Vichy Liftactiv Specialist B3 Serum for mature skin
Niacinamide
Glycolic Acid
Tranexamic Acid
Ascorbyl Glucoside
Hydrolyzed Rice Protein
Average
- HighNormal Skin Fit
- AverageEffectiveness
- Low RiskSafety
Works for mature skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate exfoliation and evening of skin tone for your normal skin, as niacinamide and glycolic acid promote skin renewal and reduce hyperpigmentation.
- While beneficial for general skincare, the hydration and mild resurfacing provided are not specifically targeted for your wrinkles and fine lines.
- The formula is generally safe for your normal skin, with a low risk of irritation from glycolic acid and ascorbyl glucoside.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.5Overall rating based on 1.0k+ reviewsBased on a very large amount of data, this serum is highly praised by users dealing with hyperpigmentation, dullness, and uneven skin tone for its ability to visibly fade dark spots and brighten the complexion. Its lightweight, fast-absorbing formula is frequently noted as gentle on sensitive skin. Some users indicate that consistent, long-term use is necessary to see significant results on stubborn dark spots and deep wrinkles.
Highlights
Evens skin tone Often Mentioned
- “it has seemed to have evened my skin tone as I used to have alot of dark patches”
- “My skin looks brighter and more plump”
- “I can see my skin is brighter and glowing after 3 weeks.”
- “Now I have radiant, even and smooth skin.”
Fades dark spots Often Mentioned
- “I have definitely noticed a difference in my dark spots they seem to be slowly fading”
- “helps me correct some dark pigmentation spots I had on my left cheek.”
- “Helps with smoothing fine lines & fading dark spots!”
- “diminishing the appearance of dark spots and evening out skin tone.”
Lightweight and fast-absorbing Often Mentioned
- “The formula is so light and doesn't leave skin feeling oily.”
- “It absorbs quickly into my skin and is so smooth”
- “This lightweight, non-greasy serum absorbs quickly into the skin without leaving a sticky residue.”
- “The serum is light and Its absorbs quite quickly and it's not sticky”
Gentle on sensitive skin Sometimes Noted
- “This is a great serum for sensitive skin.”
- “I like it doesn't irritate my skin.”
- “didn't cause me any negative reaction and my skin felt smoother”
- “gentle on sensitive skin.”
Takes time for results Sometimes Noted
- “haven't seen a change in dark spots but I need to give it more time”
- “It's still too early to tell any visible difference”
- “hopeful that with continued use I will see the changes”
- “Repeated use and time will tell.”
Applicator design issues Rarely Noted
- “The only issue I have with it is the applicator, I wish it had a drop applicator instead so I don't waste so much product”
- “The applicator... is a bit unique. With the long pointed tip offering precision, I felt like a scientist”
- “I wish it had a drop applicator instead so I don't waste so much product”
Ineffective on deep wrinkles Rarely Noted
- “so far have not seen any improvement in my deep wrinkles.”
- “I'm hoping in time I will see some results.”
- “haven't seen any improvement in my deep wrinkles.”
Sources: lovi.care, dermstore.com, lookfantastic.com, walmart.ca, my-origines.com, lovelyskin.com, and more
Questions and answers
How well does Vichy Liftactiv B3 Serum work for mature skin?
Vichy Liftactiv Specialist B3 Serum is an average fit for mature skin because, while Niacinamide and Glycolic Acid help even out skin tone and renew the surface, the hydration and mild resurfacing are not specifically targeted for wrinkles and fine lines. A treatment for mature skin needs exceptionally safe and effective anti-aging ingredients like peptides, high concentrations of antioxidants, and deep hydrators to improve firmness and smooth lines without irritation.
The British Journal of Dermatology, 2002Journal of Cosmetic Dermatology, 2021
Which ingredients make this serum a good fit for mature skin?
Niacinamide and glycolic acid make this serum a good fit by helping to even out skin tone and gently renewing your skin. To properly care for mature skin, a product of this type needs powerful antioxidants, hydrating components, and ingredients that specifically target wrinkles and improve skin elasticity.
The British Journal of Dermatology, 2002Journal of Cosmetic Dermatology, 2021
What does Niacinamide do for mature skin?
Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
What does Glycolic Acid do for mature skin?
Glycolic acid helps smooth mature skin by encouraging fresh skin renewal and supporting firmness. It may also help improve signs of photoaging and increase moisture levels over time.
Where does this serum go in a skincare routine for mature skin?
This serum goes in the evening routine after cleansing and before moisturizing, following a schedule of once a week at first and increasing only if your skin handles it well. Put treatments in the evening for simplicity and extra safety around sun exposure. Mature skin of this type needs richer anti-aging ingredients like potent retinoids and firming peptides that specifically target wrinkles and fine lines.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the treatment after your cleanser and before your moisturizer in the evening, but you should introduce them slowly to keep your skin calm. Because this product contains exfoliating acids, using both at the same time may increase the likelihood of dryness or irritation on mature skin.
How often should I use this serum?
Use this treatment in your evening routine once a week to start, and if your skin tolerates it well and you see good results, you may carefully use it more often. A product for mature skin needs ingredients like retinoids and concentrated hydrators to target wrinkles and fine lines.
Can this serum clog pores, cause breakouts or purging for mature skin?
This serum is unlikely to clog pores or cause breakouts for mature skin, as its formula has a low risk of irritation and is generally safe for daily use. However, because it works to smooth and renew the skin, a product of this type needs richer hydrating ingredients and targeted wrinkle smoothers to truly care for mature skin.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.
The British Journal of Dermatology, 2002Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women.
Scientific Reports, 2024Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline.
Journal of Cosmetic and Laser Therapy, 2006Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks.
International Journal of Dermatology, 2000Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone.
Dermatologic Surgery, 2017Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression.
Food & Function, 2020
Why other serums fit mature skin better
Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline.
In Vivo, 2023Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020
Ingredients
Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Hydroxyethyl Urea, Propylene Glycol, Glycolic Acid, Tranexamic Acid, Allantoin, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin, Ascorbyl Glucoside, Caprylyl Glycol, Hydrolyzed Rice Protein, Vitreoscilla Ferment, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Pentylene Glycol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Elina Nazarenko, MD
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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