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Citric acid and hexapeptide-9

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Citric acid and hexapeptide-9: keep them apart

Keep them apart

Use them at different times of day with citric acid in the morning and hexapeptide-9 at night because acid ruins peptide results. Citric acid makes your skin too acidic, which breaks down the hexapeptide-9 and stops it from firming your skin. You can easily fix this by applying them in separate routines, like using the acid in the morning and the peptide at night.

Citric acid products

Hexapeptide-9 products

Questions and answers

Can you use citric acid and hexapeptide-9 together?

No, you should keep citric acid and hexapeptide-9 apart in your routine because the acidic environment may destabilize the peptide bonds and reduce their effectiveness. Use them in separate steps or routines, such as applying acids and peptides at different times of the day.

Which goes first, citric acid or hexapeptide-9?

Keep citric acid and hexapeptide-9 apart because the acidic environment may destabilize the peptide bonds and reduce bioactivity. Use them in separate routines or steps, such as applying acids and peptides at different times of day.

Are citric acid and hexapeptide-9 good for sensitive skin?

Citric acid and hexapeptide-9 should be kept apart in your routine because the low pH of acids may destabilize peptides and reduce their activity, which is especially important to avoid for sensitive skin. You can use them in separate steps or routines, such as applying an acid in the morning and a peptide at night.

Research on citric acid and hexapeptide-9

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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