Vitamin C and copper peptide
Keep them apart
Apply vitamin C in the morning and copper peptides at night, because combining them makes both ingredients less effective. Copper reacts with vitamin C and neutralizes their anti-aging benefits. You can use both by separating them into different times of day.
Microneedle-Mediated Delivery of Copper Peptide Through Skin
Vitamin C products
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Olay
Super Serum
拢24.05
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Charlotte Tilbury
Charlotte's Magic Cream
拢33.07
-
RoC
Retinol Correxion Deep Wrinkle Night Cream
拢19.34
-
Paula's Choice
1% Retinol Treatment
拢39.97
- Summer Fridays Jet Lag Mask
-
Mad Hippie
Vitamin C Serum
拢26.99
- Eve Lom Renewal Treatment Oil
- ZO Skin Health Exfoliating Polish
-
CeraVe
Skin Renewing Vitamin C Serum
拢19.98
-
Eucerin
Anti-Pigment Dual Serum
拢29.99
-
RoC
Retinol Correxion Deep Wrinkle Serum
拢18.49
-
iS Clinical
Cleansing Complex
拢44.00
Copper peptide products
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The Ordinary
Multi-Peptide + Copper Peptides 1% Serum
拢28.90
-
Biossance
Squalane + Copper Peptide Rapid Plumping Serum
拢41.20
-
Good Molecules
Super Peptide Serum
拢17.00
-
Allies of Skin
Copper Tripeptide & Ectoin Advanced Repair Serum
拢140.79
-
COSRX
Advanced Snail Peptide Eye Cream
拢16.83
-
Hero Cosmetics
Rescue Balm
拢6.49
- Mederma PM Intensive Overnight Scar Cream
- ma:nyo Bifida Biome Complex Ampoule
- MISSHA Time Revolution Night Repair Ampoule
- Peach & Lily Copper Peptide Pro Firming Serum
- Theramid Copper Peptide
-
SKIN1004
Zombie Pack
拢21.99
Questions and answers
Can you use vitamin C and copper peptide together?
No, you should keep vitamin C and copper peptide apart in separate routines because copper acts as an oxidation catalyst that reduces peptide efficacy. Perricone MD Cold Plasma Plus+ is a product on this page that contains both ingredients.
Which goes first, vitamin C or copper peptide?
Keep vitamin C and copper peptide apart by using them in separate routines because copper acts as an oxidation catalyst that reduces peptide efficacy. Perricone MD Cold Plasma Plus+ is an exception that combines both in one product.
Are vitamin C and copper peptide good for sensitive skin?
Vitamin C and copper peptide should be kept apart in separate routines because combining them may reduce their efficacy. Perricone MD Cold Plasma Plus+ is an example of a product containing both.
Research on vitamin C and copper peptide
Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin
Efficacy of ethyl ascorbyl ether-containing cosmetic cream on blue light-induced skin changes
Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations
Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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