SOME BY MI Yuja Niacin Mineral 100 Brightening Sun Cream for combination skin

How to apply

Questions and answers

What the research says

• Microfine titanium dioxide does not penetrate human skin when formulated in an oil-in-water emulsion with the pigment dispersed in the aqueous phase, compared to oily dispersions and liposomal encapsulation which allow deeper skin penetration.

  International Journal of Cosmetic Science, 2000

• Topical application of micronised titanium dioxide results in no dermal absorption, with the particles being deposited solely on the outermost surface of the stratum corneum.

  Skin Pharmacology and Applied Skin Physiology, 2001

• Replacing microsized titanium dioxide and zinc oxide with nanoparticles in sunscreens eliminates opaqueness and alters UV protection balance while inducing (photo)cyto- and genotoxicity and penetrating viable skin layers during long-term exposures.

  Nanotechnology, Science and Applications, 2011

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Citrus junos callus extract decreased melanin content in melanocytes 1.85-fold compared with arbutin and promoted the proliferation of and procollagen synthesis by human fibroblasts by 154% and 176% at 500 μg/mL.

  Molecules, 2017

• Yuja-peel fractions (ethyl acetate, hexane, and butanol) inhibited MMP expression, induced moisturizing factors filaggrin and serine palmitoyltransferase, and decreased melanin content in UVB-irradiated HaCaT, HDF, and α-MSH-treated B16F10 cells.

  Antioxidants, 2022

• Upcycled low-molecular-weight anionic peptides from Citrus junos seeds protected UVR-irradiated keratinocytes and reconstructed skin tissue by scavenging reactive oxygen species, reducing paracrine cytokines, inhibiting melanin synthesis and TRP-2 expression, and increasing filaggrin, laminin-5, and type I collagen expression.

  International Journal of Molecular Sciences, 2024

• Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema.

  Biomedicines, 2025

• Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness.

  Clinical and Experimental Dermatology, 2000

• Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin.

  Nanomedicine, 2016

• Microfine zinc oxide and titanium dioxide do not penetrate the stratum corneum of porcine skin in vitro, indicating that their use in sunscreens does not pose a health risk from internal exposure.

  Toxicology in Vitro, 2006

• Hyaluronic acid-grafted titanium dioxide nanoparticles increased SPF from 13.3 to 19.1 while demonstrating low photocatalytic activity, exceptional thermal stability with >95% SPF retention, enhanced moisturization with >80% hydration retention, and minimal cytotoxicity with 88.5% cell viability in HaCaT keratinocytes compared to unmodified nanoparticles.

  International Journal of Biological Macromolecules, 2025

• UVB-damaged skin slightly enhanced titanium dioxide and zinc oxide nanoparticle penetration from sunscreen formulations, but minimal transdermal absorption was detected in pigs.

  Toxicological Sciences, 2011

• A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability.

  Journal of Cosmetic Science, 2020

• Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations.

  Heliyon, 2023

• Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants.

  Journal of Cosmetic Dermatology, 2025

Ingredients

Water, Cyclohexasiloxane, Zinc Oxide, Titanium Dioxide Ci 77891, Propanediol, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Dibutyl Adipate, Niacinamide, Caprylyl Methicone, 1,2-Hexanediol, Disteardimonium Hectorite, Betaine, Magnesium Sulfate, Panthenol, Hydrogen Dimethicone, Inositol, Aluminum Hydroxide, C30-45 Alkyl Cetearyl Dimethicone Crosspolymer, Polyglyceryl-2 Dipolyhydroxystearate, Styrene Acrylates Copolymer, Stearic Acid, Bergamot Oil Fruit, Pentylene Glycol, Ethylhexylglycerin, Octyldodecanol, Adenosine, Triethoxycaprylylsilane, Salvia Officinalis Oil, Glutathione, Arbutin, Bisabolol, Echium Plantagineum Seed Oil, Glycerin, Butylene Glycol, Nelumbo Nucifera Flower Extract, Cardiospermum Halicacabum Vine Extract Flower Leaf, Helianthus Annuus Seed Oil Sunflower Seed Oil, Hydrogenated Lecithin, Polyglyceryl-10 Stearate, Dicaprylyl Carbonate, Cetearyl Isononanoate, Sodium Ascorbyl Phosphate, Tocopherol, Citrus Junos Fruit Extract, Folic Acid, Biotin, Pyridoxine, Cyanocobalamin, Linoleic Acid, Thiamine Hcl, Beta-Carotene, Riboflavin, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.