UpCircle Eye Cream for mature skin

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical treatment with a phytocosmetic preparation containing Myrothamnus flabellifolia and Coffea arabica improved skin aging and pigmentation signals in human volunteers by modulating the ubiquitin-proteasome and autophagy processes.

  Journal of Cosmetic Dermatology, 2022

• A novel phenolic antioxidant skin care system significantly improved the appearance of wrinkles, firmness, hyperpigmentation, blotchy redness, tactile roughness, and clarity in photodamaged skin compared to a control regimen in 40 Caucasian female participants over 12 weeks.

  Journal of Drugs in Dermatology, 2010

• Green Coffea arabica L. seed oil dose-dependently stimulated collagen, elastin, and glycosaminoglycan synthesis, increased TGF-beta1 and GM-CSF release in human fibroblasts, and induced AQP-3 mRNA expression up to 6.5-fold in keratinocytes compared to control cultures.

  Journal of Cosmetic Dermatology, 2009

• Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls.

  International Journal of Biological Macromolecules, 2024

• Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream.

  Endocrine, Metabolic & Immune Disorders Drug Targets, 2021

• Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats.

  The International Journal of Lower Extremity Wounds, 2024

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

Why other eye cares fit mature skin better

• Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects.

  International Journal of Cosmetic Science, 2014

• Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.

  The British Journal of Dermatology, 2019

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

Ingredients

Water, Butyrospermum Parkii Butter Shea Butter, C14-22 Alcohols, C12-20 Alkyl Glucoside, Glycerin, Cucumis Sativus Fruit Extract, Helianthus Annuus Seed Oil, Vitis Vinifera Seed Oil Grape Seed Oil, Acer Rubrum Extract Maple Extract, Coffea Arabica Seed Extract Coffee Seed Extract, Sodium Hyaluronate, Calendula Officinalis Extract, Anthemis Nobilis Oil Flower Chamomile Oil Flower, Olea Europaea Oil Fruit Olive Oil Fruit, Rosmarinus Officinalis Leaf Extract, Tocopherol, Citric Acid, Salicylic Acid, Sorbic Acid, Potassium Sorbate, Benzyl Alcohol, Limonene

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.