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Glycolic acid and acetyl hexapeptide-3

Glycolic acid and acetyl hexapeptide-3: keep them apart

Keep them apart

Use them at different times of day with glycolic acid in the morning and acetyl hexapeptide-3 at night because acid ruins peptide strength. Glycolic acid is too acidic and breaks down the peptide, making it stop working. You can use a gentler acid or wait longer between applying them.

Questions and answers

Can you use glycolic acid and acetyl hexapeptide-3 together?

Keep glycolic acid and acetyl hexapeptide-3 apart because the low pH of glycolic acid destabilizes the peptide and reduces its bioactivity. Use them in separate steps or routines, such as AM and PM separation.

Which goes first, glycolic acid or acetyl hexapeptide-3?

Keep glycolic acid and acetyl hexapeptide-3 apart by using them in separate routines, such as AM and PM, because the low pH of glycolic acid may destabilize the peptide.

Are glycolic acid and acetyl hexapeptide-3 good for sensitive skin?

No, you should keep glycolic acid and acetyl hexapeptide-3 apart because the acidic environment destabilizes peptide bonds and reduces bioactivity. Sensitive skin should avoid low-pH overlap by using these ingredients in separate routines.

Research on glycolic acid and acetyl hexapeptide-3

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

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