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Drunk Elephant Protini Polypeptide Cream for combination skin

Drunk Elephant Protini Polypeptide Cream

Superior

  • HighCombination Skin Fit
  • SuperiorEffectiveness
  • HighSafety

One of the best moisturizers for combination skin.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Excellent for your combination skin, this formula leverages multiple peptides like Sh-Oligopeptide-1 and Sh-Oligopeptide-2 to promote skin regeneration and improve texture, while Lactic Acid Glycolic Acid Copolymer helps manage oiliness and reduce shine.
  • The inclusion of glycerin and sodium hyaluronate provides essential hydration without feeling heavy, supporting your skin's barrier function and collagen stimulation.
  • This product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

How to apply

  • Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
  • Apply this moisturizer after your cleanser and toner, right before your morning SPF.
  • Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
  • Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
  • Avoid the eye area when applying the moisturizer. Do a patch test before your first use.

People Say

★4.2Overall rating based on 7.5k+ reviews

Based on a very large amount of data, this moisturizer is frequently praised for its lightweight, non-greasy texture that firms and plumps the skin, making it a favorite for combination and oily skin types. It also performs well under makeup and is generally well-tolerated by sensitive skin. However, some users with very dry skin find it lacks sufficient hydration, and a significant number of reviews mention the high price point as a drawback.

Highlights

  • Lightweight texture Mostly Mentioned
    • “Gel-cream hybrid, absorbs instantly, non-greasy finish.”
  • High price Mostly Mentioned
    • “Expensive, "not worth it," "robbery" for the amount.”
  • Hygienic packaging Often Mentioned
    • “Airless pump jar, precise dosing, keeps ingredients stable.”
  • Makeup compatibility Sometimes Noted
    • “Wears well under foundation, no pilling, acts as a primer.”
  • Sensitive skin friendly Sometimes Noted
    • “Fragrance-free, non-irritating, soothing for most users.”
  • Visible results Sometimes Noted
    • “Plumper skin, improved firmness, smoother texture.”
  • Dry skin hydration Sometimes Noted
    • “Not moisturizing enough for dry skin, requires mixing with oil.”
  • Caused breakouts Rarely Noted
    • “Caused whiteheads, cystic acne, or closed comedones for some.”
  • Packaging issues Rarely Noted
    • “Hard to gauge remaining product, difficult to empty completely.”
  • Unpleasant scent Rarely Noted
    • “Smells like "play-dough," "plastic," or "yeast" (natural ingredient scent).”

Sources: lovi.care, sephora.my, influenster.com, spacenk.com, skinsort.com, ulta.com, and more

Questions and answers

What makes Drunk Elephant Protini Polypeptide Cream one of the best fits for combination skin?

This cream is an excellent fit for combination skin because it uses multiple peptides to improve texture and regeneration while copolymers help manage oiliness and reduce shine. Ingredients like glycerin and sodium hyaluronate provide essential hydration without feeling heavy, supporting your skin barrier.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for combination skin?

This cream is a great fit for combination skin because it uses multiple peptides to improve texture and regeneration, along with a copolymer to help manage oiliness and reduce shine. Ingredients like glycerin and sodium hyaluronate also provide essential hydration without feeling heavy.

Clinical, Cosmetic and Investigational Dermatology, 2017

What do Signal Peptides do for combination skin?

Signal peptides help firm combination skin and smooth out fine lines by encouraging the skin to build fresh collagen and keep its structure strong. This type of skin needs ingredients that support firmness and hydration without feeling heavy.

PloS One, 2025Journal of Cosmetic Dermatology, 2015

What does Pygmy Waterlily do for combination skin?

Pygmy Waterlily helps protect combination skin by fighting cell damage from environmental stress and supporting healthy skin cells. This plant extract is unlikely to irritate and may help keep your skin looking calm and balanced.

Pharmacology, 2016

Where does this cream go in a skincare routine for combination skin?

This cream goes in the moisturizer step of your morning and evening routine, after your hydrating toner or treatment. It provides lightweight hydration that supports your skin barrier without feeling heavy, and it is unlikely to cause irritation.

The Journal of Dermatological Treatment, 2022Clinical, Cosmetic and Investigational Dermatology, 2017

Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the retinol first and following it with this moisturizer. This combination helps keep your skin hydrated and supports its barrier while you use retinoids.

Cutis, 2006

How often should I use this cream?

This cream is designed for daily use as part of your morning and evening routine. Regular application helps maintain skin hydration and texture without feeling heavy.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to cause breakouts for combination skin, as review complaints about breakouts are low and the formula avoids harsh ingredients that typically trigger irritation. Glycerin and sodium hyaluronate provide lightweight hydration to help keep your skin balanced.

Clinical, Cosmetic and Investigational Dermatology, 2017

Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its gentle, hydrating formula works safely on thin areas like the eyelids and across various body regions. Glycerin and sodium hyaluronate provide essential moisture and support the skin barrier without feeling heavy.

Surgical and Radiologic Anatomy, 2002Clinical, Cosmetic and Investigational Dermatology, 2017

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017
  • Water lily rhizome extract protected human epidermal keratinocytes against UVB-induced mitochondria-mediated apoptosis by reducing reactive oxygen species generation, mitochondrial dysfunction, and apoptotic signaling while increasing antiapoptotic proteins and antioxidant levels.

    Pharmacology, 2016
  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011
  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022
  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019
  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020
  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001
  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

Ingredients

Water, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus Folic Acid Extract Ferment, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium Pca, Pca, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid Glycolic Acid Copolymer, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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