Murad Retinol Youth Renewal Serum for mature skin

How to apply

Questions and answers

What the research says

• Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.

  International Journal of Cosmetic Science, 2017

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Urea is a safe and effective dermatologic therapy with wide-ranging clinical utility for various skin conditions and minimal, non-systemic side effects based on a review of the clinical literature.

  Dermatology Online Journal, 2013

• Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.

  The British Journal of Dermatology, 2019

• Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.

  Journal of Controlled Release, 2018

• Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle.

  Archives of Dermatological Research, 2017

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Water, Cyclopentasiloxane, Isopropyl Palmitate, C14-22 Alcohols, Polymethylsilsesquioxane, Dimethicone, Propanediol, Glyceryl Stearate, Peg-100 Stearate, Shea Ethyl Esters Butter, Retinol, Hydroxypinacolone Retinoate, Ceramide Np, Sodium Hyaluronate, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Swertia Chirata Extract, Squalane, Punica Granatum Extract, Tocopheryl Acetate, Glycine Soja Extract Soybean Extract, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Glycerin, Caprylic Capric Triglyceride, Dimethyl Isosorbide, Silica, Ethylhexyl Palmitate, Silica Dimethyl Silylate, Butylene Glycol, Lecithin, Ammonium Acryloyldimethyltaurate Vp Copolymer, C12-20 Alkyl Glucoside, Cetyl Palmitate, Laureth-23, Polysorbate 20, Trideceth-6 Phosphate, Synthetic Fluorphlogopite, Phenoxyethanol, Ethylhexylglycerin, Chlorphenesin, Disodium Edta, Sodium Hydroxide, Tris Tetramethylhydroxypiperidinol Citrate, Sodium Benzotriazolyl Butylphenol Sulfonate, Titanium Dioxide Ci 77891, Red 4 Ci 14700, Alpha-Isomethyl Ionone, Citronellol, Parfum

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.