Sesderma vs OPTASE
Sesderma and OPTASE are respected skincare lines designed to address diverse dermatological needs. Sesderma is known for its advanced serums and meticulously engineered formulas utilizing botanical extracts and active compounds, suiting sensitive, hyperpigmented, and aging skin types best with standout products like the Azelac RU Serum for acne-prone skin. Meanwhile, the brand is beloved for gentle makeup removers and carefully balanced formulas that suit sensitive, dry, and irritated skin best, offering soothing and restorative qualities through reliable options such as the LIFE SENSITIVE EYE MAKEUP REMOVER for acne-prone skin. While both support calm daily routines, they differ as the former refines skin texture and promotes radiance, whereas the latter consistently supports comfortable care.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Sesderma and OPTASE products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Sesderma or OPTASE: which is better?
Neither brand is universally better, as Sesderma earns a High Lovi fit for acne-prone skin and dark spots with its Azelac RU Serum, while OPTASE earns a High Lovi fit for sensitive skin with its LIFE SENSITIVE EYE MAKEUP REMOVER. Shoppers should note that the Azelac RU Serum contains fragrance, whereas the products on this page from OPTASE are fragrance-free.
What is the difference between Sesderma and OPTASE?
Sesderma offers the Azelac RU Serum, which has a High Lovi fit for acne-prone skin, combination skin, and skin with dark spots, though it contains fragrance. OPTASE offers the LIFE SENSITIVE EYE MAKEUP REMOVER, which achieves a High Lovi fit for sensitive skin and contains no fragrance across the products on this page.
Which is more affordable, Sesderma or OPTASE?
The products on this page for both Sesderma and OPTASE do not list pricing details, so neither brand can be called more affordable than the other.
Which causes fewer breakouts, Sesderma or OPTASE?
For acne-prone skin, Sesderma has a High Lovi fit with its Azelac RU Serum, while OPTASE has an Average fit with its LIFE SENSITIVE EYE MAKEUP REMOVER. Azelaic acid helps reduce acne-prone skin symptoms.
Which brand was founded earlier, Sesderma or OPTASE?
Sesderma was founded earlier than OPTASE, having started in Spain in 1989 while OPTASE was founded in 2016.
Do both Sesderma and OPTASE products contain fragrance?
Sesderma includes fragrance in its products on this page, whereas OPTASE features no fragrance across its items.
Which brand offers a serum for skin with dark spots?
Sesderma offers a serum for skin with dark spots through its Azelac RU Serum, which Lovi rates as a High fit for skin with dark spots. OPTASE does not offer a serum on this page.
Research behind their key ingredients
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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