Sarah Chapman Eye Recovery for mature skin

Questions and answers

What the research says

• Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects.

  International Journal of Cosmetic Science, 2005

• Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.

  Colloids and Surfaces. B, Biointerfaces, 2025

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• A formulation combining 4-hexylresorcinol and niacinamide significantly improved hyperpigmentation, skin tone, fine lines, wrinkles, and firmness compared to niacinamide alone in Chinese subjects without adverse events.

  International Journal of Cosmetic Science, 2022

• Topical 1% hexylresorcinol is equivalent to 2% hydroquinone in significantly reducing the appearance of facial and hand pigmentation in healthy female participants over 12 weeks, with both treatments showing no adverse effects.

  Archives of Dermatological Research, 2023

• A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation.

  International Journal of Cosmetic Science, 2024

• Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question.

  The Journal of Clinical and Aesthetic Dermatology, 2021

• A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women.

  The British Journal of Dermatology, 2010

• Topical retinyl propionate cream produced no statistically significant differences compared to placebo for any clinical, histological, or profilometric parameters of skin photoageing in 80 subjects.

  Clinical and Experimental Dermatology, 1998

Ingredients

Water, Glycerin, Cetearyl Olivate, Isopropyl Palmitate, Phenyl Trimethicone, Sorbitan Olivate, Butylene Glycol, Caprylic Capric Triglyceride, Cetearyl Alcohol, Dimethicone, Cetyl Alcohol, Glyceryl Stearate, Peg-100 Stearate, Sodium Hyaluronate Crosspolymer, Tetrahexyldecyl Ascorbate, Plantago Lanceolata Leaf Extract, Crithmum Maritimum Extract, Hesperidin Methyl Chalcone, Teprenone, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, N-Hydroxysuccinimide, Dipeptide-2, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Chrysin, Palmitoyl Tripeptide-1, Dicetyl Phosphate, Ceteth-10 Phosphate, Steareth-20, Acetyl Tyrosine, Proline, Hydrolyzed Protein, Adenosine Triphosphate, Ethylhexyl Palmitate, Silica Dimethyl Silyate, Sodium Hyaluronate, Hexylresorcinol, Cyclopentasiloxane, Ppg-12 Smdi Copolymer, Triethanolamine, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Saccharide Isomerate, Xanthan Gum, Dimethylaminoethanol Tartrate, Stearyl Glycyrrhetinate, Retinyl Palmitate, Thioctic Acid, Carnosine, Ubiquinone, Tocopheryl Acetate, Tricholoma Matsutake Extract, Sandalwood Extract, Phellodendron Amurense Bark Extract, Hordeum Distichon Extract, Mica, Iris Florentina Root Extract, Jasmine Flower Extract, Lilium Candidum Bulb Extract, Dipotassium Glycyrrhizate, Aloe Barbadensis Leaf Juice Powder, Polysorbate 20, Peg-8, Tocopherol, Ascorbyl Palmitate, Ascorbic Acid, Citric Acid, Silica, Carbomer, Disodium Edta, Bismuth Oxychloride, Ci 77891

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.