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Perricone MD Rejuvenating Moisturizer for combination skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Perricone MD Rejuvenating Moisturizer

Average

  • AverageCombination Skin Fit
  • AverageEffectiveness
  • Low RiskSafety

Works for combination skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate moisturizing for your combination skin, with glycerin and dimethicone providing hydration and smoothing, but it lacks specialized ingredients to effectively address oily shine.
  • Tetrahexyldecyl ascorbate offers antioxidant benefits, while lactic acid can help with texture, though these may not fully balance the needs of both oily and dry areas.
  • The product is generally safe for your combination skin, with minimal risks of irritation from lactic acid and parfum.

How to apply

  • Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
  • Apply this moisturizer after your cleanser and toner, right before your morning SPF.
  • Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
  • Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
  • Avoid the eye area when applying the moisturizer. Do a patch test before your first use.

People Say

★4.6Overall rating based on 1.0k+ reviews

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

Highlights

  • Deeply hydrating Often Mentioned
    • “Keeps my skin moist without the acne.”
    • “Very rich and nourishing.”
    • “Replenishes fragile skin.”
  • Improves texture Often Mentioned
    • “Skin looks smoother, with no discoloration.”
    • “Visibly plumper, firmer, and smoother.”
    • “Skin feels better, smoother and brighter.”
  • Non-greasy formula Sometimes Noted
    • “It's non greasy, absorbs right in.”
    • “Absorbs quickly without any residual grease.”
    • “Not greasy or sticky.”
  • Reduces lines Sometimes Noted
    • “Plumps my skin to reduce the look of fine lines.”
    • “Targets deep wrinkles and creases.”
    • “Saw a reduction in the appearance of fine lines.”
  • Product pilling Sometimes Noted
    • “When I try to apply my liquid makeup over it it rolls up.”
    • “It all pealed away. It looked like a snow storm.”
    • “I do not really experience pilling unless I use too much.”
  • Fragrance sensitivity Rarely Noted
    • “A few reviewers found the fragrance too strong.”
    • “Unfortunately had an allergic reaction.”
    • “Experienced minor irritation.”
  • White cast Rarely Noted
    • “Leaves this white flaky texture on my face.”
    • “Had to really blend so it didn't appear to leave a white cast.”
    • “Doesn't leave a whitecast (after 7 days).”

Sources: lovi.care, perriconemd.com, lovelyskin.com, walmart.com, ipsy.com, nordstrom.com, and more

Questions and answers

How well does Perricone MD Rejuvenating Moisturizer work for combination skin?

This moisturizer works reasonably well for combination skin by providing moderate hydration and smoothing, though it lacks specialized ingredients to effectively control oily shine in the T-zone. Combination skin of this type needs balanced formulas containing targeted brightening agents and oil-controlling ingredients to manage both dry and oily areas without causing heaviness or irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for combination skin?

Glycerin and dimethicone help hydrate and smooth your skin, while tetrahexyldecyl ascorbate provides antioxidants. However, because this product lacks specialized ingredients to control oily shine, combination skin needs a treatment with ingredients that target both oil control and balanced hydration.

Clinical, Cosmetic and Investigational Dermatology, 2017Ostomy/wound Management, 2005

What does Acyl-Glutathione do for combination skin?

Acyl-Glutathione helps brighten skin color and smooth out wrinkles while keeping combination skin hydrated. Topical use of glutathione may improve dark spots and reduce water loss, though its overall effect can vary from person to person.

The Journal of Clinical and Aesthetic Dermatology, 2025Journal of Cosmetic Dermatology, 2019

What does Vitamin C do for combination skin?

Vitamin C helps brighten combination skin, smooth out uneven texture, and protect against daily environmental stress while keeping it balanced. It may also improve hydration and reduce redness in areas that tend to be dry or irritated.

Journal of Cosmetic Dermatology, 2024Photochemistry and Photobiology, 2021

Where does it go in a skincare routine for combination skin?

This moisturizer goes in the morning routine after your hydrating toner and SPF, and in the evening routine as the final step. A product of this type for combination skin needs ingredients that provide balanced hydration and help manage oily shine.

Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the retinol first and following it with this moisturizer to help keep your skin comfortable and smooth. Combination skin requires a moisturizer that balances dry patches while managing oily shine.

How often should I use it?

You can use this moisturizing treatment twice daily as part of your morning and evening routine. Regular daily application helps improve skin moisture, smoothness, and overall texture while keeping your skin barrier supported.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to clog pores or cause breakouts on combination skin, though it may not fully control oily shine. A product for this skin needs lightweight hydration and balancing ingredients that manage both dry patches and excess oil without feeling heavy.

Clinical, Cosmetic and Investigational Dermatology, 2017Ostomy/wound Management, 2005

Can I use it around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as its safety profile supports general application. However, a product of this type needs lighter hydration and oil-balancing ingredients to properly care for thin eye skin and varied body areas.

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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