Bioderma Sensibio Lait Cleansing Milk for mature skin
Glycyrrhetinic Acid
Squalane
Mannitol
Rhamnose
Laminaria Ochroleuca Extract
High
- HighNormal Skin Fit
- HighEffectiveness
- HighSafety
A great choice for mature skin; a few pre-cleansers fit it even better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your normal skin, this product effectively removes makeup with paraffinum liquidum mineral oil and squalane, which dissolve impurities without causing dryness. Glycerin and squalane further support your normal skin by providing essential hydration and emollient benefits.
- While it offers general skincare benefits like cleansing and soothing, its primary function is not targeted towards addressing wrinkles and fine lines.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of harsh ingredients and the inclusion of soothing Glycyrrhetinic Acid.
How to apply
- Use this makeup remover as part of your PM routine every evening. Start 3x/week and move to daily use as your skin feels comfortable.
- Apply this makeup remover before your regular cleanser and toner. It acts as the very first step to melt away makeup.
- Gently massage a small amount of the makeup remover over dry skin to dissolve makeup, then rinse with warm water. Avoid any harsh rubbing around your eyes.
- Apply this makeup remover directly onto dry skin to effectively break down stubborn makeup and impurities. There is no need to dampen your face beforehand.
- Do a patch test before your first use to ensure your skin reacts well. Avoid direct contact with your eyes while cleansing.
People Say
★4.2Overall rating based on 100+ reviewsUsers with oily or combination skin often find it leaves a greasy film, and many users report it struggles to remove heavy waterproof makeup without a second cleanse.
Highlights
Extremely gentle Often Mentioned
- “soothes irritated skin”
- “never stings”
- “calms redness”
- “doesn't strip barrier”
Hydrating texture Often Mentioned
- “creamy consistency”
- “leaves skin soft”
- “moisturizing feel”
- “good for dry patches”
Leaves residue Often Mentioned
- “greasy film”
- “sticky after-feel”
- “waxy coating”
- “felt heavy”
Weak on makeup Often Mentioned
- “struggles with mascara”
- “doesn't remove waterproof”
- “requires double cleanse”
- “left foundation behind”
Versatile application Sometimes Noted
- “can tissue off”
- “rinse optional”
- “good morning cleanse”
- “use with cotton pad”
Contains mineral oil Rarely Noted
- “caused breakouts”
- “clogged pores”
- “dislike paraffin”
- “not for acne-prone”
Eye irritation Rarely Noted
- “cloudy vision”
- “stings eyes”
- “film over eyes”
- “migrates into eyes”
Sources: lovi.care, dermstore.com, skinsort.com, makeupalley.com, beautyandlifestylehunter.blogspot.com, beautifulbuns.wordpress.com, and more
Questions and answers
What makes Bioderma Sensibio Lait a great fit for mature skin?
Bioderma Sensibio Lait Cleansing Milk is a great fit for mature skin because it effectively removes makeup using mineral oil and squalane without causing dryness, while glycerin and squalane keep skin soft by providing essential hydration. It also helps calm the skin with soothing glycyrrhetinic acid, making it very gentle and unlikely to cause irritation.
Which ingredients make this cleanser a good fit for mature skin?
This cleanser is a great fit for mature skin because it contains paraffinum liquidum mineral oil and squalane to dissolve impurities without causing dryness, alongside glycerin and squalane to provide essential hydration. It also features soothing glycyrrhetinic acid, making it very gentle and unlikely to irritate your skin.
What does Glycyrrhetinic Acid do for mature skin?
Glycyrrhetinic acid helps calm redness and soothe irritation in mature skin, making it feel more comfortable. It is often paired with gentle hydrators and soothing ingredients to support a healthy skin barrier.
What does Squalane do for mature skin?
Squalane helps keep mature skin feeling soft and smooth by boosting moisture and protecting the skin barrier. It also provides antioxidant support that helps improve the look of fine lines and wrinkles over time.
Journal of Nanobiotechnology, 2025Journal of Nanoscience and Nanotechnology, 2010
Where does this cleanser go in a skincare routine for mature skin?
This makeup remover goes in the evening routine before your cleanser, and as part of your weekly routine. Using a gentle cleanser and moisturizer helps improve skin feel and visual dryness.
Can I use it with retinol, and in what order?
Yes, you can use this makeup remover in your evening routine before applying retinol treatments. Its gentle, soothing formula is unlikely to cause irritation when paired with active ingredients.
How often should I use this cleanser?
You can use this makeup remover daily as the first step of your evening routine. It effectively dissolves impurities without causing dryness and has an excellent safety profile with no risks of irritation for your skin.
Can this cleanser clog pores, cause breakouts or purging for mature skin?
This cleanser is unlikely to cause breakouts or clog pores for mature skin because it has an excellent safety profile without harsh ingredients. It uses soothing glycyrrhetinic acid and hydrating glycerin to gently cleanse and comfort your skin without irritation.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A dermo-cosmetic formula containing 2% enoxolone significantly reduced erythema at 24 hours and pain at 30 minutes following non-ablative fractional laser treatment in 10 healthy subjects compared to a moisturizer control.
Journal of Cosmetic Dermatology, 2024Topical application of a cream containing 2.5% glycyrrhetinic acid significantly reduced thigh fat thickness and circumference compared to placebo in healthy women.
Steroids, 2005Topical application of B-Resorcinol and Glycyrrhetinic acid effectively lightens hand solar lentigines after 4 weeks of treatment both with and without prior fractional laser photothermolysis, showing no statistical difference between the two approaches.
Journal of Cosmetic Dermatology, 2016Glycyrrhetinic acid inhibited skin 11 beta-hydroxysteroid dehydrogenase and potentiated the vasoconstrictor action of hydrocortisone.
Lancet, 1990Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Combining ectoine and mannitol with UV filters significantly improved protection of squalene oxidation, catalase activity, and trans-UCA compared to UV filters alone in 10 subjects on irradiated areas.
Journal of Cosmetic Dermatology, 2024Topical mannitol cream reduced self-reported pain scores compared to a control cream in 25 adults with capsaicin-induced lip pain.
PM & R, 2015A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris.
Clinical, Cosmetic and Investigational Dermatology, 2015Rhamnose exerts beneficial anti-ageing effects on the papillary dermis and dermal-epidermal junction, including increased collagen IV and procollagen I production in vivo.
International Journal of Cosmetic Science, 2019Hesperidin, hesperetin, rutinose, and rhamnose reduced MMP-1 and MMP-2 levels, while rutinose and rhamnose also inhibited elastase, hyaluronidase, and collagenase and increased collagen I production in young and physiologically aged normal human dermal fibroblasts.
Molecules, 2023
Ingredients
Water, Glycerin, Cetearyl Isononanoate, Paraffinum Liquidum Mineral Oil, Mannitol, Xylitol, Rhamnose, Fructooligosaccharides, Laminaria Ochroleuca Extract, Glycyrrhetinic Acid, Squalane, Pentylene Glycol, Caprylic Capric Triglyceride, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Tocopherol, Ethylhexylglycerin, Disodium Edta, Sodium Hydroxide
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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