Clinique Dramatically Different Moisturizing Lotion+ for dry sensitive skin
Glycerin
Sodium Hyaluronate
Sesamum Indicum Oil
Cucumis Sativus Fruit Extract
Hordeum Vulgare Extract
Average
- HighDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry sensitive skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate hydration for your dry and sensitive skin, as glycerin and sodium hyaluronate provide humectant benefits while petrolatum and mineral oil offer emollient and occlusive actions. Urea further supports dry or flaky skin by aiding in moisture retention.
- The formula is generally safe for your dry and sensitive skin, with soothing ingredients like glycerin and urea present and no harsh or prohibited components identified.
- While providing good basic hydration, the formulation does not offer targeted solutions for specific skin concerns beyond general dryness.
How to apply
- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
People Say
★4.5Overall rating based on 15.0k+ reviewsBased on a very large amount of data, this lotion is a highly regarded staple for dry and combination skin, frequently praised for restoring the moisture barrier and leaving a soft, non-greasy finish. Most users report improved hydration and a healthy glow. A moderate number of users experienced breakouts or found the texture too heavy for oily areas.
Highlights
Effective hydration Mostly Mentioned
- “Keeps my dry patches at bay all day”
- “Skin feels instantly plump and quenched”
- “Restored my moisture barrier after over-exfoliating”
- “Provides all-day comfort without tightness”
Lightweight texture Often Mentioned
- “Absorbs quickly without feeling sticky”
- “Silky consistency that spreads easily”
- “Doesn't feel heavy or mask-like”
- “Sinks in within seconds”
Gentle/fragrance-free Sometimes Noted
- “Great for my sensitive, reactive skin”
- “No strong scents to irritate my nose”
- “Soothing on redness and irritation”
- “Doesn't sting even when my skin is raw”
Makeup compatibility Sometimes Noted
- “Foundation glides on perfectly over it”
- “Doesn't pill under sunscreen or makeup”
- “Creates a smooth, hydrated canvas”
- “My makeup looks less cakey”
Caused breakouts Sometimes Noted
- “Woke up with whiteheads on my chin”
- “Caused deep cystic acne after a week”
- “Too rich, clogged my pores”
- “My skin cleared up once I stopped using it”
Formula change Rarely Noted
- “New formula isn't as good as the original”
- “Caused a reaction unlike the old version”
- “Miss the yellow bottle from 10 years ago”
- “Feels different than I remember”
Greasy residue Rarely Noted
- “Left an oily film on my T-zone”
- “Looked like a greaseball by noon”
- “Sits on top of skin rather than absorbing”
- “Too shiny for daytime use”
Unpleasant scent Rarely Noted
- “Has a weird plastic-like smell”
- “Smells a bit like stale chemicals”
- “No fragrance, but the natural scent is off-putting”
- “Smells medicinal in a bad way”
Sources: lovi.care, ulta.com, sephora.com, clinique.com, amazon.com, makeupalley.com, and more
Questions and answers
How well does Clinique Dramatically Different Moisturizing Lotion+ work for dry sensitive skin?
This moisturizer works decently for dry sensitive skin by giving you moderate hydration and helping to lock in moisture. However, a product of this type needs rich, deeply nourishing ingredients, powerful moisture-binding agents, and skin barrier support without any risk of irritation to truly fit this skin type best.
Which ingredients make this cream a good fit for dry sensitive skin?
Glycerin, sodium hyaluronate, petrolatum, mineral oil, and urea make this cream a good fit by providing moisture and helping to keep it locked in. These ingredients help improve hydration and support dry or flaky skin. To fit dry sensitive skin best, a product of this type needs highly effective, soothing ingredients that provide deep hydration and nourishment without any risk of irritation, alongside barrier-supporting components and the absence of allergens.
What does Glycerin do for dry sensitive skin?
Glycerin helps dry sensitive skin by drawing moisture into the skin and keeping it there, making the skin soft and smooth. It is very gentle and unlikely to cause irritation while improving how well the skin holds onto water. This type of skin needs ingredients that boost hydration and repair the barrier without causing stinging.
Clinical, Cosmetic and Investigational Dermatology, 2017The British Journal of Dermatology, 2008
What does Hyaluronic Acid do for dry sensitive skin?
Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Journal of Drugs in Dermatology, 2011Dermatology and Therapy, 2021
Where does it go in a skincare routine for dry sensitive skin?
Apply this moisturizer in the evening as the last step after your cleanser, toner, and treatment. A product of this type needs richer barrier-repairing ingredients and targeted soothing benefits for dry and sensitive skin.
The Journal of Dermatological Treatment, 2022Clinical, Cosmetic and Investigational Dermatology, 2017
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying your retinol first and following with this moisturizer once it absorbs to help calm and protect your dry and sensitive skin. Moisturizers that help restore the skin barrier may make it easier for your skin to adjust to retinol.
How often should I use it?
You can use this moisturizer twice a day to keep your dry sensitive skin comfortable. Regular daily application helps lock in moisture and supports your skin barrier.
Can this cream clog pores, cause breakouts or purging for dry sensitive skin?
This cream may cause breakouts for some people with dry sensitive skin, as reviewers moderately complain about breakouts and the formula includes mineral oil and petrolatum. Skin of this type needs lightweight hydrators and non-pore-clogging barrier ingredients that deeply nourish without heavy oils.
Can I use it around the eyes or on my body?
This moisturizer is safe to use on the thin skin around the eyes and on the body, though dry sensitive skin needs extra soothing ingredients and richer moisture to stay soft and smooth.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical application of sesame oil combined with standard care significantly reduced infusion-related phlebitis in adults compared to a control condition, with a risk ratio of 0.54.
Complementary Therapies in Medicine, 2025Sesamol loaded silver nanoparticles gel showed a twofold increase in skin permeation and higher antioxidant activity compared to conventional formulations, demonstrating potential for topical wound healing delivery.
Current Pharmaceutical Design, 2024Treatment with moderately ozonated sesame oil accelerates cutaneous wound closure and enhances cell response, angiogenesis, and VEGF and cyclin D1 expression in SKH1 mice compared to oil with lower or higher peroxide values and controls.
Wound Repair and Regeneration, 2011Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls.
International Journal of Biological Macromolecules, 2024Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream.
Endocrine, Metabolic & Immune Disorders Drug Targets, 2021Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats.
The International Journal of Lower Extremity Wounds, 2024
Why other moisturizers fit dry sensitive skin better
Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016
Ingredients
Water, Mineral Oil, Paraffinum Liquidum, Huile Minérale, Glycerin, Petrolatum, Stearic Acid, Glyceryl Stearate, Sesamum Indicum Oil, Urea, Lanolin Alcohol, Triethanolamine, Hordeum Vulgare Extract, Extrait Dorge, Cucumis Sativus Fruit Extract, Helianthus Annuus Seedcake Sunflower Seedcake, Propylene Glycol Dicaprate, Sodium Hyaluronate, Butylene Glycol, Pentylene Glycol, Trisodium Edta, Phenoxyethanol, Ci 15985, Yellow 5 Ci 19140, Red 33 Ci 17200
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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