DHC vs Minimalist

Questions and answers

Research behind their key ingredients

• Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin

  Retinol · The Journal of Investigative Dermatology, 2000

• Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

  Sodium hyaluronate · Dermatologic Therapy, 2022

• Topical use of dexpanthenol in skin disorders

  Panthenol · American Journal of Clinical Dermatology, 2002

• Improvement of naturally aged skin with vitamin A (retinol)

  Retinol · Archives of Dermatology, 2007

• Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial

  Tocopherol · Journal of Cosmetic Dermatology, 2020

• Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo

  Retinol · International Journal of Cosmetic Science, 2017

• Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing

  Retinol · The British Journal of Dermatology, 2019

• Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter

  Titanium dioxide · International Journal of Cosmetic Science, 2000

• Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin

  Xylitol · Acta Dermato-venereologica, 2017

• The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study

  Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017

• The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide

  Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001

• A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora

  Panthenol · The Journal of Dermatological Treatment, 2017

• A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population

  Salicylic acid · BioMed Research International, 2020

• Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial

  Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach

  Zinc · Journal of Controlled Release, 2025

• Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study

  Salicylic acid · Journal of Cosmetic Dermatology, 2024

• Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial

  Copper · Journal of Cosmetic Dermatology, 2019

• A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide

  Salicylic acid · Journal of Drugs in Dermatology, 2023

• Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial

  Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020

• Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study

  Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023

• Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris

  Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2021

• Formulation strategies to modulate the topical delivery of anti-inflammatory compounds

  Stearyl glycyrrhetinate · Journal of Cosmetic Science, 2013

• Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders

  3-o-ethyl ascorbic acid · Polymers, 2023

• Comparison of methods for assessing photoprotection against ultraviolet A in vivo

  Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987

• Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters

  Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019

• Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters

  Octocrylene · Antioxidants, 2025

• Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study

  Panthenol · Journal of Cosmetic Dermatology, 2025

• TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection

  Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023

• Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays

  Xylitol · Molecules, 2021

• Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum

  Caprylic capric triglyceride · Life, 2023

• Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris

  Capryloyl salicylic acid · Journal of Drugs in Dermatology, 2013

• Facial disbiosis and UV filters

  Octocrylene · Archives of Dermatological Research, 2024

• Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial

  Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021

• Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study

  Zinc gluconate · Journal of Cosmetic Dermatology, 2026

• Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial

  Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.