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Theramid Copper Peptide for combination skin

Theramid Copper Peptide

High

  • HighCombination Skin Fit
  • AverageEffectiveness
  • HighSafety

A great choice for combination skin; a few serums fit it even better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Highly suitable for your combination skin, this product leverages copper tripeptide-1 and bifida lysate ferment to boost collagen and repair your skin barrier, addressing fine lines and wrinkles effectively.
  • While it offers excellent hydration and anti-aging benefits, it lacks specialized ingredients to directly target oily shine, which is your main concern.
  • The formulation is safe for your combination skin, containing no harsh or prohibited ingredients that could cause irritation.

How to apply

  • Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
  • Apply the serum after cleansing and toner, and right before your moisturizer.
  • Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
  • Apply the serum on clean and dry skin since your skin is not sensitive.
  • Always do a patch test before using the serum for the first time, and avoid the eye area .

People Say

★4.4Overall rating based on 100+ reviews

A lightweight, fast-absorbing texture is frequently praised, and a moderate number of users report a boost in skin radiance. Some users find the high silicone content problematic for layering and note that copper peptides require careful routine planning to avoid conflicts with other active ingredients.

Highlights

  • Improves firmness Often Mentioned
    • “my skin feels incredibly fed and plump”
    • “improving skin elasticity and firmness”
    • “it felt bouncier and more lifted”
    • “helps to improve signs of aging... firm, smooth, radiant, and younger-looking skin”
  • Lightweight, fast-absorbing Often Mentioned
    • “the texture is a sophisticated, lightweight gel that absorbs almost instantly without leaving a sticky residue”
    • “absorbs quickly, and doesn't leave any stickiness, which is a huge plus for those of us who prefer to layer products”
    • “it feels better on my skin... soaks in much better”
    • “light, gel-like consistency absorbs quickly without leaving a tacky residue”
  • Boosts radiance Sometimes Noted
    • “instantly gives the skin a radiant glow and freshness”
    • “my skin has gotten a lot brighter and a lot better”
    • “helps my complexion look lively”
    • “promote a more youthful glow”
  • Gentle, non-irritating Sometimes Noted
    • “incredibly gentle... I experienced zero redness or irritation”
    • “I experienced no redness or dryness, which is often a concern when introducing strong active ingredients”
    • “perfect for beginners, sensitive skin”
  • Hard to combine Sometimes Noted
    • “copper peptides are high maintenance... you really don't want to use it in with anything that has a low pH”
    • “I wouldn't recommend using it together with Niactilen”
    • “Do not use with other acids and retinol products”
  • High silicone content Rarely Noted
    • “I don't like the fact that is has so much silicone in it”
    • “makes it very difficult to rub on the skin, because it 'sticks' to first place you put it and doesn't blend well”
    • “This broke me out on my face”
  • No visible results Rarely Noted
    • “Nearly 2 months in, no result”
    • “No Effect”
    • “I have it, I can't say how effective it is”

Sources: lovi.care, peptides133.com, peptides136.com, peptides138.com, youtube.com, lyko.com, and more

Questions and answers

What makes Theramid Copper Peptide serum a great fit for combination skin?

Theramid Copper Peptide serum is a great fit for combination skin because it uses copper tripeptide-1 and bifida lysate ferment to boost collagen, repair your skin barrier, and smooth fine lines. It also provides strong hydration while maintaining a very safe profile that is unlikely to cause irritation.

Skin Research and Technology, 2026Journal of Cosmetic Dermatology, 2023

Which ingredients make this serum a good fit for combination skin?

Copper Tripeptide-1 and Bifida Lysate Ferment make this serum a great fit for your combination skin because they help boost collagen and repair your skin barrier. They improve fine lines while keeping your skin calm and protected without causing irritation.

Skin Research and Technology, 2026Journal of Cosmetic Dermatology, 2023

What does Copper Tripeptide-1 do for combination skin?

Copper Tripeptide-1 helps calm combination skin, smooth fine lines, and support a strong skin barrier. It protects against sun damage and helps tighten the skin, keeping it looking firm and healthy.

Skin Research and Technology, 2026BioMed Research International, 2015

What does Acetyl Tetrapeptide-2 do for combination skin?

Acetyl Tetrapeptide-2 helps strengthen the skin and maintains its firmness across different areas of combination skin. This ingredient is well suited for daily use to support elasticity and keep the skin looking firm.

International Journal of Peptide Research and Therapeutics, 2018

Where does this serum go in a skincare routine for combination skin?

This treatment goes in your evening routine, applied after cleansing and toning and before your moisturizer. Treatments are placed in the evening for simplicity and extra safety around sun exposure, though some may also be used in the morning or twice a day.

Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it first to give your skin a boost of hydration and repair, followed by your retinol once it is fully absorbed. This combination is generally safe and unlikely to cause irritation, helping to smooth fine lines while keeping your skin barrier protected.

Skin Research and Technology, 2026Journal of Cosmetic Dermatology, 2023

How often should I use this serum?

You can use this treatment in your evening routine, applying it after cleansing and toning and before moisturizing. It is safe for daily use on combination skin, helping to smooth fine lines and strengthen your skin barrier without causing irritation.

Skin Research and Technology, 2026Journal of Cosmetic Dermatology, 2023

Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on your combination skin because it contains no harsh or prohibited ingredients that could cause irritation. It also features a safe formulation with a low likelihood of adverse reactions.

Skin Research and Technology, 2026Journal of Cosmetic Dermatology, 2023

Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality.

    Archives of Facial Plastic Surgery, 2006
  • A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days.

    Cureus, 2024
  • The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls.

    Skin Research and Technology, 2026
  • Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls.

    International Journal of Peptide Research and Therapeutics, 2018
  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011
  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022
  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019
  • Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.

    Journal of Cosmetic Dermatology, 2023

Ingredients

Water, Propanediol, Cyclopentasiloxane, Dimethicone, Betaine, Copper Tripeptide-1, Bifida Lysate Ferment, Cyclohexasiloxane, Glycerin, Sodium Chloride, Polyglyceryl-4 Isostearate, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-1, Bacillus Folic Acid Extract Ferment Filtrate, Cetyl Peg Ppg-10 1 Dimethicone, Hexyl Laurate, Peg Ppg-18 18 Dimethicone, Lecithin, Acetyl Glutamine, Caprylyl Glycol, Butylene Glycol, Dextran, Disodium Edta, Acetic Acid, Lactic Acid, 1,2-Hexanediol, Sodium Benzoate, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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