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Retinol and citric acid

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Retinol and citric acid: keep them apart

Keep them apart

Use them on alternate nights, applying citric acid first and retinol next, to prevent skin irritation and over-exfoliation. Both ingredients increase skin cell turnover and can cause redness, peeling, or a damaged barrier when used together. The shopper can switch to a gentler strength or add more time between applications.

Photocarcinogenesis study of glycolic acid and salicylic acid (CAS Nos. 79-14-1 and 69-72-7) in SKH-1 mice (simulated solar light and topical application study)Novel retinoid ester in combination with salicylic acid for the treatment of acne

Retinol products

Citric acid products

Questions and answers

Can you use retinol and citric acid together?

Keep retinol and citric acid apart in your routine to avoid over-exfoliation and irritation. Instead, alternate evenings or use a moisturizer between applications.

Which goes first, retinol or citric acid?

Keep retinol and citric acid apart by alternating them on different evenings to help prevent over-exfoliation and skin irritation.

Are retinol and citric acid good for sensitive skin?

Keep retinol and citric acid apart because layering them may cause over-exfoliation and irritation. Alternate evenings or buffer with moisturizer between uses to protect sensitive skin.

Research on retinol and citric acid

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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