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Estée Lauder vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Estée Lauder and Sesderma are distinguished skincare brands rooted in heritage and scientific research, with the American pioneer founded in 1946 and the Spanish innovator established in 1989. The former is beloved for its comprehensive range of moisturizers, serums, eye products, and cleansers formulated with hydrating hyaluronic acid and glycerin, which suit acne-prone and mature skin best. Meanwhile, the latter is known for its advanced serums and meticulously engineered formulas that best suit sensitive, hyperpigmented, and aging skin types. Ultimately, while both brands offer standout treatments like the Micro Essence Treatment Lotion and the Azelac RU Serum to refine skin texture and promote a radiant complexion, they differ in their origin, founding eras, and specific active compounds.

Estée Lauder is an American skincare brand founded in 1946 and owned by The Estée Lauder Companies Inc..

en.wikipedia.orgelcompanies.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Estée Lauder and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Estée Lauder vs Sesderma products

Questions and answers

What is the difference between Estée Lauder and Sesderma?

Estee Lauder is a much larger US brand founded in 1946 with a broad range of fourteen products on this page featuring key ingredients like hyaluronic acid and glycerin, whereas Sesderma is a Spanish brand founded in 1989 with only one product listed here, the Azelac RU Serum.

Journal of Pharmacy & Pharmaceutical Sciences, 2015Dermatologic Therapy, 2022

Which is more affordable, Estée Lauder or Sesderma?

Reviewers frequently note that Estée Lauder has a high price point. The page facts do not provide pricing information for Sesderma.

Which causes fewer breakouts, Estée Lauder or Sesderma?

Among the products on this page, Estee Lauder features multiple options rated High or Superior for acne-prone skin, whereas Sesderma offers Azelac RU Serum with a High fit for acne-prone skin. Both brands provide formulations that help target breakouts effectively.

Which brand has been established longer, Estée Lauder or Sesderma?

Estée Lauder has been established longer, having been founded in the United States in 1946, whereas Sesderma was founded in Spain in 1989.

How many products from Estée Lauder and Sesderma contain fragrance according to the page?

According to the page, two products from Estée Lauder contain fragrance, which are DayWear Moisturizer and Soft Clean Moisture Rich Foaming Cleanser. For Sesderma, the single product on the page, Azelac RU Serum, also lists fragrance.

What key ingredients are found across the products of Estée Lauder?

The key ingredients found across the products on this page for Estée Lauder are hyaluronic acid and glycerin. Topical hyaluronic acid helps improve skin quality and signs of skin aging.

Dermatologic Therapy, 2022

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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