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Olay vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Olay and Sesderma are distinguished skincare lines known for distinct formulations tailored to varied needs. Olay offers targeted moisturizers, eye products, serums, cleansers, and more that thoughtfully pair niacinamide and glycerin to suit acne-prone and mature skin best, while the Spanish brand Sesderma is beloved for advanced serums and meticulously engineered formulas with botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types best. These brands differ primarily in their core ingredient approaches and specific product offerings, with the former featuring standouts like the Super Eyes Daily Eye Serum, Regenerist Luminous Tone Perfecting Cream, and Brightening Eye Cream, and the latter highlighting the Azelac RU Serum to refine skin texture and promote a radiant complexion.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Olay and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Olay vs Sesderma products

Questions and answers

Olay or Sesderma: which is better?

Olay offers a much wider variety of products on this page compared to Sesderma, with strong options suited for acne-prone, mature, and sensitive skin types.

What is the difference between Olay and Sesderma?

Olay features a wide variety of skincare products on this page with a strong focus on acne-prone, mature, and sensitive skin types, whereas Sesderma offers only a single serum. Additionally, nearly all Olay products on this page are fragrance-free, while the Sesderma product includes fragrance.

Which is more affordable, Olay or Sesderma?

This public Lovi page does not compare the prices or affordability of Olay and Sesderma products.

Which causes fewer breakouts, Olay or Sesderma?

Olay features multiple products on this page rated with a High Lovi fit for acne-prone skin, such as the Super Serum and Regenerist Ultra Rich Hydrating Moisturizer, whereas Sesderma includes only a single product on the page with an Average Lovi fit for acne-prone skin.

How does the founding year and country of origin compare between Olay and Sesderma?

Olay was founded in 1952 with an unspecified country of origin, whereas Sesderma was founded in 1989 in Spain.

Which brand offers more fragrance-free options among their products, Olay or Sesderma?

Olay offers significantly more fragrance-free options, as 26 of the 27 products on this page list no fragrance, whereas Sesderma includes fragrance in its single product.

What specific Lovi fit level does Sesderma's Azelac RU Serum have for dry skin compared to Olay's serums?

Sesderma's Azelac RU Serum has a Low Lovi fit level for dry skin, whereas Olay's serums such as Super Serum, Super Serum Night Repair, and Regenerist Regenerating Serum all have a High Lovi fit level for dry skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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