Alastin Skincare A-Luminate Brightening Serum for sensitive skin

How to apply

Questions and answers

What the research says

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• An optimized quercetin and hesperidin 8:1 complex restored antioxidant enzyme activities, suppressed inflammatory cytokine production, and reduced allergic response marker levels more effectively than alpha-glucosylrutin in in vitro and ex vivo models of sun-induced skin damage.

  Current Issues in Molecular Biology, 2025

• Hesperidin, hesperetin, rutinose, and rhamnose reduced MMP-1 and MMP-2 levels, while rutinose and rhamnose also inhibited elastase, hyaluronidase, and collagenase and increased collagen I production in young and physiologically aged normal human dermal fibroblasts.

  Molecules, 2023

• Hesperidin protects human HaCaT keratinocytes against PM2.5-induced damage by reducing intracellular reactive oxygen species generation, autophagy, and apoptosis, and restoring cell viability via Akt activation compared to PM2.5 exposure alone.

  Antioxidants, 2022

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers.

  Journal of Cosmetic Dermatology, 2021

• Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models.

  Archives of Dermatological Research, 2023

• Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts.

  In Vivo, 2022

Ingredients

Water, Squalane, Glycerin, Niacinamide, Sodium Acrylates Copolymer, Thermus Thermophillus Ferment, Tranexamic Acid, Glucosyl Hesperidin, Silybum Marianum Milk Extract, Lactoferrin, Plankton Extract, Tremella Fuciformis Sporocarp Extract Silver Ear Mushroom Extract, Pancratium Maritimum Extract Sea Daffodil Extract, Dunaliella Salina Extract, Pentasodium Tetracarboxymethyl Acetylhydroxyprolyl Dipeptide-12, Hexapeptide-11, Hexapeptide-12, Pentasodium Tetracarboxymethyl Dipeptide-51, Phosphatidylserine, Diglucosyl Gallic Acid, Fructose, Betaine, Ascorbyl Palmitate, Propanediol, Lecithin, Caprylyl Methicone, Dimethicone, Mannitol, Phosphatidylcholine, 1,2-Hexanediol, Cetyl Alcohol, Xanthan Gum, Tocopherol, Citric Acid, Helianthus Annuus Seed Oil Sunflower Seed Oil, Decyl Glucoside, Caprylyl Glycol, Ethylhexylglycerin, Caprylhydroxamic Acid, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Sodium Chloride, Silica, Tin Oxide Ci 77861, Titanium Dioxide Ci 77891

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.