Bring Green Artemisia Calming Water Cream for skin with dark spots

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Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Artemisia Capillaris Thunb. extract protects human HaCaT keratinocytes from UVB-induced apoptosis and inflammation by suppressing the cGAS/STING signaling pathway.

  Journal of Photochemistry and Photobiology. B, Biology, 2024

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• Artemisia princeps-derived nanovesicles accelerate cell proliferation, decrease senescence-associated beta-galactosidase activity, inhibit MMP-1 activity more effectively than EGCG, and increase procollagen type I expression in human dermal cells and skin models.

  Journal of Extracellular Biology, 2025

• Artemisia annua aqueous extract increased the itching threshold, inhibited TSLP expression, and promoted FLG mRNA expression in in vitro and in vivo models.

  Journal of Ethnopharmacology, 2024

• Artemisia annua-loaded alginate hydrogels supplemented with hyaluronic acid and dexpanthenol accelerated in vivo wound healing by two to three days compared with untreated wounds in rats while demonstrating biocompatibility and enhancing keratinocyte migration in vitro.

  Pharmaceuticals, 2026

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Why other moisturizers fit skin with dark spots better

• Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2014

• Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.

  International Journal of Medical Sciences, 2021

Ingredients

Artemisia Capillaris Extract, Water, Glycerin, Butylene Glycol, 1,2-Hexanediol, Niacinamide, C13-16 Isoparaffin, C12-14 Isoparaffin, Bergamot Oil, Pelargonium Graveolens Oil Flower, Hydrolyzed Hibiscus Esculentus Extract, Lupinus Albus Seed Extract, Moringa Oleifera Seed Extract, Portulaca Oleracea Extract, Salvia Officinalis Oil, Pogostemon Cablin Oil, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Theobroma Cacao Seed Extract, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Artemisia Princeps Leaf Water, Brassica Oleracea Capitata Leaf Extract, Brassica Oleracea Italica Extract, Hibiscus Esculentus Fruit Extract, Spinach Leaf Extract, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Raspberry Ketone, Hydrogenated Polydecene, Pentylene Glycol, Polymethylsilsesquioxane, Vinyldimethicone, Caprylyl Methicone, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Panthenol, Dimethicone Vinyl Dimethicone Crosspolymer, Acrylate C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Glyceryl Acrylate Acrylic Acid Copolymer, Adenosine, Citric Acid, Silica, Sodium Citrate, Dextrin, Propanediol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Glycosaminoglycans, Tocopherol, Benzyl Glycol, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Ethanol, Xanthan Gum, Disodium Edta, Limonene, Citronellol, Linalool, Geraniol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.