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Niacinamide and acetyl hexapeptide-3

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Niacinamide and acetyl hexapeptide-3: depends on the strength

Depends on the strength

Use them together in the same routine, because niacinamide helps strengthen your skin while peptides work on firmness. Niacinamide boosts your skin barrier and pairs wonderfully with peptides to improve overall anti-aging results. You can keep using them both together without making any changes.

Niacinamide products

Acetyl hexapeptide-3 products

Questions and answers

Can you use niacinamide and acetyl hexapeptide-3 together?

Yes, you can use niacinamide and acetyl hexapeptide-3 together depending on the strength, and they are found together in products like Rhode Peptide Glazing Fluid and La Mer The Regenerating Serum. This combination helps strengthen the skin barrier and complement peptide regeneration. Clinical trials show that using these ingredients together helps reduce the progression of skin aging.

Antioxidants, 2021American Journal of Clinical Dermatology, 2013

Which goes first, niacinamide or acetyl hexapeptide-3?

Whether niacinamide or acetyl hexapeptide-3 goes first depends on the product strength you are using. You can find both ingredients together in finished products like Rhode Peptide Glazing Fluid and Heimish Marine Care Eye Cream.

Are niacinamide and acetyl hexapeptide-3 good for sensitive skin?

Niacinamide and acetyl hexapeptide-3 depend on the product strength for sensitive skin, and they are ideal together in anti-aging and barrier repair products to strengthen the skin barrier. Products like Heimish Marine Care Eye Cream and Rhode Peptide Glazing Fluid contain both ingredients.

Research on niacinamide and acetyl hexapeptide-3

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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