Advanced Clinicals Collagen Skin Rescue Lotion for mature skin
Hydrolyzed Collagen
Aloe Barbadensis
Camellia Sinensis
Chamomile
GlycerinAverage
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for mature skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your normal skin due to glycerin and hydrolyzed collagen, which hydrate and support elasticity, though these ingredients are not specifically targeted for your wrinkles and fine lines.
- The inclusion of aloe barbadensis leaf juice and camellia sinensis leaf extract provides general skincare benefits and antioxidant support.
- The product is safe for your normal skin, with no risks of irritation from harsh or prohibited ingredients.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.5Overall rating based on 2.5k+ reviewsBased on a very large amount of data, this lotion is highly regarded for its ability to deeply hydrate and soften dry, crepey, or uneven skin texture. Users frequently report that it leaves skin feeling soft and firmer without a greasy residue. While it excels at providing a smooth, plump appearance through intense moisturization, some users note that its anti-aging effects are more cosmetic than transformative.
Highlights
Deeply hydrating Mostly Mentioned
- “Instantly quenches thirsty skin”
- “Keeps skin hydrated all day”
- “Relieves dry, tight skin”
Affordable price Often Mentioned
- “Great value for the size”
- “Low price, high quality”
- “Economical for daily use”
Fast absorbing Often Mentioned
- “Absorbs quickly”
- “No sticky film”
- “Melts into the skin”
Fragrance-free Sometimes Noted
- “No added scent”
- “Perfect for sensitive skin”
- “Doesn't clash with perfume”
Non-greasy feel Sometimes Noted
- “Not greasy or oily”
- “Leaves skin feeling smooth”
- “No heavy residue”
Limited anti-aging Sometimes Noted
- “Didn't see major wrinkle reduction”
- “Results are only temporary”
- “Not a miracle cure”
Insufficient moisture Rarely Noted
- “Not moisturizing enough for very dry skin”
- “Need to reapply often”
- “Felt dry after a while”
Packaging issues Rarely Noted
- “Twist-off cap is inconvenient”
- “Hard to get last bit out”
- “Pump would be better”
Potential irritation Rarely Noted
- “Caused minor breakout”
- “Skin felt itchy”
- “Not suitable for my sensitive face”
Sources: lovi.care, amazon.com, walmart.com, target.com, iherb.com, skinsort.com, and more
Questions and answers
How well does Advanced Clinicals Collagen Skin Rescue work for mature skin?
Advanced Clinicals Collagen Skin Rescue Lotion is an average fit for mature skin, providing moderate moisture and soothing benefits with glycerin and aloe, though it lacks targeted ingredients for lines and wrinkles. To truly care for mature skin, a product of this type needs rich softening and hydrating ingredients alongside powerful anti-aging components like peptides and antioxidants.
Which ingredients make this cream a good fit for mature skin?
Glycerin and hydrolyzed collagen help hydrate and support elasticity, while aloe barbadensis and camellia sinensis provide antioxidant support. To better fit mature skin, a product of this type needs potent anti-aging ingredients that specifically target wrinkles and fine lines, along with a rich blend of softening and deeply hydrating components.
Clinical, Cosmetic and Investigational Dermatology, 2017Carcinogenesis, 2001
What does Hydrolyzed Collagen do for mature skin?
Hydrolyzed collagen helps reduce wrinkles and improves skin elasticity and moisture in mature skin. Regular intake supports skin density and smoothness while helping to prevent the breakdown of natural collagen.
What does Aloe Vera do for mature skin?
Aloe vera helps smooth out fine lines and wrinkles by supporting collagen production, keeping mature skin feeling soft and elastic. It is unlikely to cause irritation and may improve skin firmness over time.
Where does it go in a skincare routine for mature skin?
This moisturizing treatment goes in your evening routine after cleansing and before your moisturizer. Mature skin needs targeted ingredients like retinoids, peptides, or antioxidants that specifically smooth fine lines and boost elasticity.
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying the retinol first and following it with this moisturizer to help keep your skin soft and calm while reducing irritation. Applying a barrier-improving moisturizer alongside topical retinoids is well-supported for making your routine more comfortable.
How often should I use it?
You can use this moisturizing treatment daily to keep your skin soft and hydrated. Twice-daily application helps maintain moisture and smooth dryness in aging skin.
Health Science Reports, 2021Journal of Drugs in Dermatology, 2015
Can this cream clog pores, cause breakouts or purging for mature skin?
This lotion is unlikely to clog pores or cause breakouts for mature skin, as it has a safe profile without harsh ingredients that irritate. However, because it only offers moderate moisture, mature skin needing better care for wrinkles and fine lines requires richer formulas with targeted anti-aging ingredients and deep hydrators to keep skin smooth and firm.
Can I use it around the eyes or on my body?
You can use this moisturizing treatment on your body, but you should avoid applying it to the thin skin around your eyes. A product of this type needs specialized firming and smoothing ingredients, along with a high safety profile, to properly care for delicate eye areas and mature skin.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical application of (-)-epigallocatechin-3-gallate (EGCG) to human skin before UV irradiation decreases UV-induced production of hydrogen peroxide by 68-90% and nitric oxide by 30-100%, inhibits leukocyte infiltration and lipid peroxidation by 41-84%, and restores glutathione levels and glutathione peroxidase activity compared to UV exposure alone.
Carcinogenesis, 2001Topical epigallocatechin-3-gallate application and zonal priming reduced scar thickness and VEGFA, decreased mast cells, increased M2 macrophages and hydration, and improved elasticity compared with placebo in human scars.
The Journal of Investigative Dermatology, 2019Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.
Experimental Dermatology, 2009Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.
Plastic and Reconstructive Surgery, 2018Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.
Journal of Alternative and Complementary Medicine, 2010Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.
Journal of Clinical and Diagnostic Research, 2017An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.
Clinical, Cosmetic and Investigational Dermatology, 2019Topical application of green tea extract encapsulated chitosan microparticles improved skin elasticity, melanin index, and facial wrinkles compared to a placebo in female volunteers without causing skin irritation.
Journal of Cosmetic Dermatology, 2022Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream.
International Journal of Molecular Medicine, 2016Topical chamomile oil combined with a night splint significantly improved the symptomatic and functional status of patients with severe carpal tunnel syndrome compared to placebo, while electrodiagnostic parameters showed no significant changes.
Complementary Therapies in Clinical Practice, 2015German chamomile solution applied twice a day healed peristomal skin lesions significantly faster than once-a-day 1% hydrocortisone ointment in colostomy patients, with a mean healing time of 8.89 days versus 14.53 days.
Ostomy/wound Management, 2011The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012
Why other moisturizers fit mature skin better
Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers.
International Journal of Medical Sciences, 2021Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement.
Nanomaterials, 2024Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026
Ingredients
Water, Mineral Oil, Cetearyl Alcohol, Glyceryl Stearate Se, Isopropyl Myristate, Glycerin, Butylene Glycol, Ceteareth-20, Caprylic Capric Triglyceride, Hydrolyzed Collagen, Aloe Barbadensis Leaf Juice, Camellia Sinensis Leaf Extract, Anthemis Nobilis Flower Extract, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Maltodextrin, Phenoxyethanol, Iodopropynyl Butylcarbamate, Caprylyl Glycol, Sodium Hydroxide
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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