MISSHA Time Revolution Night Repair Ampoule Cream 5X for mature skin
Extreme Biome
Bifida Lysate Ferment
Niacinamide
Centella Asiatica Extract
Ceramide Np
Low
- LowNormal Skin Fit
- AverageEffectiveness
- Low RiskSafety
A weak match for mature skin; the moisturizers alongside fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for normal skin due to the presence of glycerin and biosaccharide gum-1 with humectant action, but lacks sufficient potent actives for optimal benefit in addressing wrinkles and fine lines.
- The formula provides excellent moisturizing and treatment with glycerin and niacinamide, which hydrate and smooth texture, supporting your skin's barrier function.
- The product is generally safe for your normal skin, though alcohol and fragrance may pose a slight risk of irritation.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.6Overall rating based on 400+ reviewsThis anti-aging night cream is highly effective for dry and mature skin, providing deep hydration and plumping for a softer, glowing, and more elastic complexion. While many users appreciate its rich, nourishing texture and good value, some with oily or acne-prone skin find it too heavy and occasionally experience breakouts or a greasy finish.
Highlights
Deeply moisturizing Mostly Mentioned
- “deeply hydrates and smooths”
- “perfect for dry skin in winter”
- “woke up with plump skin”
- “skin feels velvety soft”
Improves texture Often Mentioned
- “restores elasticity”
- “skin looks younger”
- “refines skin texture”
- “makes face glowy”
Good value Sometimes Noted
- “great value for money”
- “better than expensive brands”
- “affordable anti-aging”
- “high quality ingredients”
Rich consistency Sometimes Noted
- “rich nourishing formula”
- “thick but spreads well”
- “feels luxurious”
- “comforting night cream”
Heavy or greasy Sometimes Noted
- “excessively oily”
- “sits on top of skin”
- “sticky residue”
- “transfers to pillow”
Fragrance sensitivity Rarely Noted
- “scent is too strong”
- “smells like herbs”
- “irritating fragrance”
- “prefer unscented”
Packaging concerns Rarely Noted
- “jar packaging hygiene concerns”
- “heavy glass jar”
- “prefer a pump”
- “hard to gauge amount left”
Potential breakouts Rarely Noted
- “caused blemishes”
- “cheeks broke out”
- “too rich for my pores”
- “led to small bumps”
Sources: lovi.care, sokoglam.com, iherb.com, target.com, misshaus.com, hwahae.co.kr, and more
Questions and answers
Why is Missha Night Repair Ampoule Cream 5X a weak match for mature skin?
This cream is a weak match for mature skin because it lacks sufficient potent actives for optimal benefit in addressing wrinkles and fine lines. A moisturizing treatment for mature skin needs strong anti-aging actives like peptides and targeted firming ingredients to smooth fine lines and support aging skin.
Journal of Cosmetic Dermatology, 2021Scientific Reports, 2024
Which ingredients make this cream a poor fit for mature skin?
This cream is a weak match for mature skin because it lacks sufficient potent actives to effectively address wrinkles and fine lines. A moisturizing treatment for mature skin needs powerful anti-aging ingredients and peptides that specifically target and smooth fine lines while supporting overall skin firmness.
Journal of Cosmetic Dermatology, 2021Scientific Reports, 2024
What does Extreme Biome do for mature skin?
Extreme Biome helps maintain skin hydration, tone, and radiance while normalizing the skin microbiome and improving physiology in mature skin. Regular use supports skin defenses and helps reduce visible signs of aging.
What does Bifida Ferment Lysate do for mature skin?
Bifida Ferment Lysate helps strengthen the skin barrier and calm irritation, which keeps mature skin feeling soft and comfortable. It also provides antioxidant support that may protect against everyday stress, though products for mature skin also need firming and smoothing ingredients like peptides and retinol.
Journal of Cosmetic Dermatology, 2023Experimental Dermatology, 2010
Where does this cream go in a skincare routine for mature skin?
This moisturizing treatment goes in the evening routine after cleansing and before your final moisturizer. A product for mature skin needs potent anti-aging actives like peptides and antioxidants to effectively help address wrinkles and fine lines.
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying the cream after your retinol to help cushion your skin against dryness. This type of routine benefits from a moisturizer that contains extra firming peptides, powerful antioxidants, and concentrated anti-aging ingredients to smooth lines.
How often should I use this cream?
