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ISDIN vs Sebamed

Rated by Lovi 路 Unbiased, science-based skincare AI trained on real user outcomes 路 How the Fit score works

ISDIN and Sebamed are well-regarded European skincare houses rooted in decades of dermatological heritage, with the former originating in Spain in 1975 and the latter founded in Germany in 1967. ISDIN delivers sophisticated moisturizers, sunscreens, serums, and eye products that suit acne-prone and combination skin best, while Sebamed offers gentle cleansers and moisturizers relying on skin-neutral pH to suit sensitive, reactive, and problematic skin. Both provide reliable, gentle efficacy through daily use, though they differ as the Spanish brand emphasizes advanced blends for concerns like dark spots and mature skin, whereas the German brand maintains a steady focus on barrier health.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

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Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG.

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This page compares some of the most popular ISDIN and Sebamed products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular ISDIN vs Sebamed products

Questions and answers

ISDIN or Sebamed: which is better?

ISDIN fits acne-prone, combination, and sensitive skin best on this page, while Sebamed has fewer options and lacks defined brand-focused routines. ISDIN offers ultralight sunscreens and lightweight moisturizers, though reviewers often mention its high price point.

What is the difference between ISDIN and Sebamed?

ISDIN offers a larger variety of products on this page across categories like sunscreens and serums with fit levels up to Superior, whereas Sebamed features only a moisturizer and a cleanser with high and average fits. Every product on the Sebamed page lists no fragrance, while several ISDIN products contain fragrance.

ISDIN or Sebamed: which moisturizer is better?

When comparing moisturizers, ISDIN offers options like Hyaluronic Concentrate with High fit for sensitive and acne-prone skin, whereas Sebamed provides the Clear Face Care Gel, which has a High fit specifically for oily acne-prone skin. Sodium hyaluronate helps improve skin quality and signs of aging.

Dermatologic Therapy, 2022

Which is more affordable, ISDIN or Sebamed?

Sebamed products on this page are more affordable, whereas ISDIN has a high price point.

Which causes fewer breakouts, ISDIN or Sebamed?

Sebamed products on this page list no fragrance, which helps reduce the likelihood of irritation that can lead to breakouts. ISDIN offers high fit levels for acne-prone skin with products like Eryfotona Actinica and Fusion Water, though several of its formulas contain fragrance.

Between ISDIN and Sebamed, which brand offers fragrance-free products?

Sebamed offers fragrance-free products since every product on this page lists no fragrance in its ingredients, whereas 5 of the 8 ISDIN products on this page contain fragrance. Sodium hyaluronate in ISDIN formulas helps improve skin quality.

Dermatologic Therapy, 2022

How do the founding years and countries of origin compare between ISDIN and Sebamed?

ISDIN was founded in 1975 in Spain, whereas Sebamed was founded in 1967 in Germany.

Which brand has a higher Lovi fit level for mature skin, ISDIN or Sebamed?

ISDIN has a higher Lovi fit level for mature skin, offering Superior fit with Eryfotona Actinica and High fit with Fusion Water, K-Ox Eyes, Flavo-C Serum, and Retinal Intense Serum, whereas Sebamed products on this page have an Average fit level for mature skin.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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