COSRX The 6 Peptide Skin Booster Serum for acne-prone skin
Sodium Hyaluronate
Peptides
N-Acetyl Glucosamine
Niacinamide
AllantoinHigh
- HighCombination Skin Fit
- SuperiorEffectiveness
- ExcellentSafety
A great choice for acne-prone skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent for your combination skin and acne concerns, as niacinamide helps regulate oil production and reduce inflammation, while acetyl hexapeptide-8 supports skin health and combats breakouts. Polyquaternium-51 provides essential hydration, balancing both oily and dry areas effectively.
- The high concentrations of peptides like copper tripeptide-1 and acetyl hexapeptide-8 offer significant moisturizing and anti-aging benefits, visibly reducing fine lines and wrinkles.
- The formula is safe for your skin, containing soothing ingredients like tocopherol and allantoin and lacking any harsh or irritating components.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.7Overall rating based on 5.4k+ reviewsBased on a very large amount of data, users consistently praise this serum as a lightweight, water-like "booster" that significantly improves skin texture and hydration without heaviness. It is widely celebrated for smoothing pores and creating a "glass skin" glow. A small minority of users with specific sensitivities experienced breakouts or closed comedones.
Highlights
Lightweight & fast-absorbing Mostly Mentioned
- “absorbs instantly like water”
- “non-sticky finish”
- “perfect for layering”
- “feels weightless on oily skin”
Hydrating & plumping Often Mentioned
- “gives a healthy glow”
- “skin feels plump”
- “boosts hydration levels”
- “glass skin effect”
Improves skin texture Often Mentioned
- “skin feels softer immediately”
- “smoothed out my texture”
- “pores look smaller”
- “reduced roughness”
Gentle & non-irritating Sometimes Noted
- “no stinging on sensitive skin”
- “soothing application”
- “great for barrier repair”
- “gentle enough for daily use”
Caused breakouts Rarely Noted
- “gave me closed comedones”
- “caused tiny whiteheads”
- “broke me out after a week”
- “bad reaction for acne-prone skin”
Ingredient sensitivities Rarely Noted
- “reacted to the niacinamide”
- “contains soy oil (allergy warning)”
- “caused redness/flushing”
No visible results Rarely Noted
- “did absolutely nothing”
- “just expensive water”
- “no change in fine lines”
- “saw no difference after a bottle”
Sticky residue Rarely Noted
- “felt slightly tacky”
- “left a sticky film”
- “clashed with other products”
- “too slimy”
Sources: lovi.care, ulta.com, sokoglam.com, yesstyle.com, oliveyoung.com, amazon.com, and more
Questions and answers
What makes COSRX The 6 Peptide Skin Booster Serum a great fit for acne-prone skin?
COSRX The 6 Peptide Skin Booster Serum is a great fit for acne-prone skin because niacinamide helps regulate oil production and reduce inflammation, while peptides like acetyl hexapeptide-8 support skin health and combat breakouts. The formula also provides essential hydration to balance oily and dry areas effectively without any harsh components.
American Journal of Clinical Dermatology, 2013Annals of Dermatology, 2019
Which ingredients make this serum a good fit for acne-prone skin?
Niacinamide helps regulate oil production and reduce inflammation, while acetyl hexapeptide-8 supports skin health and combats breakouts. Additionally, soothing components like allantoin and tocopherol help keep acne-prone skin calm and comfortable.
What does Hyaluronic Acid do for acne-prone skin?
Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
What do Peptides do for acne-prone skin?
Peptides help calm acne-prone skin by reducing redness and soothing inflammation while supporting the skin barrier. Certain advanced peptide formulas also work to target acne-causing bacteria and help balance oil production.
Biochemical Pharmacology, 2025Bioresources and Bioprocessing, 2026
Where does this serum go in a skincare routine for acne-prone skin?
This serum goes in the evening routine as a treatment step, applied after cleansing and before moisturizing. Putting treatments in the evening helps keep things simple and provides extra safety around sun exposure.
Can I use it with retinol, and in what order?
Yes, you can use this moisturizing treatment with retinol by applying the treatment first to keep your skin calm and hydrated, followed by your retinol. This layered approach helps reduce the irritation and dryness that retinol can sometimes cause on acne-prone skin.
How often should I use this serum?
You can use this serum daily as part of your evening routine. Daily application helps keep acne-prone skin balanced and hydrated while improving overall texture and reducing breakouts.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can it clog pores, cause breakouts or purging for acne-prone skin?
This serum is a great fit for acne-prone skin because niacinamide helps balance oil and soothe redness, while soothing ingredients like allantoin keep the formula gentle and unlikely to cause irritation. Reviewers rarely mention breakouts, and the gentle ingredients mean it is unlikely to clog pores.
Can I use this serum around the eyes or on my body?
You can safely use this moisturizing treatment on the thin skin around your eyes and on your body to help smooth fine lines and keep areas soft and hydrated. It is unlikely to cause irritation because the formula includes soothing ingredients and lacks harsh components.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide.
Journal of Cosmetic Dermatology, 2007N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers.
Advanced Pharmaceutical Bulletin, 2016Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants.
Journal of Cosmetic and Laser Therapy, 2019Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018
Ingredients
Water, Dipropylene Glycol, Glycerin, Pentylene Glycol, 1,2-Hexanediol, Niacinamide, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyacrylate Crosspolymer-6, Butylene Glycol, Xanthan Gum, Ethylhexylglycerin, Adenosine, Polyquaternium-51, Disodium Edta, Citric Acid, Caprylyl Glycol, Betaine, T-Butyl Alcohol, Sodium Pca, Sodium Lactate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Pca, Sh-Polypeptide-121, Serine, Alanine, Allantoin, Sodium Hyaluronate, Acetyl Glucosamine, Glycine, Glutamic Acid, Lysine Hcl, Threonine, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Arginine, Tocopherol, Oligopeptide-68, Proline, Dextran, Palmitoyl Tripeptide-8, Glycine Soja Oil Soybean Oil, Hydrogenated Lecithin, Potassium Sorbate, Sodium Oleate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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