Alastin Skincare HA Immerse Serum for dry skin
Sodium Hyaluronate
Tremella Fuciformis Sporocarp Extract Silver Ear Mushroom Extract
Hexapeptide-11
Lactoferrin
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Superior
- HighDry Skin Fit
- SuperiorEffectiveness
- ExcellentSafety
One of the best moisturizers for dry skin.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent for your dry skin, this serum deeply hydrates with high concentrations of glycerin and sodium hyaluronate, which act as humectants to attract and retain moisture, while Tremella Fuciformis Sporocarp Extract provides superior hydration for dry or flaky skin.
- The formula is also rich in peptides like Octapeptide-45 and Hexapeptide-11, which can support skin barrier function and elasticity, further benefiting dry skin.
- This product is safe for your skin, containing no harsh ingredients and featuring a blend of soothing components that minimize irritation risk.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.7Overall rating based on 400+ reviewsThis serum is widely celebrated for its transformative hydrating properties, with users reporting significant improvements in skin suppleness, radiance, and the reduction of fine lines. It is particularly favored by those with dry or mature skin for its ability to provide a "plumped" and youthful appearance without causing irritation or leaving a heavy, sticky residue.
Highlights
Instant hydration Mostly Mentioned
- “Hydrates and plumps instantly”
- “Sweet, sweet relief”
- “Quenches all the dryness”
Layers well Often Mentioned
- “Doesn't pill under makeup”
- “Layers well with other products”
- “No mask-like feeling”
Non-greasy texture Often Mentioned
- “No greasy residue”
- “Lightweight, absorbs completely”
- “Smooth and silky”
High price Often Mentioned
- “A little pricey”
- “Triple dollar sign territory”
- “Worth the investment but pricey”
Smooths fine lines Sometimes Noted
- “Less creases”
- “Lines look smoother”
- “Don't see them when I use this”
Packaging issues Rarely Noted
- “Pop-up part stops working”
- “Inner chamber came loose”
- “Rendered the spout useless”
Product longevity Rarely Noted
- “Wish it lasted longer”
- “Need to reapply during the day”
Sources: lovi.care, alastin.com, ellemesmedspa.com, lovelyskin.com, newbeauty.com, nicolesimonek.com, and more
Questions and answers
What makes Alastin HA Immerse Serum one of the best fits for dry skin?
This serum is one of the best fits for dry skin because it deeply hydrates using ingredients like glycerin and sodium hyaluronate to draw in and hold moisture. It also features silver ear mushroom extract for extra hydration, alongside peptides that help support your skin barrier and smooth feel.
Clinical, Cosmetic and Investigational Dermatology, 2017Redox Biology, 2015
Which ingredients make this serum a good fit for dry skin?
Sodium hyaluronate and glycerin make this serum a great fit for dry skin by drawing in and holding moisture, while silver ear mushroom extract and peptides help keep the skin smooth and supported. These ingredients have a safe profile and are unlikely to cause irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017Redox Biology, 2015
What does Hyaluronic Acid do for dry skin?
Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
What does Tremella Fuciformis Sporocarp Extract do for dry skin?
Tremella Fuciformis Sporocarp Extract helps dry skin by holding onto moisture and protecting the skin barrier. It works similarly to hyaluronic acid to keep your face feeling soft and smooth.
Bioscience, Biotechnology, and Biochemistry, 2014Archives of Dermatological Research, 2023
Where does this serum go in a skincare routine for dry skin?
This serum goes in the evening routine after cleansing and before your moisturizer. Using it at this time keeps things simple and helps protect your skin from sun exposure.
Can I use this serum with retinol, and in what order?
Yes, you can use this serum with retinol by applying the serum first to deeply hydrate and soothe dry skin before putting on your retinol. Using a hydrating serum like this helps support your skin barrier and makes it easier for your skin to adjust to retinol without getting too dry or irritated.
Cutis, 2006Clinical, Cosmetic and Investigational Dermatology, 2017
How often should I use this serum?
You can use this serum in the evening as part of your routine. Daily application helps keep dry skin deeply hydrated and supports your skin barrier over time.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this serum clog pores, cause breakouts or purging for dry skin?
This serum is unlikely to clog pores or cause breakouts for dry skin, as it contains no harsh ingredients and features a safe formula designed to minimize irritation. It helps keep skin smooth and comfortable without heavy oils that typically trigger blemishes.
Can I use this serum around the eyes or on my body?
This serum is safe to use around the eyes and on the body because the skin in these areas is often thinner and benefits greatly from deep moisture and soothing ingredients. Regular application helps keep dry skin smooth and comfortable while supporting overall elasticity.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Hexapeptide-11 activated proteasome, autophagy, chaperones, and antioxidant response genes, protected fibroblasts against oxidative-stress-mediated premature cellular senescence, and improved skin elasticity in human subjects.
Redox Biology, 2015The addition of Octapeptide-45 to TriHex technology (TriHex 2.0) significantly increased hyaluronic acid levels and tropoelastin intensity compared to untreated tissue, while also upregulating genes affecting the extracellular matrix and basement membrane.
Journal of Cosmetic Dermatology, 2025Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers.
Journal of Cosmetic Dermatology, 2021Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models.
Archives of Dermatological Research, 2023Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts.
In Vivo, 2022Hexapeptide-11 reversibly downregulated ATM and p53 protein expression in intrinsically aged fibroblasts, extrinsically aged fibroblasts, and extrinsically aged dermal papillae cells at concentrations between 0.1% and 1.0% in vitro, thereby influencing the onset of cellular senescence.
Journal of Cosmetic Science, 2013The combination of sodium ascorbate and lactoferrin demonstrated a significant synergistic effect on tropoelastin stimulation with intact and increased elastin fibers compared to single treatments in an ex vivo human skin model.
Journal of Cosmetic Dermatology, 2024Colostrum-derived exosome-encapsulated lactoferrin promoted cell viability and migration while reducing pro-inflammatory cytokines and phosphorylated JNK in mouse NIH/3T3 and human HS-68 fibroblasts treated with lipopolysaccharide.
Current Issues in Molecular Biology, 2025Lactoferrin treatment decreased lipid content and attenuated the mRNA expression of lipid metabolism and inflammatory genes in SZ95 human sebocytes, and reduced inflammation, lipid production, and sebaceous gland cell proliferation while increasing apoptosis in a mouse model of acne.
Journal of Cosmetic Dermatology, 2023
Ingredients
Water, Glycerin, Polyacrylate-13, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Octapeptide-45, Hexapeptide-11, Tremella Fuciformis Sporocarp Extract Silver Ear Mushroom Extract, Lactoferrin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xylitol, Propanediol, Anhydroxylitol, Xylitylglucoside, Phosphatidylserine, Glucose, Hydroxymethoxyphenyl Decanone, Tocopherol, Ascorbyl Palmitate, Dimethicone, Caprylyl Methicone, Caprylic Capric Triglyceride, Polyisobutene, Caprylyl Glycol, Disodium Edta, Betaine, Polysorbate 20, Ethylhexylglycerin, Caprylhydroxamic Acid, Sorbitan Isostearate, Helianthus Annuus Seed Oil Sunflower Seed Oil, Lecithin, Pentylene Glycol, Magnesium Chloride, Phenoxyethanol, Potassium Sorbate, Sodium Hydroxide
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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