Cetaphil vs ISDIN
Cetaphil and ISDIN are established skincare brands offering distinct approaches to daily care, with the former founded in 1947 by Galderma Group AG and the latter originating in Spain in 1975 under Puig. The American brand provides thoughtful cleansers, moisturizers, serums, and sunscreens featuring glycerin, niacinamide, and panthenol to suit combination skin and acne-prone skin best. Meanwhile, the Spanish brand is beloved for sophisticated moisturizers, advanced sunscreens, targeted serums, and soothing eye products that suit dry skin and combination skin best. While both cater to overlapping skin types, they differ in their specific formulations and targeted standalone solutions for concerns like dark spots and mature skin.
Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.
en.wikipedia.orgcetaphil.co.uk
ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.
puig.combeautymatter.comuploads.puig.com
This page compares some of the most popular Cetaphil and ISDIN products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Cetaphil vs ISDIN products
People Say
Gentle for sensitive skin Mostly MentionedOften Mentioned
- “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser”
- “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser”
- “cleans without stripping — Cetaphil Daily Facial Cleanser”
- “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
Lightweight and non-greasy Often MentionedMostly Mentioned
- “absorbs instantly — ISDIN Eryfotona Actinica”
- “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water”
- “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate”
- “absorbs instantly — Cetaphil Moisturizing Lotion”
Hydrating and non-stripping Mostly MentionedMostly Mentioned
- “cleared up flaky skin — Cetaphil Moisturizing Cream”
- “healed my dry patches — Cetaphil Moisturising Cream”
- “Improved moisture and texture — ISDIN Hyaluronic Moisture”
- “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water”
Skin smoothing and texture improvements Sometimes NotedRarely Noted
- “Skin felt softer after one use — Cetaphil Gentle Exfoliating SA Cleanser”
- “Micro-fine granules don't irritate — Cetaphil Extra Gentle Daily Scrub”
- “skin was much smoother — ISDIN Retinal Intense Serum”
Versatile use and daily cleansing Often MentionedNot noted
- “great for face and body — Cetaphil Moisturizing Cream”
- “recommended by my derm — Cetaphil Daily Facial Cleanser”
- “removes excess oil — Cetaphil Daily Facial Cleanser”
Brightening and complexion benefits Rarely NotedSometimes Noted
- “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- “skin looks immediately luminous — ISDIN K-Ox Eyes”
- “skin looks more radiant — Cetaphil Vitamin C Serum”
Packaging and price complaints Rarely NotedMostly Mentioned
- “hate dipping fingers in — Cetaphil Moisturising Cream”
- “wish it had a pump — Cetaphil Moisturizing Cream”
- “expensive for drugstore — Cetaphil Moisturizing Cream”
- “very expensive — ISDIN Eryfotona Actinica”
Strong scent or fragrance concerns Sometimes NotedOften Mentioned
- “Overpowering masking fragrance — Cetaphil Gentle Cleansing Bar”
- “Scent is overwhelmingly artificial. — Cetaphil Oily Skin Cleanser”
- “smell is overpowering — ISDIN Eryfotona Actinica”
Formula changes and irritation Sometimes NotedRarely Noted
- “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum”
- “slight peeling — ISDIN Retinal Intense Serum”
- “New version burns my face. — Cetaphil Gentle Skin Cleanser”
Cetaphil vs ISDIN routines for dry skin
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Cleanser
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Morning · Evening · Once a week
€19.75
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€12.59
-
Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
€16.99
-
SPF
Fusion Water
Morning
€25.99
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€19.00
-
Cleanser
Gentle Skin Cleanser
Morning · Evening · Once a week
€15.19
-
Hydrating Toner
Dear, Klairs Supple Preparation Unscented Toner
Morning
€12.59
-
Moisturizer
Rich Hydrating Night Cream
Morning · Evening · Once a week
€22.42
-
SPF
Sheer Mineral Sunscreen SPF 50
Morning
€30.12
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Nourishing Mask
MEDIHEAL Vita Essential Mask
Once a week
€19.00
Cetaphil vs ISDIN routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
€11.75
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€16.59
-
Moisturizer
CeraVe PM Facial Moisturizing Lotion
Morning · Evening · Once a week
€38.99
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
€81.80
-
Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€24.59
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€16.59
-
Moisturizer
Ceramide Serum
Morning · Evening · Once a week
€39.77
-
SPF
Oil Control
Morning
€23.48
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Dr. Sebagh Deep Exfoliating Mask
Once a week
€81.80
Cetaphil vs ISDIN routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
€39.99
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Some By Mi Yuja Niacin Brightening Moisture Gel Cream
Morning · Evening · Once a week
€13.67
-
SPF
Eryfotona Actinica
Morning
€32.49
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Flavo-C Serum
Evening · Once a week
€44.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
-
Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€24.59
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Ceramide Serum
Morning · Evening · Once a week
€39.77
-
SPF
Sheer Mineral Sunscreen SPF 50
Morning
€30.12
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€104.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
Questions and answers
Cetaphil or ISDIN: which is better?