This cream is a weak match for mature skin because it lacks sufficient potent actives to effectively target wrinkles and fine lines, and products of this type need stronger wrinkle-smoothing ingredients and deeply nourishing elements for this skin. For best results, use a moisturizing treatment packed with peptides, retinoids, or potent antioxidants to properly care for mature skin.
Can this cream clog pores, cause breakouts or purging for mature skin?
This cream is unlikely to cause breakouts for mature skin, though some reviewers have reported a heavy or greasy feel. To properly care for mature skin, a product of this type needs potent anti-aging ingredients like peptides, retinol, or antioxidants to target wrinkles and fine lines.
Can I use this cream around the eyes or on my body?
This cream is a weak match for mature skin because it lacks sufficient potent actives to effectively address wrinkles and fine lines. A moisturizing treatment for mature skin needs strong anti-aging ingredients like peptides, retinoids, or concentrated antioxidants to smooth lines and firm the skin.
Is this cream fragrance-free and alcohol-free?
It has no fragrance and contains drying alcohol (alcohol).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.
Scientific Reports, 2024Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate can be used safely in cosmetic formulations at concentrations up to 5%, and Benzyl Alcohol is safe up to 10% in hair dyes, despite causing nonimmunologic contact reactions.
International Journal of Toxicology, 2001Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline.
Journal of Cosmetic and Laser Therapy, 2006Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.
Experimental Dermatology, 2008
Why other moisturizers fit mature skin better
Combining oral and topical astaxanthin in 30 healthy females improved skin wrinkles, age spots, elasticity, texture, and moisture, while 6 mg daily oral supplementation in 36 healthy males improved crow's feet wrinkles, elasticity, and transepidermal water loss.
Acta Biochimica Polonica, 2012Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019A supramolecular system of malic acid-derived ionic liquid and acetyl hexapeptide-8 enhanced transdermal permeation by 3.10 times, increased collagen production, inhibited acetylcholine release, and reduced wrinkle number, length, and area compared to peptide monotherapy in human subjects.
Journal of Materials Chemistry. B, 2025
Ingredients
Water, Glycerin, Methyl Propanediol, Cyclohexasiloxane, Hydrogenated Polyisobutene, Caprylic Capric Triglyceride, Triethylhexanoin, Cetearyl Alcohol, Niacinamide, Dimethicone, 1,2-Hexanediol, Trehalose, Stearyl Alcohol, Beeswax, Cetyl Alcohol, Phytosteryl Isostearyl Cetyl Stearyl Behenyl Dimer Dilinoleate, Cetearyl Glucoside, Vinyl Dimethicone, Polyglyceryl-2 Stearate, Glyceryl Stearate, Palmitic Acid, Stearic Acid, Bergamot Oil Fruit, Hydroxyacetophenone, Dioscorea Japonica Root Extract, Ammonium Acryloyldimethyltaurate Vp Copolymer, Ethylhexylglycerin, Glycosyl Trehalose, Butylene Glycol, Alcohol, Bifida Lysate Ferment, Hydrogenated Hydrolysate Starch, Xanthan Gum, Adenosine, Raffinose, Glyceryl Polymethacrylate, Dextrin, Theobroma Cacao Shell Powder, Pelargonium Graveolens Oil Flower, Lecithin, Disodium Edta, Hydrogenated Lecithin, Camellia Sinensis Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Helianthus Annuus Seed Oil Sunflower Seed Oil, Jojoba Seed Oil, Camellia Japonica Seed Oil, Macadamia Ternifolia Seed Oil, Glucose, Centella Asiatica Extract, Ficus Carica Fruit Extract, Polyquaternium-51, Cetearyl Olivate, Ceramide Np, Lavandula Angustifolia Oil Lavender Oil, Citrus Aurantium Dulcis Peel Oil, Sorbitan Olivate, Phellodendron Amurense Bark Extract, Lactobacillus Ferment, Myristic Acid, Lactobacillus Acerola Cherry Ferment, Lactococcus Ferment, Leuconostoc Radish Root Ferment Filtrate, Bifida Ferment Filtrate, Lactobacillus Soybean Extract Ferment, Lactobacillus Punica Granatum Extract Fruit Ferment, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Monascus Extract, Sucrose Distearate, Rice Extract, Dipropylene Glycol, Biosaccharide Gum-1, Saccharomyces Ferment, Beta Vulgaris Root Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Brassica Oleracea Capitata Leaf Extract, Blueberry Fruit Extract, Solanum Melongena Fruit Extract, Anthemis Nobilis Oil Flower, Tocopherol, Sandalwood Oil, Bacillus Ferment
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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