BIOEFFECT EGF Power Serum for oily acne-prone skin
Rh-Oligopeptide-1
Sodium Hyaluronate
Acetyl Glucosamine
Hordeum Vulgare Seed Extract
Glycerin
Average
- HighOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily acne-prone skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent skin regeneration for your oily skin due to the presence of Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1 and Kgf Barley Sh-Polypeptide-3, which are beneficial for treating skin concerns.
- Glycerin and Sodium Hyaluronate provide hydration suitable for oily skin, though they offer limited direct benefits for your specific concerns of acne, blemishes, and breakouts.
- The product is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.7Overall rating based on 100+ reviewsThis serum is highly effective for mature, dry, and aging skin, with users frequently reporting improvements in texture, firmness, and radiance. Based on limited data, the product is praised for visibly reducing fine lines and hyperpigmentation, leaving the complexion plumper and more even-toned. Some users note a tacky feel after application and that results require patience, while the high price point is a common concern.
Highlights
Improves skin texture Mostly Mentioned
- “Skin feels smoother”
- “texture has improved”
- “skin is plumper”
High price point Mostly Mentioned
- “Very pricey”
- “could not have afforded”
- “worth every penny but expensive”
Boosts skin radiance Often Mentioned
- “Skin looks glowing”
- “complexion more radiant”
- “beaming skin”
Reduces fine lines Often Mentioned
- “Laugh lines less obvious”
- “wrinkles less visible”
- “targets fine lines”
Deeply hydrating Sometimes Noted
- “Instant hydration boost”
- “sealing in moisture”
- “great for dehydrated skin”
Gentle formula Sometimes Noted
- “Great on sensitive skin”
- “no breakouts”
- “non-irritating”
Requires patience Sometimes Noted
- “Takes weeks to notice”
- “not instant results”
- “cumulative improvements”
Tacky skin feel Sometimes Noted
- “Sticky for 30 mins”
- “tacky feel after application”
Limited care feeling Rarely Noted
- “Doesn't feel 'creamed'”
- “need extra moisturizer”
- “not enough for some”
Sources: lovi.care, bioeffect.com, dermstore.com, whowhatwear.com, joannaczech.com, katiesnooks.com, and more
Questions and answers
How well does BIOEFFECT EGF Power Serum work for oily acne-prone skin?
This serum works moderately well for oily acne-prone skin, providing safe hydration and skin renewal without causing irritation, though it does little for breakouts. Treatments that fit this skin better need ingredients like niacinamide, propolis, or vitamin C to control excess oil and target acne while keeping the skin comfortable.
Which ingredients make this serum a good fit for oily acne-prone skin?
Rh-Oligopeptide-1, glycerin, and sodium hyaluronate make this serum a fit by offering skin regeneration and hydration, though it lacks specific ingredients for acne like niacinamide or vitamin C. A product for this skin needs ingredients that target excess oil and blemishes while remaining lightweight and non-irritating.
What does EGF do for oily acne-prone skin?
EGF helps calm redness and breakouts, and it may improve the look of acne scars on oily skin. It also supports the skin barrier while increasing skin water and oil balance.
Clinical, Cosmetic and Investigational Dermatology, 2023International Journal of Dermatology, 2014
What does Hyaluronic Acid do for oily acne-prone skin?
Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
The Journal of Investigative Dermatology, 2017Journal of Cosmetic Dermatology, 2022
Where does this serum go in a skincare routine for oily acne-prone skin?
This serum goes in your evening routine after cleansing and before moisturizing. It is safe for oily skin and helps renew the skin, though an oily acne-prone routine needs ingredients that directly target breakouts and blemishes.
Can I use this serum with retinol, and in what order?
You can use this treatment with retinol by applying the treatment after your cleanser and before your moisturizer in your evening routine. This product is unlikely to cause irritation on your oily skin, though an oily acne-prone skin type needs targeted ingredients like salicylic acid or benzoyl peroxide to directly manage breakouts.
How often should I use this serum?
This treatment serum works well in your evening routine, where you can safely apply it on clean skin once a day or a few times a week. It is safe for oily skin and unlikely to cause irritation, though managing breakouts effectively typically requires targeted ingredients like salicylic acid or benzoyl peroxide.
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is unlikely to clog pores or cause irritation for your oily skin, as it contains gentle ingredients without harsh components. However, because it offers limited direct care for acne and breakouts, an oily acne-prone skin type needs added ingredients like salicylic acid or niacinamide to truly clear and balance blemishes.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Fibrin-bound keratinocyte growth factor released via cell-mediated degradation significantly enhanced wound closure in a hybrid model of full-thickness wound healing in athymic mice compared to topical KGF.
The American Journal of Pathology, 2005A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone.
The New England Journal of Medicine, 1989Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba.
Lasers in Surgery and Medicine, 2020Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars.
The Journal of Clinical and Aesthetic Dermatology, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide.
Journal of Cosmetic Dermatology, 2007N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers.
Advanced Pharmaceutical Bulletin, 2016Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants.
Journal of Cosmetic and Laser Therapy, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012
Why other serums fit oily acne-prone skin better
A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Glycerin, Water, Sodium Citrate, Acetyl Glucosamine Nag, Isopentyldiol, Phenoxyethanol, Sodium Chloride, Sodium Hyaluronate, Citric Acid, Hordeum Vulgare Seed Extract, Rh-Oligopeptide-1 Barley Sh-Oligopeptide-1, Kgf Barley Sh-Polypeptide-3
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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