ISDIN is generally superior, providing a Superior Lovi routine fit for dry, sensitive, mature, and dark-spot skin, whereas Cetaphil offers a High fit for those types. Both brands achieve equal Superior routine fits for combination, acne-prone, and oily skin types.
What is the difference between Cetaphil and ISDIN?
Cetaphil is a US-founded brand owned by Galderma that tends to be gentler for sensitive skin, while ISDIN is a Spanish brand owned by Puig that is known for lightweight sunscreens and brightening benefits. Both brands offer products that fit combination and acne-prone skin well, but ISDIN achieves a Superior routine fit for dry and sensitive skin compared to Cetaphil's High fit.
Cetaphil or ISDIN for dry skin?
Both brands are a strong choice for dry skin, with Lovi giving ISDIN a Superior routine fit and Cetaphil a High fit. The products on this page from both brands feature hydrating ingredients like hyaluronic acid, which helps improve skin quality.
Cetaphil or ISDIN: which moisturizer is better?
Both brands offer moisturizers on this page, with ISDIN achieving a Superior routine fit for dry skin while Cetaphil reaches a High level. ISDIN is mostly noted for lightweight moisturizers, whereas Cetaphil reviewers often mention hydrating and non-greasy formulas.
Which is more affordable, Cetaphil or ISDIN?
Reviewers on this page frequently complain about the high price point of ISDIN products, while price complaints for Cetaphil center around packaging and price.
Which brand has more fragrance-free products, Cetaphil or ISDIN?
Cetaphil has more fragrance-free products on this page, with twenty-six out of twenty-seven items listing no fragrance. ISDIN lists no fragrance for only three of its eight products on the page.
Cetaphil or ISDIN for oily skin?
Both brands are great choices for oily skin, with Lovi rating Cetaphil High and ISDIN Superior for this skin type. ISDIN is widely praised for its ultralight sunscreens, while Cetaphil is known for gentle, non-stripping cleansers.
Cetaphil or ISDIN: which sunscreen is better?
Both brands offer strong sunscreen options, but ISDIN stands out with Superior routine fit levels for sunscreens like Eryfotona Actinica and Fusion Water that reviewers praise as ultralight and makeup-friendly. Cetaphil also provides reliable daily sun protection, such as its Sheer Mineral Sunscreen SPF 50, which is well-suited for sensitive skin.
Cetaphil or ISDIN for sensitive skin?
Both Cetaphil and ISDIN are suitable choices, but ISDIN is rated as a Superior fit for sensitive skin while Cetaphil is rated as a High fit. Cetaphil features gentle, non-stripping cleansers with almost no fragrance across the products on this page, whereas ISDIN offers ultralight sunscreens and lightweight moisturizers.
Cetaphil or ISDIN: which serum is better?
Both brands offer effective serums, with Cetaphil providing options like its Healthy Radiance Antioxidant-C Serum and ISDIN offering treatments such as its Flavo-C Serum. Lovi rates both brands as having high or superior fit levels for various skin types when using their respective serums. Topical ascorbic acid and vitamin C help improve photoaged skin and provide antioxidant effects.
Journal of Cosmetic Dermatology, 2020Experimental Dermatology, 2003
Cetaphil or ISDIN for acne-prone skin?
Both brands are a strong match for acne-prone skin, with Lovi rating Cetaphil Superior and ISDIN Superior. Cetaphil products on this page often help soothe blemishes while keeping formulas mostly fragrance-free.
Cetaphil or ISDIN for mature skin?
ISDIN is a Superior fit for mature skin, whereas Cetaphil has a High fit level for this skin type. ISDIN helps deliver antioxidant and anti-aging benefits using ingredients like hyaluronic acid and vitamin C.
Research behind their key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Comparison of methods for assessing photoprotection against ultraviolet A in vivo
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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