly Mentioned
- “texture is lightweight and absorbs rapidly without leaving any residue”
- “soaks into skin lovely... doesn't feel greasy”
- “light gel texture that transforms almost into water”
Layers well Often Mentioned
- “layers really well under the makeup”
- “didn't pill under my moisturizer”
- “makes a great base under make-up”
Smoother, plumper skin Often Mentioned
- “skin feels plumped and rejuvenated”
- “texture of my skin was smoother”
- “face feels firmer and appears more youthful”
Pleasant, subtle scent Sometimes Noted
- “fragrance is subtle and fresh”
- “smell is really refreshing and nice”
- “scent is very light... not overpowering”
Radiant, fresh glow Sometimes Noted
- “makes your skin look fresh and glowy”
- “regained the sort of translucent quality”
- “skin feels more radiant”
High price point Sometimes Noted
- “slightly pricey but does what it says”
- “expensive for the amount you get”
- “not worth the full price tag”
Allergic reactions Rarely Noted
- “terrible reaction... requiring prescription-level antihistamines”
- “caused irritation and breakouts”
- “left my skin red and itchy”
No visible results Rarely Noted
- “haven't seen any massive difference”
- “don't really think it is anything special”
- “yet to see any results in appearance”
Scent too strong Rarely Noted
- “smell is a bit too strong for me”
- “has a slight fragrance... sensitive skin might not like”
- “perfume is quite noticeable”
Sources: lovi.care, boots.com, superdrug.com, lookfantastic.com, sephora.co.uk, hometesterclub.com, and more
Questions and answers
How well does Hyaluron-Filler Epigenetic Serum work for combination skin?
Eucerin Hyaluron-Filler Epigenetic Serum works moderately well for your combination skin, offering hydration with glycerin and hyaluronic acid without making it oily, while panthenol helps support your skin barrier. A moisturizing treatment for combination skin needs effective hydrating and skin-repairing ingredients that enhance vitality and radiance without causing irritation or excess oiliness, along with components like ceramides to boost moisture retention.
Clinical, Cosmetic and Investigational Dermatology, 2017The Journal of Dermatological Treatment, 2017
Which ingredients make this serum a good fit for combination skin?
Glycerin and hyaluronic acid make this serum a good fit for your combination skin because they provide essential hydration without making your skin oily, while panthenol helps support your skin barrier. A moisturizing treatment for combination skin needs effective hydrating ingredients that balance moisture levels and control oily shine without causing irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017The Journal of Dermatological Treatment, 2017
What does Water do for combination skin?
Water helps keep combination skin hydrated, though a product of this type needs additional barrier-protecting ingredients like ceramides or petrolatum to lock in that moisture and support overall skin health.
What does Glycerin do for combination skin?
Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017
Where does this serum go in a skincare routine for combination skin?
This serum goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening helps provide simplicity and extra safety around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this treatment with retinol by applying the serum before your retinol product. Combination skin needs a product that provides lightweight hydration with glycerin and hyaluronic acid without making oily areas heavier, while panthenol helps keep the skin barrier strong and comfortable.
Clinical, Cosmetic and Investigational Dermatology, 2017The Journal of Dermatological Treatment, 2017
How often should I use this serum?
You can use this treatment in the evening as part of your routine. Combination skin needs products with light hydrators and balancing ingredients that deliver moisture without feeling heavy or greasy.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this serum clog pores, cause breakouts or purging for combination skin?
This serum is unlikely to cause breakouts or clog pores on combination skin, as it provides hydration with glycerin and hyaluronic acid without adding heaviness. Its safety profile is excellent with no harsh ingredients, though a product for this skin also needs oil-balancing care to manage shine fully.
Can I use this serum around the eyes or on my body?
You can use this serum on the thin skin around your eyes and on your body, as its gentle ingredients are safe and well-tolerated. However, combination skin needs a moisturizing treatment with lightweight hydrators like glycerin and hyaluronic acid plus barrier-supporting panthenol to keep dry areas soft without making oily zones greasy.
Surgical and Radiologic Anatomy, 2002Clinical, Cosmetic and Investigational Dermatology, 2017
Is this serum fragrance-free and alcohol-free?
It contains fragrance (parfum) and drying alcohol (alcohol denat).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.
The Journal of Dermatological Treatment, 2017Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Ingredients
Water, Glycerin, Alcohol Denat, Hyaluronic Acid, Epicelline, Panthenol, Glyceryl Glucoside, Sodium Hydroxide, Phenoxyethanol, Parfum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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